ID: ALA3131804
Type: Binding
Description: Activity at CFTR F508del mutant (unknown origin) expressed in Fischer rat thyroid epithelial cells co-expressing YFP-H148Q/I152L assessed as forskolin/PG-01-induced increase in conductance reversible effect at 10 to 20 uM after 16 to 20 mins by conductance corrector assay in presence of CFInh-172
Organism: Homo sapiens
Cell type: Epithelial cell
Bioactivity
Activity Types for Assay ALA3131804
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
591.69 | 0.25 | 0.25 |
559.62 | -0.40 | -0.40 |