Basic Information
ID: ALA3214812
Type: Binding
Description: PubChem BioAssay. Fluorescence-based biochemical high throughput screening dose response assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214812
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.32 | 4.13 | 4.13 |
| 355.43 | 3.47 | 3.47 |
| 208.22 | 2.73 | 2.73 |
| 249.27 | 2.91 | 2.91 |
| 520.50 | 3.30 | 3.30 |
| 357.35 | 2.78 | 2.78 |
| 375.85 | 3.86 | 3.86 |
| 384.45 | 6.46 | 6.46 |
| 272.31 | 3.66 | 3.66 |
| 174.16 | 0.15 | 0.15 |
| 259.74 | 1.98 | 1.98 |
| 280.33 | 2.29 | 2.29 |
| 328.35 | 1.55 | 1.55 |
| 210.19 | 1.52 | 1.52 |
| 310.40 | 1.73 | 1.73 |
| 579.99 | 0.00 | 0.00 |
| 366.39 | 3.47 | 3.47 |
| 395.41 | 2.78 | 2.78 |
| 346.43 | 4.18 | 4.18 |
| 332.40 | 3.88 | 3.88 |
| 309.33 | 1.03 | 1.03 |
| 249.70 | 3.20 | 3.20 |
| 410.39 | 3.49 | 3.49 |
| 410.39 | 3.49 | 3.49 |
| 290.75 | 1.76 | 1.76 |
| 161.16 | 0.50 | 0.50 |
| 302.28 | 1.72 | 1.72 |
| 327.38 | 2.77 | 2.77 |
| 355.19 | 4.28 | 4.28 |
| 448.94 | 5.09 | 5.09 |
| 369.76 | 3.27 | 3.27 |
| 452.54 | 4.36 | 4.36 |
| 386.50 | 3.51 | 3.51 |
| 334.41 | 1.17 | 1.17 |
| 300.32 | 2.61 | 2.61 |
| 388.42 | 2.80 | 2.80 |
| 452.55 | 2.36 | 2.36 |
| 424.50 | 3.61 | 3.61 |
| 434.45 | 3.43 | 3.43 |
| 190.16 | 1.85 | 1.85 |
| 357.37 | 3.51 | 3.51 |
| 331.47 | 3.48 | 3.48 |
| 468.35 | 4.29 | 4.29 |
| 265.31 | 2.45 | 2.45 |
| 500.51 | 3.87 | 3.87 |
| 398.47 | 3.62 | 3.62 |
| 306.32 | 2.29 | 2.29 |
| 375.38 | 3.30 | 3.30 |
| 256.21 | 2.06 | 2.06 |
| 311.34 | 1.59 | 1.59 |
| 369.36 | 1.33 | 1.33 |
| 307.35 | 3.25 | 3.25 |
| 442.33 | 5.55 | 5.55 |
| 348.40 | 3.03 | 3.03 |
| 390.20 | 3.46 | 3.46 |
| 862.75 | -1.10 | -1.10 |
| 263.30 | 3.21 | 3.21 |
| 369.43 | 4.68 | 4.68 |
| 266.32 | 2.68 | 2.68 |
| 441.55 | 3.63 | 3.63 |
| 410.83 | 3.58 | 3.58 |
| 291.65 | 2.92 | 2.92 |
| 341.73 | 2.50 | 2.50 |
| 452.56 | 4.34 | 4.34 |
| 283.28 | 2.55 | 2.55 |
| 483.55 | 2.34 | 2.34 |
| 290.42 | 3.06 | 3.06 |
| 546.67 | 5.72 | 5.72 |
| 302.36 | 3.63 | 3.63 |
| 316.41 | 3.73 | 3.73 |
| 241.29 | 2.28 | 2.28 |
| 437.30 | 3.30 | 3.30 |
| 210.62 | 1.03 | 1.03 |
| 300.31 | 2.78 | 2.78 |
| 534.66 | 5.33 | 5.33 |
| 363.37 | 3.26 | 3.26 |
| 265.27 | 3.44 | 3.44 |
| 404.33 | 4.18 | 4.18 |
| 410.45 | 1.48 | 1.48 |
| 334.83 | 6.05 | 6.05 |
| 177.20 | 0.74 | 0.74 |
| 434.59 | 5.16 | 5.16 |
| 213.28 | 3.31 | 3.31 |
| 362.41 | 0.53 | 0.53 |
| 481.51 | 7.61 | 7.61 |
| 360.37 | 2.01 | 2.01 |
| 387.45 | 5.79 | 5.79 |
| 356.42 | 3.02 | 3.02 |
| 263.30 | 2.58 | 2.58 |
| 310.27 | 3.44 | 3.44 |
| 315.17 | 4.45 | 4.45 |
| 243.26 | 1.13 | 1.13 |
| 330.44 | 4.12 | 4.12 |
| 385.38 | 1.10 | 1.10 |
| 240.35 | 1.63 | 1.63 |
| 270.25 | -0.56 | -0.56 |
| 336.33 | 2.46 | 2.46 |
| 251.29 | 2.41 | 2.41 |
| 392.84 | 3.44 | 3.44 |
| 252.07 | 1.63 | 1.63 |
| 250.30 | 3.55 | 3.55 |
| 489.33 | 4.44 | 4.44 |
| 398.37 | 3.41 | 3.41 |
| 380.29 | 3.65 | 3.65 |
| 331.31 | 3.06 | 3.06 |
| 396.38 | 2.48 | 2.48 |
| 324.29 | 2.59 | 2.59 |
| 296.37 | 3.51 | 3.51 |
