ID: ALA3136681
Type: Binding
Description: Inhibition of 53BP1 (1485 to 1611) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3136681
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
338.25 | 2.54 | 2.54 |
529.73 | 4.83 | 4.83 |
466.67 | 3.87 | 3.87 |
355.57 | 4.17 | 4.17 |
341.54 | 3.78 | 3.78 |
343.52 | 2.63 | 2.63 |
385.55 | 2.74 | 2.74 |
355.53 | 2.63 | 2.63 |
361.96 | 4.04 | 4.04 |
327.52 | 3.39 | 3.39 |
341.54 | 3.78 | 3.78 |
313.49 | 3.35 | 3.35 |
341.54 | 3.78 | 3.78 |
327.52 | 3.39 | 3.39 |
313.49 | 3.35 | 3.35 |
258.41 | 2.92 | 2.92 |
355.53 | 3.31 | 3.31 |
327.47 | 2.99 | 2.99 |
382.60 | 3.82 | 3.82 |
230.35 | 2.75 | 2.75 |
352.53 | 3.14 | 3.14 |
341.50 | 2.57 | 2.57 |
313.49 | 3.00 | 3.00 |
349.47 | 3.24 | 3.24 |
373.54 | 1.58 | 1.58 |