Assay Report Card

Basic Information

ID: ALA3131804

Type: Binding

Description: Activity at CFTR F508del mutant (unknown origin) expressed in Fischer rat thyroid epithelial cells co-expressing YFP-H148Q/I152L assessed as forskolin/PG-01-induced increase in conductance reversible effect at 10 to 20 uM after 16 to 20 mins by conductance corrector assay in presence of CFInh-172

Organism: Homo sapiens

Cell type: Epithelial cell

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
591.690.250.25
559.62-0.40-0.40