Basic Information
ID: ALA3214817
Type: Binding
Description: PubChem BioAssay. Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214817
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.49 | -0.14 | -0.14 |
| 403.98 | 3.94 | 3.94 |
| 505.46 | 4.18 | 4.18 |
| 405.97 | 6.56 | 6.56 |
| 418.28 | 3.92 | 3.92 |
| 493.55 | 3.65 | 3.65 |
| 532.47 | 4.46 | 4.46 |
| 219.33 | 1.16 | 1.16 |
| 319.86 | 2.50 | 2.50 |
| 343.38 | 2.39 | 2.39 |
| 354.36 | 3.79 | 3.79 |
| 327.43 | 5.95 | 5.95 |
| 506.48 | 6.09 | 6.09 |
| 475.63 | 5.11 | 5.11 |
| 365.83 | 3.33 | 3.33 |
| 355.33 | 4.89 | 4.89 |
| 488.41 | 5.17 | 5.17 |
| 337.43 | 5.52 | 5.52 |
| 266.77 | 3.24 | 3.24 |
| 350.42 | 3.95 | 3.95 |
| 681.78 | 6.94 | 6.94 |
| 314.39 | 5.53 | 5.53 |
| 406.46 | 2.13 | 2.13 |
| 407.05 | 5.89 | 5.89 |
| 564.15 | 4.58 | 4.58 |
| 214.26 | 1.09 | 1.09 |
| 534.06 | 5.03 | 5.03 |
| 527.57 | 4.20 | 4.20 |
| 529.69 | 4.69 | 4.69 |
| 285.26 | 2.55 | 2.55 |
| 368.87 | 3.33 | 3.33 |
| 307.37 | 2.78 | 2.78 |
| 437.50 | 4.31 | 4.31 |
| 460.57 | 3.97 | 3.97 |
| 342.40 | 4.24 | 4.24 |
| 254.33 | 5.04 | 5.04 |
| 446.78 | 4.69 | 4.69 |
| 572.75 | 6.47 | 6.47 |
| 344.37 | 4.18 | 4.18 |
| 500.51 | 3.87 | 3.87 |
| 470.05 | 5.85 | 5.85 |
| 398.55 | 4.48 | 4.48 |
| 353.42 | 3.57 | 3.57 |
| 437.57 | 4.00 | 4.00 |
| 371.87 | 4.14 | 4.14 |
| 371.82 | 1.59 | 1.59 |
| 290.37 | 3.40 | 3.40 |
| 345.45 | 3.33 | 3.33 |
| 514.67 | 6.41 | 6.41 |
| 430.91 | 3.40 | 3.40 |
| 438.67 | 6.28 | 6.28 |
| 388.51 | 4.38 | 4.38 |
| 527.62 | 6.21 | 6.21 |
| 435.88 | 4.95 | 4.95 |
| 340.51 | 4.68 | 4.68 |
| 538.65 | 4.59 | 4.59 |
| 422.96 | 5.09 | 5.09 |
| 295.29 | 2.74 | 2.74 |
| 546.67 | 4.61 | 4.61 |
| 458.07 | 5.39 | 5.39 |
| 323.48 | 5.15 | 5.15 |
| 287.37 | 3.80 | 3.80 |
| 285.26 | 2.55 | 2.55 |
| 350.51 | 5.25 | 5.25 |
| 317.43 | 3.26 | 3.26 |
| 314.39 | 4.76 | 4.76 |
| 205.31 | 1.41 | 1.41 |
| 339.35 | 3.46 | 3.46 |
| 550.30 | 4.16 | 4.16 |
| 340.47 | 2.15 | 2.15 |
| 534.68 | 4.15 | 4.15 |
