Basic Information
ID: ALA3131111
Type: Binding
Description: Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 15 to 50 uM after 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SUM159
Target: IL6Ralpha/GP130(ALA3137266)
Document: ALA3124858
Inhibition of IL-6Ralpha/GP130 interaction in ER-negative human SUM159 cells overexpressing IL-6 assessed as inhibition of constitutive STAT3 phosphorylation at Y705 at 15 to 50 uM after 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3131111
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.59 | 6.08 | 6.08 |