Basic Information
ID: ALA3132469
Type: Binding
Description: Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay in presence of 15% human serum
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3132469
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.42 | 5.69 | 5.69 |
| 526.48 | 5.35 | 5.35 |
| 540.51 | 5.74 | 5.74 |
| 540.51 | 5.74 | 5.74 |
| 552.52 | 5.89 | 5.89 |
| 554.54 | 6.13 | 6.13 |
| 568.56 | 6.52 | 6.52 |
| 566.55 | 6.14 | 6.14 |
| 566.55 | 6.28 | 6.28 |
| 580.57 | 6.67 | 6.67 |
| 568.52 | 5.12 | 5.12 |
| 588.55 | 6.78 | 6.78 |
| 492.44 | 6.08 | 6.08 |
| 506.47 | 6.47 | 6.47 |
| 520.50 | 6.86 | 6.86 |
| 492.44 | 6.08 | 6.08 |
| 492.44 | 6.08 | 6.08 |
| 473.40 | 6.22 | 6.22 |
| 515.48 | 7.25 | 7.25 |