Assay Report Card

Basic Information

ID: ALA3131300

Type: Functional

Description: Antitumor activity against human A375 cells expressing BRAF V600E mutant xenografted in F344 nude rat assessed as reduction in tumor size at 9.7 mg/kg, po bid for 14 days relative to control

Organism: Homo sapiens

Cell type: A-375

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
554.536.656.65