Basic Information
ID: ALA3130038
Type: Binding
Description: Binding affinity to eIF4A1/2 in rabbit reticulocyte lysate assessed as inhibition of cap-dependent translation after 1.5 hrs by dual luciferase reporter gene assay
Organism: Oryctolagus cuniculus
Activity Charts
Bioactivity
Activity Types for Assay ALA3130038
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.67 | 5.52 | 5.52 |
| 485.65 | 4.87 | 4.87 |
| 482.44 | 5.45 | 5.45 |
| 526.74 | 6.16 | 6.16 |
| 526.74 | 6.16 | 6.16 |
| 568.78 | 5.93 | 5.93 |
| 552.78 | 6.69 | 6.69 |
| 485.65 | 5.20 | 5.20 |
| 480.42 | 4.89 | 4.89 |
| 566.76 | 5.38 | 5.38 |
| 550.77 | 6.14 | 6.14 |
| 497.66 | 5.30 | 5.30 |
| 483.63 | 4.65 | 4.65 |