Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphor...

Basic Information

ID: ALA3131107

Type: Binding

Description: Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: SUM159

Target:  IL6Ralpha/GP130(ALA3137266)

Document:  ALA3124858

Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 10 to 30 uM after 24 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
470.616.336.33