Basic Information
ID: ALA3214907
Type: Functional
Description: PubChem BioAssay. Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214907
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.23 | 2.31 | 2.31 |
| 210.24 | 2.21 | 2.21 |
| 309.37 | 2.51 | 2.51 |
| 405.46 | 2.01 | 2.01 |
| 332.40 | 3.88 | 3.88 |
| 449.52 | 3.26 | 3.26 |
| 344.38 | 4.41 | 4.41 |
| 442.57 | 3.50 | 3.50 |
| 317.35 | 3.92 | 3.92 |
| 291.35 | 3.69 | 3.69 |
| 379.49 | 3.58 | 3.58 |
| 328.38 | 3.93 | 3.93 |
| 440.33 | 5.45 | 5.45 |
| 355.81 | 4.86 | 4.86 |
| 329.20 | 3.43 | 3.43 |
| 473.58 | 5.66 | 5.66 |
| 402.24 | 3.70 | 3.70 |
| 278.27 | 2.76 | 2.76 |
| 357.41 | 2.44 | 2.44 |
| 326.40 | 2.30 | 2.30 |
| 370.28 | 4.30 | 4.30 |
| 296.37 | 3.55 | 3.55 |
| 253.35 | 1.58 | 1.58 |
| 379.46 | 3.02 | 3.02 |
| 312.42 | 2.88 | 2.88 |
| 280.37 | 3.47 | 3.47 |
| 355.49 | 4.72 | 4.72 |
| 349.40 | 4.54 | 4.54 |
| 310.34 | 2.95 | 2.95 |
| 431.52 | 4.75 | 4.75 |
| 324.34 | 2.45 | 2.45 |
| 367.46 | 4.02 | 4.02 |
| 318.13 | 3.96 | 3.96 |
| 390.88 | 2.63 | 2.63 |
| 345.36 | 3.56 | 3.56 |
| 320.42 | 4.06 | 4.06 |
| 472.60 | 4.57 | 4.57 |
| 226.28 | 3.02 | 3.02 |
| 356.47 | 5.06 | 5.06 |
| 331.17 | 3.41 | 3.41 |
| 369.49 | 3.81 | 3.81 |
| 368.46 | 2.68 | 2.68 |
| 350.76 | 4.52 | 4.52 |
| 423.51 | 4.10 | 4.10 |
| 377.51 | 4.29 | 4.29 |
| 434.59 | 5.16 | 5.16 |
| 435.49 | 4.60 | 4.60 |
| 409.54 | 3.59 | 3.59 |
| 304.40 | 4.07 | 4.07 |
| 360.37 | 2.01 | 2.01 |
| 428.42 | 4.24 | 4.24 |
| 245.29 | 3.78 | 3.78 |
| 514.33 | 4.56 | 4.56 |
| 433.90 | 5.14 | 5.14 |
| 302.34 | 3.90 | 3.90 |
| 316.31 | 3.87 | 3.87 |
| 207.30 | 2.35 | 2.35 |
| 477.50 | 4.43 | 4.43 |
| 477.97 | 4.76 | 4.76 |
| 419.87 | 4.92 | 4.92 |
| 437.57 | 3.41 | 3.41 |
| 430.33 | 4.32 | 4.32 |
| 229.31 | 3.33 | 3.33 |
| 358.87 | 4.57 | 4.57 |
| 360.38 | 4.11 | 4.11 |
| 357.48 | 3.43 | 3.43 |
| 357.48 | 3.17 | 3.17 |
| 284.75 | 3.32 | 3.32 |
| 404.46 | 3.93 | 3.93 |
| 357.48 | 3.17 | 3.17 |
| 308.35 | 3.31 | 3.31 |
| 280.33 | 2.68 | 2.68 |
| 233.29 | 2.46 | 2.46 |
| 243.69 | 2.31 | 2.31 |
| 425.45 | 2.70 | 2.70 |
| 449.90 | 4.93 | 4.93 |
| 348.36 | 2.86 | 2.86 |
| 433.49 | 3.78 | 3.78 |
| 338.46 | 4.46 | 4.46 |
| 474.57 | 6.11 | 6.11 |
| 330.34 | 4.17 | 4.17 |
| 439.48 | 3.01 | 3.01 |
| 433.47 | 5.34 | 5.34 |
| 460.51 | 3.69 | 3.69 |
| 202.69 | 1.64 | 1.64 |
| 449.39 | 6.42 | 6.42 |
| 321.33 | 3.08 | 3.08 |
| 376.44 | 4.26 | 4.26 |
| 463.54 | 5.50 | 5.50 |
| 342.42 | 5.42 | 5.42 |
| 482.59 | 3.41 | 3.41 |
| 330.35 | 4.10 | 4.10 |
| 342.79 | 3.96 | 3.96 |
| 287.70 | 3.07 | 3.07 |
| 355.36 | 4.02 | 4.02 |
| 506.39 | 6.04 | 6.04 |
| 360.42 | 4.58 | 4.58 |
| 391.54 | 4.68 | 4.68 |
| 322.15 | 4.57 | 4.57 |
| 250.30 | 2.67 | 2.67 |
| 513.54 | 4.16 | 4.16 |
| 246.35 | 3.42 | 3.42 |
| 248.37 | 4.40 | 4.40 |
| 308.41 | 4.63 | 4.63 |
| 464.43 | 1.80 | 1.80 |
| 405.89 | 4.80 | 4.80 |
| 373.37 | 4.55 | 4.55 |
| 414.47 | 4.35 | 4.35 |
| 310.38 | 3.65 | 3.65 |
| 356.39 | 3.35 | 3.35 |
| 402.25 | 3.65 | 3.65 |
| 339.40 | 2.28 | 2.28 |
| 198.22 | 2.43 | 2.43 |
| 322.41 | 1.56 | 1.56 |
| 408.46 | 4.58 | 4.58 |
| 525.57 | 5.26 | 5.26 |
| 323.40 | 3.56 | 3.56 |
| 415.46 | 4.27 | 4.27 |
| 430.47 | 3.58 | 3.58 |
| 346.35 | 2.94 | 2.94 |
| 452.52 | 4.97 | 4.97 |
| 385.84 | 4.34 | 4.34 |
| 346.42 | 4.06 | 4.06 |
| 443.42 | 4.30 | 4.30 |
| 296.35 | 3.34 | 3.34 |
| 406.53 | 4.56 | 4.56 |
| 310.38 | 3.65 | 3.65 |
| 430.47 | 3.58 | 3.58 |
| 438.24 | 5.01 | 5.01 |
| 455.47 | 3.10 | 3.10 |
| 360.37 | 3.49 | 3.49 |
| 179.18 | 1.58 | 1.58 |
| 332.28 | 2.78 | 2.78 |