| 223.63 | 0.23 | 0.23 |
| 388.31 | 5.47 | 5.47 |
| 402.33 | 4.58 | 4.58 |
| 943.64 | 1.87 | 1.87 |
| 335.75 | 3.69 | 3.69 |
| 409.57 | 3.97 | 3.97 |
| 338.36 | 1.98 | 1.98 |
| 257.36 | 2.94 | 2.94 |
| 470.87 | 3.71 | 3.71 |
| 232.29 | 5.21 | 5.21 |
| 351.28 | 3.08 | 3.08 |
| 327.45 | 4.87 | 4.87 |
| 336.27 | 3.00 | 3.00 |
| 341.81 | 3.44 | 3.44 |
| 386.50 | 1.70 | 1.70 |
| 488.05 | 4.35 | 4.35 |
| 540.70 | 6.80 | 6.80 |
| 255.79 | 1.72 | 1.72 |
| 262.18 | 1.67 | 1.67 |
| 495.51 | -0.36 | -0.36 |
| 517.41 | -0.14 | -0.14 |
| 348.86 | 5.00 | 5.00 |
| 474.03 | 4.50 | 4.50 |
| 472.51 | 1.45 | 1.45 |
| 349.42 | 4.30 | 4.30 |
| 225.25 | 2.37 | 2.37 |
| 420.47 | 2.77 | 2.77 |
| 551.76 | 4.55 | 4.55 |
| 384.52 | 4.09 | 4.09 |
| 366.41 | 1.91 | 1.91 |
| 283.38 | 3.65 | 3.65 |
| 387.36 | 1.68 | 1.68 |
| 447.41 | 2.65 | 2.65 |
| 316.83 | 3.56 | 3.56 |
| 551.62 | 1.06 | 1.06 |
| 573.73 | 5.13 | 5.13 |
| 226.32 | 4.25 | 4.25 |
| 445.44 | 3.33 | 3.33 |
| 510.06 | 5.13 | 5.13 |
| 267.35 | 4.48 | 4.48 |
| 432.61 | 5.86 | 5.86 |
| 462.02 | 4.28 | 4.28 |
| 344.41 | 3.74 | 3.74 |
| 601.19 | 5.04 | 5.04 |
| 486.04 | 5.07 | 5.07 |
| 404.55 | 5.08 | 5.08 |
| 459.97 | 4.81 | 4.81 |
| 422.53 | 6.09 | 6.09 |
| 190.29 | 3.01 | 3.01 |
| 380.29 | 3.65 | 3.65 |
| 290.08 | 3.29 | 3.29 |
| 378.43 | 3.80 | 3.80 |
| 419.52 | 3.74 | 3.74 |
| 513.59 | 5.82 | 5.82 |
| 971.66 | 0.65 | 0.65 |
| 388.85 | 3.90 | 3.90 |
| 464.61 | 5.13 | 5.13 |
| 346.81 | 4.02 | 4.02 |
| 373.38 | 3.74 | 3.74 |
| 367.24 | 2.57 | 2.57 |
| 416.95 | 4.47 | 4.47 |
| 306.32 | 1.68 | 1.68 |
| 251.29 | 2.53 | 2.53 |
| 430.33 | 4.38 | 4.38 |
| 524.09 | 5.52 | 5.52 |
| 290.32 | 3.64 | 3.64 |
| 565.79 | 4.94 | 4.94 |
| 417.46 | 3.39 | 3.39 |
| 355.46 | 4.22 | 4.22 |
| 262.31 | 5.27 | 5.27 |
| 194.30 | 2.57 | 2.57 |
| 411.53 | 3.06 | 3.06 |
| 353.85 | 4.56 | 4.56 |
| 547.50 | 4.40 | 4.40 |
| 401.43 | 4.30 | 4.30 |
| 506.69 | 6.23 | 6.23 |
| 508.09 | 5.69 | 5.69 |
| 338.36 | 1.98 | 1.98 |
