Basic Information
ID: ALA3131107
Type: Binding
Description: Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SUM159
Activity Charts
Bioactivity
Activity Types for Assay ALA3131107
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.61 | 6.33 | 6.33 |