Basic Information
ID: ALA3132417
Type: Functional
Description: Anticonvulsant activity in Sprague-Dawley rat hippocampus assessed as inhibition of population spike amplitude at >= 100 uM preincubated for 6 mins followed by compound washout measured after 10 mins by blind patch-clamp technique
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Hippocampus
Activity Charts
Bioactivity
Activity Types for Assay ALA3132417
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.22 | 4.08 | 4.08 |
| 431.12 | 4.30 | 4.30 |
| 373.09 | 4.90 | 4.90 |
| 479.17 | 5.05 | 5.05 |
| 345.03 | 4.26 | 4.26 |
| 417.10 | 3.91 | 3.91 |
| 417.10 | 4.05 | 4.05 |
| 359.06 | 4.51 | 4.51 |
| 573.17 | 4.74 | 4.74 |
| 587.19 | 5.13 | 5.13 |