Basic Information
ID: ALA3137098
Type: Binding
Description: Inhibition of PHD3 in human NCI-H446 cells grown under normoxia assessed as HIF1alpha accumulation measured as increase in VEGF gene expression at 25 uM after 12 hrs by RT-PCR analysis relative to untreated control
Organism: Homo sapiens
Cell type: NCI-H446
Activity Charts
Bioactivity
Activity Types for Assay ALA3137098
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 141.13 | -0.25 | -0.25 |
| 190.20 | 1.51 | 1.51 |
| 191.19 | 0.91 | 0.91 |
| 213.24 | 1.40 | 1.40 |
| 263.30 | 2.55 | 2.55 |