Basic Information
ID: ALA3131527
Type: Binding
Description: Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins followed by glucose addition measured after 40 mins by fluorescence assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Hepatocyte
Target: Glucokinase regulatory protein(ALA3124733)
Document: ALA3124752
Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins followed by glucose addition measured after 40 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3131527
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 533.64 | 3.12 | 3.12 |
| 474.45 | 3.57 | 3.57 |
| 572.59 | 4.76 | 4.76 |
| 573.58 | 3.27 | 3.27 |
| 587.61 | 3.66 | 3.66 |
| 518.62 | 4.21 | 4.21 |
| 518.62 | 4.21 | 4.21 |
| 533.64 | 3.12 | 3.12 |