ID: ALA3214851
Type: Binding
Description: PubChem BioAssay. Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen. (Class of assay: confirmatory)
Bioactivity
Activity Types for Assay ALA3214851
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
254.33 | 2.03 | 2.03 |
375.47 | 3.69 | 3.69 |
298.29 | 3.18 | 3.18 |
462.98 | 5.25 | 5.25 |
442.49 | 2.61 | 2.61 |
502.58 | 2.01 | 2.01 |
341.37 | 2.32 | 2.32 |
412.87 | 5.61 | 5.61 |
329.35 | 1.86 | 1.86 |
364.40 | 3.52 | 3.52 |
399.48 | 2.19 | 2.19 |
345.35 | 2.17 | 2.17 |
326.40 | 4.49 | 4.49 |
330.41 | 2.43 | 2.43 |
407.47 | 2.15 | 2.15 |
328.38 | 3.95 | 3.95 |
319.39 | 1.25 | 1.25 |
310.36 | 3.17 | 3.17 |
407.47 | 1.98 | 1.98 |
341.44 | 3.03 | 3.03 |
244.19 | 1.61 | 1.61 |
532.59 | 4.10 | 4.10 |
416.49 | 2.41 | 2.41 |
345.40 | 3.50 | 3.50 |
469.56 | 3.89 | 3.89 |
373.32 | 1.39 | 1.39 |
414.30 | 4.83 | 4.83 |
335.14 | 1.02 | 1.02 |
296.33 | 1.98 | 1.98 |
317.35 | 2.50 | 2.50 |
315.40 | 2.75 | 2.75 |
399.43 | 1.61 | 1.61 |
282.30 | 2.64 | 2.64 |
423.47 | 3.95 | 3.95 |
330.43 | 3.69 | 3.69 |
397.23 | 4.31 | 4.31 |
350.42 | 3.95 | 3.95 |
359.42 | 2.51 | 2.51 |
367.43 | 3.95 | 3.95 |
392.43 | 5.48 | 5.48 |
369.42 | 4.14 | 4.14 |
316.40 | 3.30 | 3.30 |
318.37 | 3.30 | 3.30 |
367.47 | 2.71 | 2.71 |
363.46 | 4.54 | 4.54 |
302.34 | 3.47 | 3.47 |
363.44 | 2.44 | 2.44 |
304.35 | 4.05 | 4.05 |
481.60 | 2.26 | 2.26 |
367.45 | 2.83 | 2.83 |
324.33 | 3.40 | 3.40 |
393.42 | 3.14 | 3.14 |
294.36 | 2.85 | 2.85 |
355.42 | 2.94 | 2.94 |
356.38 | 3.97 | 3.97 |
387.39 | 3.40 | 3.40 |
337.38 | 3.00 | 3.00 |
368.39 | 5.21 | 5.21 |
278.23 | 3.82 | 3.82 |
421.38 | 2.75 | 2.75 |
351.41 | 2.95 | 2.95 |
378.47 | 3.45 | 3.45 |
428.33 | 5.22 | 5.22 |
283.40 | 3.78 | 3.78 |
274.11 | 1.07 | 1.07 |
365.24 | 2.53 | 2.53 |
416.27 | 3.76 | 3.76 |
321.43 | 3.29 | 3.29 |
338.41 | 2.77 | 2.77 |
343.41 | 2.02 | 2.02 |
193.21 | 2.36 | 2.36 |
332.33 | 4.01 | 4.01 |
310.25 | 3.35 | 3.35 |
277.30 | 1.82 | 1.82 |
297.38 | 3.34 | 3.34 |
328.42 | 4.31 | 4.31 |
366.44 | 4.19 | 4.19 |
270.31 | 3.05 | 3.05 |
378.47 | 3.38 | 3.38 |
399.44 | 3.77 | 3.77 |
319.37 | 3.05 | 3.05 |
465.50 | 3.40 | 3.40 |
257.12 | 3.12 | 3.12 |
358.46 | 3.18 | 3.18 |
427.51 | 1.06 | 1.06 |
437.50 | 2.05 | 2.05 |
296.35 | 3.89 | 3.89 |
319.34 | 3.99 | 3.99 |
448.98 | 6.21 | 6.21 |
346.79 | 0.38 | 0.38 |
381.41 | 3.42 | 3.42 |
382.49 | 2.68 | 2.68 |
353.30 | 2.63 | 2.63 |
401.46 | 3.15 | 3.15 |
284.36 | 3.26 | 3.26 |
274.68 | 3.79 | 3.79 |
340.43 | 1.95 | 1.95 |
341.44 | 3.36 | 3.36 |
405.48 | 3.32 | 3.32 |
360.81 | 1.04 | 1.04 |
293.16 | 3.70 | 3.70 |
440.54 | 4.01 | 4.01 |
346.46 | 4.93 | 4.93 |
333.44 | 3.15 | 3.15 |
401.40 | 2.82 | 2.82 |
427.50 | 5.61 | 5.61 |
369.45 | 2.51 | 2.51 |
408.45 | 3.30 | 3.30 |
343.21 | 3.22 | 3.22 |
414.49 | 2.36 | 2.36 |
379.46 | 4.55 | 4.55 |
384.86 | 3.57 | 3.57 |
261.32 | 2.44 | 2.44 |
336.39 | 3.53 | 3.53 |
374.44 | 3.98 | 3.98 |
368.39 | 5.13 | 5.13 |
314.30 | 3.20 | 3.20 |
363.46 | 4.93 | 4.93 |
429.52 | 1.58 | 1.58 |
