Basic Information
ID: ALA3130225
Type: Binding
Description: Inhibition of human DHFR using dihydrofolate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric analysis in presence of NADPH
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3130225
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 454.45 | 0.27 | 0.27 |
| 354.41 | 2.43 | 2.43 |
| 436.86 | 4.06 | 4.06 |
| 413.44 | 3.21 | 3.21 |
| 383.46 | 3.76 | 3.76 |
| 381.44 | 3.81 | 3.81 |
| 381.44 | 3.81 | 3.81 |
| 381.44 | 3.81 | 3.81 |
| 410.48 | 4.43 | 4.43 |
| 344.42 | 3.63 | 3.63 |
| 389.46 | 2.59 | 2.59 |
| 374.45 | 3.25 | 3.25 |
| 374.45 | 3.60 | 3.60 |
| 401.50 | 4.18 | 4.18 |
| 421.92 | 4.53 | 4.53 |
| 420.93 | 5.13 | 5.13 |
| 419.47 | 3.27 | 3.27 |
| 433.50 | 3.58 | 3.58 |
| 453.92 | 3.93 | 3.93 |
| 452.93 | 4.53 | 4.53 |
| 304.36 | 2.75 | 2.75 |
| 387.47 | 3.87 | 3.87 |
| 387.47 | 3.87 | 3.87 |
| 370.42 | 4.01 | 4.01 |
| 370.42 | 4.01 | 4.01 |
| 386.48 | 4.48 | 4.48 |
| 386.48 | 4.48 | 4.48 |
| 384.45 | 3.15 | 3.15 |