| 378.38 | 2.42 | 2.42 |
| 353.76 | 1.62 | 1.62 |
| 411.44 | 3.17 | 3.17 |
| 278.29 | -0.01 | -0.01 |
| 521.61 | 4.16 | 4.16 |
| 352.35 | 2.39 | 2.39 |
| 436.35 | 3.47 | 3.47 |
| 323.74 | 2.25 | 2.25 |
| 292.43 | 3.26 | 3.26 |
| 313.81 | 4.70 | 4.70 |
| 306.30 | 2.45 | 2.45 |
| 281.31 | 2.42 | 2.42 |
| 408.46 | 3.31 | 3.31 |
| 218.26 | 1.80 | 1.80 |
| 409.73 | 3.52 | 3.52 |
| 256.30 | 2.45 | 2.45 |
| 507.50 | 6.38 | 6.38 |
| 297.75 | 2.76 | 2.76 |
| 321.41 | 4.47 | 4.47 |
| 372.28 | 2.86 | 2.86 |
| 261.28 | 1.68 | 1.68 |
| 331.80 | 3.70 | 3.70 |
| 251.24 | 3.05 | 3.05 |
| 297.27 | 2.16 | 2.16 |
| 343.43 | 3.55 | 3.55 |
| 359.35 | 2.30 | 2.30 |
| 278.38 | 3.34 | 3.34 |
| 376.41 | 2.92 | 2.92 |
| 424.48 | 1.83 | 1.83 |
| 325.32 | 1.84 | 1.84 |
| 442.95 | 5.00 | 5.00 |
| 369.43 | 4.51 | 4.51 |
| 423.90 | 4.18 | 4.18 |
| 509.82 | 4.61 | 4.61 |
| 327.47 | 4.36 | 4.36 |
| 338.32 | 2.27 | 2.27 |
| 214.18 | 1.79 | 1.79 |
| 424.46 | 3.99 | 3.99 |
| 367.49 | 5.03 | 5.03 |
| 340.40 | 2.75 | 2.75 |
| 432.27 | 4.26 | 4.26 |
| 302.29 | 3.29 | 3.29 |
| 417.51 | 4.09 | 4.09 |
| 264.32 | 3.97 | 3.97 |
| 308.34 | 2.74 | 2.74 |
| 574.58 | 4.16 | 4.16 |
| 288.31 | 3.70 | 3.70 |
| 477.74 | 0.71 | 0.71 |
| 259.34 | 1.29 | 1.29 |
| 218.21 | 0.59 | 0.59 |
| 254.25 | 2.20 | 2.20 |
| 389.24 | 0.54 | 0.54 |
| 282.09 | 2.02 | 2.02 |
| 191.14 | 0.45 | 0.45 |
| 543.57 | 3.90 | 3.90 |
| 487.97 | 2.92 | 2.92 |
| 402.46 | 6.46 | 6.46 |
| 303.41 | 3.18 | 3.18 |
| 258.30 | 1.39 | 1.39 |
| 256.33 | 2.83 | 2.83 |
| 175.19 | 1.65 | 1.65 |
| 484.50 | 4.13 | 4.13 |
| 277.28 | 2.38 | 2.38 |
| 345.20 | 4.46 | 4.46 |
| 296.20 | 1.98 | 1.98 |
| 280.12 | 3.14 | 3.14 |
| 289.13 | 3.44 | 3.44 |
| 529.50 | 4.04 | 4.04 |
| 523.53 | 2.71 | 2.71 |
| 255.23 | 1.12 | 1.12 |
| 324.34 | 2.57 | 2.57 |
| 230.18 | 1.32 | 1.32 |
| 294.38 | 4.27 | 4.27 |
| 373.41 | 4.07 | 4.07 |
| 286.70 | 0.12 | 0.12 |
| 305.76 | 2.63 | 2.63 |
| 253.06 | 1.03 | 1.03 |
| 264.27 | 1.68 | 1.68 |
| 438.49 | 3.82 | 3.82 |
| 240.23 | 2.47 | 2.47 |
| 199.21 | 1.11 | 1.11 |
| 413.56 | 5.27 | 5.27 |
| 436.51 | 3.61 | 3.61 |
| 304.37 | 3.81 | 3.81 |
| 460.51 | 4.37 | 4.37 |
| 453.91 | 3.46 | 3.46 |
| 446.48 | 4.06 | 4.06 |
| 346.39 | 2.28 | 2.28 |
| 305.36 | 4.30 | 4.30 |
| 300.27 | 1.17 | 1.17 |
| 348.40 | 4.07 | 4.07 |
| 432.46 | 3.76 | 3.76 |
| 446.48 | 4.06 | 4.06 |
| 310.38 | 3.65 | 3.65 |
| 359.39 | 3.51 | 3.51 |
| 358.01 | 6.46 | 6.46 |
| 450.45 | 3.89 | 3.89 |
| 368.48 | 3.96 | 3.96 |
| 230.27 | 2.17 | 2.17 |
| 353.38 | 2.89 | 2.89 |
| 576.82 | 5.79 | 5.79 |
| 478.55 | 5.97 | 5.97 |
| 408.50 | 4.43 | 4.43 |
| 290.28 | 1.21 | 1.21 |
| 460.51 | 4.32 | 4.32 |
| 423.89 | 3.45 | 3.45 |
| 384.40 | 2.15 | 2.15 |
| 434.47 | 3.77 | 3.77 |
| 419.47 | 2.80 | 2.80 |
| 341.32 | 3.06 | 3.06 |
| 293.28 | 2.60 | 2.60 |
| 548.60 | 3.18 | 3.18 |
| 408.50 | 4.43 | 4.43 |
| 474.54 | 4.68 | 4.68 |
| 310.38 | 3.65 | 3.65 |
| 293.75 | 2.53 | 2.53 |
| 265.70 | 1.49 | 1.49 |
| 332.28 | 2.78 | 2.78 |