Basic Information
ID: ALA3129815
Type: Binding
Description: Inhibition of recombinant topoisomerase-1 (unknown origin) assessed as inhibition of 3'-[32P]-labeled DNA cleavage at 0.1 to 100 uM after 20 mins by PAGE analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3129815
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.39 | 1.31 | 1.31 |
| 425.39 | 1.31 | 1.31 |
| 425.39 | 1.31 | 1.31 |
| 485.45 | 0.03 | 0.03 |
| 485.45 | 0.03 | 0.03 |
| 485.45 | 0.03 | 0.03 |
| 485.45 | 0.03 | 0.03 |
| 515.47 | -0.61 | -0.61 |
| 515.47 | -0.61 | -0.61 |
| 515.47 | -0.61 | -0.61 |
| 527.48 | -0.20 | -0.20 |
| 366.33 | 1.47 | 1.47 |
| 366.33 | 1.47 | 1.47 |
| 426.38 | 0.20 | 0.20 |
| 426.38 | 0.20 | 0.20 |
| 426.38 | 0.20 | 0.20 |
| 426.38 | 0.20 | 0.20 |
| 456.41 | -0.44 | -0.44 |
| 456.41 | -0.44 | -0.44 |
| 468.42 | -0.04 | -0.04 |