Basic Information
ID: ALA3214810
Type: Functional
Description: PubChem BioAssay. Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Fischer Rat Thyroid (FRT) Cells. Measured in Cell-Based System Using Plate Reader - 7017-02_Other_Dose_CherryPick_Activity. (absACnn = the concentration at which the curve crosses threshold nn uM) (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214810
AbsAC35_uM
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 238.29 | 3.12 | 3.12 |
| 427.45 | 2.68 | 2.68 |
| 280.36 | 1.96 | 1.96 |
| 394.32 | 4.13 | 4.13 |
| 279.39 | 3.75 | 3.75 |
| 262.30 | 1.25 | 1.25 |
| 729.78 | 1.42 | 1.42 |
| 259.74 | 1.98 | 1.98 |
| 293.33 | 3.30 | 3.30 |
| 412.47 | 3.34 | 3.34 |
| 402.55 | 5.31 | 5.31 |
| 563.99 | 1.03 | 1.03 |
| 263.32 | 3.76 | 3.76 |
| 334.33 | -1.65 | -1.65 |
| 290.26 | 1.92 | 1.92 |
| 438.51 | 3.49 | 3.49 |
| 313.20 | 5.05 | 5.05 |
| 318.42 | 4.08 | 4.08 |
| 220.28 | 2.93 | 2.93 |
| 364.53 | 5.23 | 5.23 |
| 388.52 | 5.57 | 5.57 |
| 248.71 | 2.97 | 2.97 |
| 384.48 | 3.45 | 3.45 |
| 563.99 | 1.03 | 1.03 |
| 316.38 | 2.98 | 2.98 |
| 240.26 | 1.56 | 1.56 |
| 324.34 | 2.66 | 2.66 |
| 316.45 | 3.33 | 3.33 |
| 360.50 | 4.29 | 4.29 |
| 251.17 | 1.24 | 1.24 |
| 388.52 | 5.57 | 5.57 |
| 371.53 | 4.75 | 4.75 |
| 267.38 | 3.69 | 3.69 |
| 328.33 | 0.76 | 0.76 |
| 396.32 | 5.10 | 5.10 |
| 240.26 | 2.11 | 2.11 |
| 402.45 | 4.04 | 4.04 |
| 347.33 | 3.55 | 3.55 |
| 240.26 | 2.04 | 2.04 |
| 529.16 | 5.53 | 5.53 |
| 502.47 | 6.00 | 6.00 |
| 408.46 | 1.80 | 1.80 |
| 370.47 | 4.04 | 4.04 |
| 226.24 | 1.65 | 1.65 |
| 288.31 | 3.22 | 3.22 |
| 300.47 | 5.34 | 5.34 |
| 430.56 | 5.24 | 5.24 |
| 333.30 | 3.25 | 3.25 |
| 414.87 | 2.37 | 2.37 |
| 396.45 | 2.97 | 2.97 |
| 356.40 | 2.15 | 2.15 |
| 368.50 | 3.80 | 3.80 |
| 338.40 | 4.24 | 4.24 |
| 383.36 | 4.41 | 4.41 |
| 340.34 | 1.99 | 1.99 |
| 371.44 | 4.97 | 4.97 |
| 374.49 | 3.13 | 3.13 |
| 388.25 | 3.92 | 3.92 |
| 254.72 | 2.24 | 2.24 |
| 294.26 | 1.10 | 1.10 |
| 345.46 | 4.16 | 4.16 |
| 278.72 | 3.88 | 3.88 |
| 478.67 | 3.37 | 3.37 |
| 320.31 | 1.91 | 1.91 |
| 293.41 | 4.22 | 4.22 |
| 333.30 | 2.94 | 2.94 |
| 294.69 | 2.16 | 2.16 |
| 251.24 | 3.05 | 3.05 |
| 309.42 | 4.37 | 4.37 |
| 202.21 | 2.02 | 2.02 |
| 349.35 | 4.80 | 4.80 |
| 354.36 | 2.38 | 2.38 |
| 502.47 | 6.00 | 6.00 |
| 348.42 | 2.97 | 2.97 |
| 247.30 | 3.40 | 3.40 |
| 293.28 | 2.93 | 2.93 |
| 391.90 | 4.46 | 4.46 |
| 398.85 | 4.05 | 4.05 |
| 404.30 | 4.22 | 4.22 |
| 396.87 | 4.57 | 4.57 |
| 562.62 | 5.36 | 5.36 |
| 410.38 | 3.71 | 3.71 |
| 386.88 | 3.13 | 3.13 |
| 376.32 | 3.47 | 3.47 |
| 321.42 | 3.52 | 3.52 |
| 372.42 | 4.34 | 4.34 |
| 422.54 | 5.58 | 5.58 |
| 432.57 | 5.32 | 5.32 |
| 281.36 | 2.68 | 2.68 |
| 288.30 | 4.27 | 4.27 |
| 254.72 | 4.63 | 4.63 |
| 364.28 | 3.33 | 3.33 |
| 571.58 | 0.60 | 0.60 |
| 277.71 | 2.43 | 2.43 |
| 440.54 | 1.23 | 1.23 |
| 358.83 | 2.12 | 2.12 |
| 372.90 | 3.03 | 3.03 |
| 377.43 | 3.29 | 3.29 |
| 418.58 | 4.99 | 4.99 |
| 555.58 | 1.63 | 1.63 |
| 296.20 | 1.98 | 1.98 |
| 359.86 | 2.69 | 2.69 |
| 285.09 | 1.74 | 1.74 |
| 305.34 | 3.09 | 3.09 |
| 368.34 | 2.77 | 2.77 |
| 423.52 | 1.66 | 1.66 |
| 400.91 | 3.29 | 3.29 |
| 266.21 | 0.21 | 0.21 |
| 336.82 | 5.05 | 5.05 |
| 373.41 | 4.25 | 4.25 |
| 421.25 | 3.55 | 3.55 |
| 538.63 | 3.54 | 3.54 |
| 358.44 | 4.80 | 4.80 |
| 378.46 | 3.54 | 3.54 |
| 362.39 | 3.16 | 3.16 |
| 879.86 | 6.39 | 6.39 |
| 649.62 | 7.07 | 7.07 |
| 483.59 | 4.68 | 4.68 |
| 571.72 | 3.97 | 3.97 |
| 573.74 | 3.87 | 3.87 |
| 470.54 | 4.19 | 4.19 |
| 741.18 | 7.38 | 7.38 |
| 482.58 | 4.06 | 4.06 |
| 394.45 | 2.40 | 2.40 |
| 520.70 | 4.76 | 4.76 |
| 453.49 | 3.32 | 3.32 |
| 482.02 | 4.65 | 4.65 |
| 463.53 | 3.90 | 3.90 |
| 470.54 | 4.19 | 4.19 |
| 634.63 | 5.38 | 5.38 |
| 465.60 | 4.54 | 4.54 |
| 450.54 | 2.83 | 2.83 |
| 456.51 | 4.17 | 4.17 |
| 450.56 | 3.50 | 3.50 |
| 659.81 | 5.64 | 5.64 |
| 438.52 | 3.63 | 3.63 |
| 420.50 | 4.18 | 4.18 |
| 434.56 | 3.80 | 3.80 |
| 422.50 | 3.18 | 3.18 |
| 466.65 | 3.76 | 3.76 |
| 447.55 | 4.04 | 4.04 |
| 357.46 | 3.29 | 3.29 |