| 348.49 | 4.85 | 4.85 |
| 465.69 | 5.31 | 5.31 |
| 304.19 | 4.93 | 4.93 |
| 420.92 | 4.52 | 4.52 |
| 579.82 | 5.33 | 5.33 |
| 620.74 | 5.09 | 5.09 |
| 312.11 | 5.02 | 5.02 |
| 380.54 | 4.31 | 4.31 |
| 403.56 | 4.76 | 4.76 |
| 405.59 | 4.98 | 4.98 |
| 477.00 | 3.14 | 3.14 |
| 350.45 | 3.60 | 3.60 |
| 253.28 | 5.03 | 5.03 |
| 395.38 | 5.56 | 5.56 |
| 579.82 | 5.33 | 5.33 |
| 309.32 | 3.04 | 3.04 |
| 315.81 | 3.02 | 3.02 |
| 1001.73 | 1.28 | 1.28 |
| 330.39 | 5.15 | 5.15 |
| 363.46 | 4.01 | 4.01 |
| 325.78 | 1.47 | 1.47 |
| 297.31 | 2.90 | 2.90 |
| 360.41 | 2.05 | 2.05 |
| 467.57 | 1.42 | 1.42 |
| 434.95 | 5.00 | 5.00 |
| 293.37 | 3.61 | 3.61 |
| 449.45 | 5.43 | 5.43 |
| 393.42 | 4.61 | 4.61 |
| 310.44 | 4.87 | 4.87 |
| 376.97 | 4.07 | 4.07 |
| 368.23 | 3.88 | 3.88 |
| 304.31 | 3.39 | 3.39 |
| 322.36 | 2.28 | 2.28 |
| 433.53 | 3.86 | 3.86 |
| 523.13 | 6.48 | 6.48 |
| 338.84 | 4.78 | 4.78 |
| 360.41 | 5.16 | 5.16 |
| 410.56 | 3.65 | 3.65 |
| 421.59 | 2.79 | 2.79 |
| 463.46 | 3.29 | 3.29 |
| 548.68 | 5.01 | 5.01 |
| 406.47 | 2.60 | 2.60 |
| 321.42 | 4.11 | 4.11 |
| 491.54 | 2.45 | 2.45 |
| 348.88 | 4.80 | 4.80 |
| 317.43 | 3.21 | 3.21 |
| 328.44 | 4.65 | 4.65 |
| 254.38 | 3.41 | 3.41 |
| 492.15 | 6.80 | 6.80 |
| 574.58 | 4.16 | 4.16 |
| 386.54 | 2.85 | 2.85 |
| 425.53 | 4.13 | 4.13 |
| 460.92 | 4.67 | 4.67 |
| 359.54 | 3.02 | 3.02 |
| 296.33 | 2.49 | 2.49 |
| 937.17 | -1.38 | -1.38 |
| 543.57 | 3.90 | 3.90 |
| 239.32 | 2.98 | 2.98 |
| 459.61 | 6.73 | 6.73 |
| 303.41 | 3.18 | 3.18 |
| 256.33 | 2.83 | 2.83 |
| 517.46 | 3.94 | 3.94 |
| 501.03 | 3.18 | 3.18 |
| 557.59 | 4.21 | 4.21 |
| 419.92 | -0.03 | -0.03 |
| 412.49 | 0.45 | 0.45 |
| 370.32 | 5.33 | 5.33 |
| 480.59 | 4.64 | 4.64 |
| 501.53 | 3.68 | 3.68 |
| 441.98 | 4.64 | 4.64 |
| 714.56 | 3.55 | 3.55 |
| 284.39 | 4.29 | 4.29 |
| 674.77 | 6.57 | 6.57 |
| 557.59 | 4.21 | 4.21 |
| 678.15 | 6.44 | 6.44 |
| 967.15 | -3.06 | -3.06 |
| 446.02 | 4.39 | 4.39 |
| 566.68 | 4.10 | 4.10 |
