ID: ALA3131107
Type: Binding
Description: Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SUM159
Target: IL6Ralpha/GP130(ALA3137266)
Document: ALA3124858
Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis: 1
Bioactivity
Activity Types for Assay ALA3131107
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
470.61 | 6.33 | 6.33 |