Basic Information
ID: ALA3214804
Type: Functional
Description: PubChem BioAssay. Late stage counterscreen for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS): Luminescence-based cell-based high throughput dose response assay to identify compounds that are cytotoxic to Jurkat human T lymphocyte cells. (Class of assay: confirmatory)
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA3214804
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.21 | 3.89 | 3.89 |
| 315.76 | 2.82 | 2.82 |
| 513.39 | 2.78 | 2.78 |
| 358.76 | 3.29 | 3.29 |
| 469.54 | 4.30 | 4.30 |
| 449.55 | 4.18 | 4.18 |
| 508.44 | 5.02 | 5.02 |
| 308.17 | 4.19 | 4.19 |
| 433.51 | 3.54 | 3.54 |
| 386.76 | 1.90 | 1.90 |
| 500.39 | 4.14 | 4.14 |
| 465.51 | 3.11 | 3.11 |
| 406.24 | 2.99 | 2.99 |
| 350.80 | 2.91 | 2.91 |
| 548.44 | 5.06 | 5.06 |
| 469.54 | 4.30 | 4.30 |
| 433.51 | 3.54 | 3.54 |
| 344.76 | 3.10 | 3.10 |
| 548.44 | 5.06 | 5.06 |
| 434.45 | 2.14 | 2.14 |
| 476.53 | 3.58 | 3.58 |
| 361.37 | 1.87 | 1.87 |
| 310.28 | 3.17 | 3.17 |
| 397.46 | 4.14 | 4.14 |
| 346.37 | 2.53 | 2.53 |
| 360.24 | 3.84 | 3.84 |
| 296.29 | 2.58 | 2.58 |
| 379.45 | 3.51 | 3.51 |
| 451.31 | 5.68 | 5.68 |
| 347.76 | 3.78 | 3.78 |
| 397.44 | 3.01 | 3.01 |
| 377.26 | 5.21 | 5.21 |
| 318.83 | 4.53 | 4.53 |
| 409.43 | 2.97 | 2.97 |
| 371.85 | 3.78 | 3.78 |
| 477.59 | 4.60 | 4.60 |
| 414.81 | 2.54 | 2.54 |
| 419.28 | 4.65 | 4.65 |
| 349.27 | 4.39 | 4.39 |
| 390.40 | 2.39 | 2.39 |
| 379.31 | 4.78 | 4.78 |
| 542.27 | 5.98 | 5.98 |
| 459.42 | 3.34 | 3.34 |
| 458.39 | 4.41 | 4.41 |
| 508.00 | 4.92 | 4.92 |
| 360.45 | 3.71 | 3.71 |
| 514.42 | 4.39 | 4.39 |
| 447.54 | 3.22 | 3.22 |
| 342.48 | 4.95 | 4.95 |
| 449.55 | 4.18 | 4.18 |
| 477.59 | 4.60 | 4.60 |
| 465.51 | 3.11 | 3.11 |
| 514.42 | 4.39 | 4.39 |
| 500.39 | 4.14 | 4.14 |