| 330.86 | 3.51 | 3.51 |
| 400.91 | 3.29 | 3.29 |
| 993.28 | 0.20 | 0.20 |
| 471.55 | 3.67 | 3.67 |
| 594.76 | 5.55 | 5.55 |
| 482.65 | 5.95 | 5.95 |
| 453.55 | 4.03 | 4.03 |
| 421.55 | 4.02 | 4.02 |
| 355.78 | 3.58 | 3.58 |
| 495.51 | 4.55 | 4.55 |
| 389.54 | 4.03 | 4.03 |
| 308.47 | 5.17 | 5.17 |
| 524.71 | 4.99 | 4.99 |
| 343.45 | 2.50 | 2.50 |
| 318.42 | 4.72 | 4.72 |
| 594.62 | 5.99 | 5.99 |
| 261.33 | 3.56 | 3.56 |
| 417.60 | 3.00 | 3.00 |
| 479.56 | 3.62 | 3.62 |
| 457.53 | 3.54 | 3.54 |
| 495.51 | 4.55 | 4.55 |
| 487.63 | 4.64 | 4.64 |
| 539.65 | 3.78 | 3.78 |
| 385.28 | 3.22 | 3.22 |
| 281.28 | 3.13 | 3.13 |
| 375.41 | 2.36 | 2.36 |
| 474.54 | 2.83 | 2.83 |
| 348.79 | 3.09 | 3.09 |
| 540.23 | 5.32 | 5.32 |
| 358.47 | 3.03 | 3.03 |
| 335.41 | 3.24 | 3.24 |
| 517.67 | 4.90 | 4.90 |
| 531.70 | 4.83 | 4.83 |
| 425.54 | 4.38 | 4.38 |
| 396.58 | 6.19 | 6.19 |
| 543.63 | 4.01 | 4.01 |
| 413.52 | 1.85 | 1.85 |
| 373.40 | 2.42 | 2.42 |
| 425.55 | 1.67 | 1.67 |
| 593.73 | 5.70 | 5.70 |
| 466.56 | 3.87 | 3.87 |
| 482.02 | 4.65 | 4.65 |
| 290.44 | 2.94 | 2.94 |
| 494.46 | 4.41 | 4.41 |
| 418.51 | 4.85 | 4.85 |
| 594.62 | 5.99 | 5.99 |
| 360.46 | 2.40 | 2.40 |
| 444.54 | 5.03 | 5.03 |
| 508.49 | 4.34 | 4.34 |
| 500.60 | 4.26 | 4.26 |
| 439.52 | 3.48 | 3.48 |
| 496.05 | 4.66 | 4.66 |
| 596.77 | 5.16 | 5.16 |
| 439.52 | 3.48 | 3.48 |
| 596.77 | 5.16 | 5.16 |
| 531.78 | 5.06 | 5.06 |
| 660.81 | 5.99 | 5.99 |
| 480.63 | 2.07 | 2.07 |
| 501.67 | 4.77 | 4.77 |
| 515.70 | 4.70 | 4.70 |
| 508.49 | 4.34 | 4.34 |
| 349.39 | 3.51 | 3.51 |
| 295.39 | 2.32 | 2.32 |
| 227.31 | 2.84 | 2.84 |
| 297.36 | 2.09 | 2.09 |
| 251.29 | 2.79 | 2.79 |
| 434.47 | 3.77 | 3.77 |
| 388.42 | 4.04 | 4.04 |
| 344.37 | 3.80 | 3.80 |
| 343.39 | 3.36 | 3.36 |
| 259.31 | 3.08 | 3.08 |
| 377.31 | 4.17 | 4.17 |
| 304.37 | 2.87 | 2.87 |
| 389.53 | 4.75 | 4.75 |
| 319.45 | 4.77 | 4.77 |
| 407.33 | 3.11 | 3.11 |
| 249.36 | 2.74 | 2.74 |
| 371.20 | 3.52 | 3.52 |
| 975.12 | 4.70 | 4.70 |