329.31 | 1.74 | 1.74 |
236.28 | 2.71 | 2.71 |
309.37 | 2.64 | 2.64 |
388.54 | 2.77 | 2.77 |
322.16 | 2.37 | 2.37 |
416.89 | 4.68 | 4.68 |
377.42 | 1.73 | 1.73 |
468.56 | 0.93 | 0.93 |
457.48 | 2.33 | 2.33 |
427.50 | 4.47 | 4.47 |
402.54 | 4.55 | 4.55 |
377.45 | 1.13 | 1.13 |
316.40 | 3.30 | 3.30 |
325.42 | 4.47 | 4.47 |
299.33 | 4.04 | 4.04 |
463.91 | 2.83 | 2.83 |
263.30 | 3.19 | 3.19 |
465.51 | 4.52 | 4.52 |
352.39 | 3.52 | 3.52 |
230.31 | 3.02 | 3.02 |
445.51 | 3.51 | 3.51 |
448.55 | 3.96 | 3.96 |
296.33 | 2.64 | 2.64 |
295.32 | 4.04 | 4.04 |
528.58 | 4.45 | 4.45 |
364.45 | 3.06 | 3.06 |
386.57 | 4.66 | 4.66 |
333.30 | 3.67 | 3.67 |
303.16 | 3.30 | 3.30 |
354.41 | 2.85 | 2.85 |
428.50 | 2.06 | 2.06 |
369.43 | 1.55 | 1.55 |
392.41 | 2.40 | 2.40 |
383.35 | 4.57 | 4.57 |
357.34 | 2.29 | 2.29 |
257.32 | 3.25 | 3.25 |
385.47 | 4.44 | 4.44 |
324.43 | 3.86 | 3.86 |
293.37 | 4.05 | 4.05 |
315.38 | 2.04 | 2.04 |
324.34 | 3.99 | 3.99 |
423.40 | 2.46 | 2.46 |
279.34 | 2.40 | 2.40 |
390.44 | 2.11 | 2.11 |
321.31 | 3.43 | 3.43 |
293.33 | 3.10 | 3.10 |
401.41 | 2.86 | 2.86 |
311.34 | 2.65 | 2.65 |
309.33 | 3.41 | 3.41 |
425.47 | 2.76 | 2.76 |
361.45 | 2.56 | 2.56 |
248.71 | 3.03 | 3.03 |
238.31 | 2.77 | 2.77 |
354.36 | 3.40 | 3.40 |
379.37 | 1.60 | 1.60 |
386.43 | 1.82 | 1.82 |
350.42 | 4.44 | 4.44 |
324.29 | 3.03 | 3.03 |
305.34 | 2.74 | 2.74 |
538.59 | 4.51 | 4.51 |
357.39 | 2.91 | 2.91 |
255.30 | 0.36 | 0.36 |
317.17 | 2.35 | 2.35 |
409.42 | 4.78 | 4.78 |
331.32 | 1.27 | 1.27 |
385.42 | 3.29 | 3.29 |
314.34 | 3.86 | 3.86 |
379.34 | 2.40 | 2.40 |
369.46 | 1.27 | 1.27 |
439.49 | 2.87 | 2.87 |
270.36 | 3.26 | 3.26 |
435.44 | 3.21 | 3.21 |
259.31 | 4.45 | 4.45 |
230.27 | 1.78 | 1.78 |
341.44 | 3.31 | 3.31 |
691.87 | 5.13 | 5.13 |
357.40 | 1.67 | 1.67 |
318.38 | 3.80 | 3.80 |
460.53 | 2.68 | 2.68 |
439.51 | 2.65 | 2.65 |
368.50 | 4.32 | 4.32 |
449.47 | 3.52 | 3.52 |
357.40 | 2.00 | 2.00 |
375.55 | 4.59 | 4.59 |
398.23 | 3.18 | 3.18 |
462.33 | 3.48 | 3.48 |
337.76 | 1.99 | 1.99 |
453.56 | 2.68 | 2.68 |
326.36 | 0.97 | 0.97 |
370.48 | 3.34 | 3.34 |
237.31 | 3.07 | 3.07 |
251.28 | 3.70 | 3.70 |
214.27 | 2.28 | 2.28 |
302.37 | 1.96 | 1.96 |
486.40 | 4.44 | 4.44 |
513.54 | -0.25 | -0.25 |
442.50 | 3.35 | 3.35 |
238.29 | 2.84 | 2.84 |
288.35 | 4.04 | 4.04 |
238.29 | 2.84 | 2.84 |
478.51 | 2.90 | 2.90 |
224.26 | 2.54 | 2.54 |
372.45 | 4.61 | 4.61 |
602.69 | 6.68 | 6.68 |
338.41 | 2.73 | 2.73 |
438.57 | 3.34 | 3.34 |
215.26 | 2.19 | 2.19 |
289.34 | 1.79 | 1.79 |
246.22 | 2.26 | 2.26 |
288.33 | 1.77 | 1.77 |
560.65 | 6.98 | 6.98 |
299.40 | 3.67 | 3.67 |
240.31 | 2.38 | 2.38 |
367.36 | 2.66 | 2.66 |
229.67 | 3.05 | 3.05 |
398.43 | 5.73 | 5.73 |
350.42 | 3.24 | 3.24 |
348.83 | 1.92 | 1.92 |
314.35 | 3.65 | 3.65 |
398.47 | 4.62 | 4.62 |
407.47 | 1.84 | 1.84 |
498.54 | 3.15 | 3.15 |
374.40 | 4.37 | 4.37 |
352.39 | 2.73 | 2.73 |
323.42 | 1.20 | 1.20 |
402.84 | 3.09 | 3.09 |
568.70 | 3.02 | 3.02 |
252.28 | 2.32 | 2.32 |
401.45 | 4.43 | 4.43 |