Basic Information
ID: ALA3214895
Type: Binding
Description: PubChem BioAssay. Counterscreen for inhibitors of 5-meCpG-binding domain protein 2 (MBD2): TRFRET-based biochemical high throughput dose response assay to identify inhibitors of binding of ubiquitin-like with PHD and ring finger domains 1 (UHRF1) to methylated oligonucleotide. (Class of assay: confirmatory)
Format: BAO_0000357
Target: E3 ubiquitin-protein ligase UHRF1(ALA2424510)
Document: ALA1201862
PubChem Source: AID:720644
Activity Charts
Bioactivity
Activity Types for Assay ALA3214895
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.44 | 2.59 | 2.59 |
| 279.34 | 3.17 | 3.17 |
| 339.35 | 2.44 | 2.44 |
| 328.44 | 3.40 | 3.40 |
| 387.94 | 4.63 | 4.63 |
| 220.28 | 2.93 | 2.93 |
| 359.86 | 2.69 | 2.69 |
| 448.94 | 5.09 | 5.09 |
| 389.44 | 2.63 | 2.63 |
| 305.38 | 3.50 | 3.50 |
| 409.49 | 1.94 | 1.94 |
| 215.30 | 2.31 | 2.31 |
| 534.66 | 5.33 | 5.33 |
| 424.53 | 2.77 | 2.77 |
| 371.48 | 3.16 | 3.16 |
| 410.43 | 4.48 | 4.48 |
| 476.41 | 4.20 | 4.20 |
| 483.95 | 6.96 | 6.96 |
| 524.96 | 6.03 | 6.03 |
| 319.41 | 3.39 | 3.39 |
| 430.49 | 4.43 | 4.43 |
| 323.74 | 2.25 | 2.25 |
| 393.36 | 1.91 | 1.91 |
| 541.99 | 6.97 | 6.97 |
| 423.52 | 3.16 | 3.16 |
| 369.43 | 4.51 | 4.51 |
| 375.48 | 3.48 | 3.48 |
| 354.32 | 0.95 | 0.95 |
| 386.88 | 3.13 | 3.13 |
| 316.74 | 3.83 | 3.83 |
| 351.45 | 3.93 | 3.93 |
| 438.96 | 3.11 | 3.11 |
| 345.83 | 1.92 | 1.92 |
| 260.34 | 4.79 | 4.79 |
| 359.86 | 2.69 | 2.69 |
| 496.51 | 3.06 | 3.06 |
| 398.53 | 4.33 | 4.33 |
| 254.72 | 3.59 | 3.59 |
| 427.37 | 1.73 | 1.73 |
| 427.51 | 4.00 | 4.00 |
| 331.42 | 1.60 | 1.60 |
| 499.58 | 4.79 | 4.79 |
| 471.53 | 4.71 | 4.71 |
| 457.50 | 4.02 | 4.02 |
| 457.50 | 3.97 | 3.97 |
| 429.45 | 3.59 | 3.59 |