Basic Information
ID: ALA3137097
Type: Binding
Description: Inhibition of PHD3 in human NCI-H446 cells grown under normoxia assessed as HIF1alpha accumulation measured as increase in GLUT1 protein expression at 25 uM after 12 hrs by Western blot analysis relative to untreated control
Organism: Homo sapiens
Cell type: NCI-H446
Activity Charts
Bioactivity
Activity Types for Assay ALA3137097
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 140.14 | 0.36 | 0.36 |
| 141.13 | -0.25 | -0.25 |
| 190.20 | 1.51 | 1.51 |
| 191.19 | 0.91 | 0.91 |
| 213.24 | 1.40 | 1.40 |
| 263.30 | 2.55 | 2.55 |