Assay Report Card

Basic Information

ID: ALA3136203

Type: Binding

Description: Noncompetitive mixed type inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase assessed as reduction in enzyme Vmax using H2folate substrate by steady state kinetic assay

Organism: Cryptosporidium hominis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
622.726.686.68
634.777.697.69