Basic Information
ID: ALA3132546
Type: ADME
Description: Prodrug activation in dog serum assessed as formation of (S)-2-((((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)oxidophosphorylamino)propanoate at 5 mg measured after 6.5 mins by [31P]-NMR spectroscopic analysis
Organism: Canis lupus familiaris
Tissue: Serum
Activity Charts
Bioactivity
Activity Types for Assay ALA3132546
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 580.48 | 2.64 | 2.64 |