Basic Information
ID: ALA3134967
Type: Binding
Description: Inhibition of DOT1L (unknown origin) using [methyl-3H]SAM and biotinylated nucleosome PRC2 and H3K27Me3 activator peptide up to 80 uM by [3H]methyl group incorporation assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3134967
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.77 | 3.02 | 3.02 |
| 363.80 | 2.78 | 2.78 |
| 317.82 | 3.88 | 3.88 |
| 305.76 | 3.03 | 3.03 |
| 289.76 | 3.32 | 3.32 |
| 361.83 | 3.34 | 3.34 |
| 430.93 | 3.11 | 3.11 |
| 361.83 | 3.34 | 3.34 |
| 347.84 | 3.25 | 3.25 |
| 347.80 | 2.95 | 2.95 |
| 407.81 | 2.24 | 2.24 |
| 361.83 | 3.94 | 3.94 |
| 347.84 | 3.70 | 3.70 |
| 331.80 | 3.33 | 3.33 |
| 315.34 | 2.82 | 2.82 |
| 376.25 | 3.44 | 3.44 |
| 327.38 | 2.68 | 2.68 |
| 342.35 | 2.58 | 2.58 |
| 298.34 | 2.07 | 2.07 |
| 399.80 | 4.35 | 4.35 |
| 349.79 | 3.47 | 3.47 |
| 347.80 | 3.30 | 3.30 |
| 333.77 | 3.62 | 3.62 |
| 375.85 | 3.90 | 3.90 |
| 375.85 | 3.58 | 3.58 |
| 359.81 | 3.42 | 3.42 |
| 375.85 | 3.68 | 3.68 |
| 360.84 | 2.74 | 2.74 |
| 374.87 | 3.00 | 3.00 |
| 388.90 | 3.34 | 3.34 |