Basic Information
ID: ALA3214930
Type: Binding
Description: PubChem BioAssay. QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM10.. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214930
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.41 | -0.21 | -0.21 |
| 551.58 | 4.47 | 4.47 |
| 405.89 | 5.59 | 5.59 |
| 403.89 | 4.89 | 4.89 |
| 508.42 | 4.59 | 4.59 |
| 420.89 | 4.32 | 4.32 |
| 637.14 | 5.53 | 5.53 |
| 353.43 | 5.44 | 5.44 |
| 303.81 | 4.71 | 4.71 |
| 394.45 | 4.01 | 4.01 |
| 452.56 | 3.71 | 3.71 |
| 344.82 | 4.90 | 4.90 |
| 350.42 | 4.72 | 4.72 |
| 386.90 | 4.47 | 4.47 |
| 493.65 | 5.06 | 5.06 |
| 547.72 | 4.19 | 4.19 |
| 493.98 | 3.92 | 3.92 |
| 486.59 | 5.06 | 5.06 |
| 529.64 | 4.17 | 4.17 |
| 377.40 | 4.91 | 4.91 |
| 623.11 | 5.14 | 5.14 |
| 361.79 | 2.06 | 2.06 |
| 292.38 | 4.75 | 4.75 |
| 471.65 | 4.95 | 4.95 |
| 495.67 | 4.22 | 4.22 |
| 429.72 | 5.89 | 5.89 |
| 445.37 | 5.18 | 5.18 |
| 286.44 | 4.91 | 4.91 |
| 508.41 | 5.19 | 5.19 |
| 380.50 | 4.41 | 4.41 |
| 455.53 | 4.62 | 4.62 |
| 504.56 | 4.60 | 4.60 |
| 366.24 | 4.61 | 4.61 |
| 495.55 | 5.42 | 5.42 |
| 462.62 | 4.21 | 4.21 |
| 324.38 | 4.00 | 4.00 |
| 402.45 | 5.05 | 5.05 |
| 388.50 | 4.92 | 4.92 |
| 349.88 | 5.17 | 5.17 |
| 499.59 | 5.03 | 5.03 |
| 523.38 | 4.73 | 4.73 |
| 345.44 | 4.85 | 4.85 |
| 319.45 | 3.41 | 3.41 |
| 500.47 | 5.50 | 5.50 |
| 368.44 | 5.54 | 5.54 |
| 395.71 | 5.46 | 5.46 |
| 383.84 | 4.42 | 4.42 |
| 352.35 | 1.94 | 1.94 |
| 336.39 | 4.41 | 4.41 |
| 437.54 | 4.48 | 4.48 |
| 543.00 | 4.70 | 4.70 |
| 455.35 | 5.34 | 5.34 |
| 430.90 | 5.90 | 5.90 |
| 563.49 | 4.88 | 4.88 |
| 353.45 | 5.20 | 5.20 |
| 495.50 | 3.55 | 3.55 |
| 538.69 | 6.64 | 6.64 |
| 348.43 | 4.45 | 4.45 |
| 447.57 | 4.31 | 4.31 |
| 504.97 | 5.06 | 5.06 |
| 607.11 | 5.76 | 5.76 |
| 366.42 | 4.85 | 4.85 |
| 438.51 | 3.72 | 3.72 |
| 467.21 | 5.25 | 5.25 |
| 470.59 | 6.33 | 6.33 |
| 533.27 | 5.87 | 5.87 |
| 450.94 | 3.70 | 3.70 |
| 449.54 | 6.65 | 6.65 |
| 425.36 | 5.93 | 5.93 |
| 568.93 | 6.24 | 6.24 |
| 467.35 | 4.91 | 4.91 |
| 468.62 | 4.57 | 4.57 |
| 396.86 | 0.92 | 0.92 |
| 534.62 | 5.29 | 5.29 |
| 449.53 | 5.55 | 5.55 |
| 369.48 | 4.13 | 4.13 |
| 470.52 | 3.76 | 3.76 |
| 456.87 | 5.96 | 5.96 |
| 461.01 | 5.64 | 5.64 |
| 448.27 | 4.70 | 4.70 |
| 464.53 | 5.13 | 5.13 |
| 287.53 | 2.72 | 2.72 |
| 344.46 | 3.91 | 3.91 |
| 519.98 | 4.56 | 4.56 |
| 360.42 | 4.26 | 4.26 |
| 569.80 | 5.37 | 5.37 |
| 385.47 | 5.16 | 5.16 |
| 203.14 | 1.41 | 1.41 |
| 460.49 | 5.22 | 5.22 |
| 451.48 | 4.68 | 4.68 |
| 459.33 | 5.88 | 5.88 |
| 416.87 | 5.02 | 5.02 |
| 481.57 | 3.94 | 3.94 |
| 352.39 | 4.54 | 4.54 |
| 514.20 | 4.95 | 4.95 |
| 406.53 | 5.59 | 5.59 |
| 476.53 | 5.55 | 5.55 |
| 524.62 | 4.82 | 4.82 |
| 447.61 | 6.02 | 6.02 |
| 360.37 | 3.65 | 3.65 |
| 553.34 | 4.85 | 4.85 |
| 431.90 | 4.79 | 4.79 |
| 436.47 | 4.16 | 4.16 |
| 342.42 | 4.92 | 4.92 |
| 567.33 | 6.87 | 6.87 |
| 529.64 | 4.11 | 4.11 |
| 482.59 | 3.63 | 3.63 |
| 471.99 | 5.79 | 5.79 |
| 304.35 | 4.42 | 4.42 |
| 374.32 | 5.22 | 5.22 |
| 372.42 | 5.04 | 5.04 |
| 507.02 | 6.55 | 6.55 |
| 369.79 | 4.10 | 4.10 |
| 461.54 | 5.41 | 5.41 |
| 536.61 | 2.93 | 2.93 |
| 240.28 | 0.42 | 0.42 |
| 339.51 | 5.44 | 5.44 |
| 577.68 | 4.05 | 4.05 |
| 474.94 | 5.68 | 5.68 |
| 458.43 | 4.50 | 4.50 |
| 473.48 | 5.11 | 5.11 |
| 499.64 | 5.42 | 5.42 |
| 459.93 | 5.23 | 5.23 |
| 615.22 | 4.96 | 4.96 |
| 421.35 | 5.13 | 5.13 |
| 432.43 | 5.48 | 5.48 |
| 358.85 | 4.77 | 4.77 |
| 386.50 | 4.90 | 4.90 |
| 424.50 | 4.70 | 4.70 |
| 368.38 | 4.24 | 4.24 |
| 517.61 | 4.74 | 4.74 |
| 460.41 | 5.52 | 5.52 |
| 446.98 | 5.33 | 5.33 |
| 437.50 | 5.19 | 5.19 |
| 605.74 | 5.06 | 5.06 |
| 352.39 | 4.54 | 4.54 |
| 623.63 | 6.32 | 6.32 |
| 392.91 | 5.67 | 5.67 |
| 497.62 | 4.67 | 4.67 |
| 676.82 | 7.02 | 7.02 |
| 392.25 | 4.07 | 4.07 |
| 447.56 | 4.81 | 4.81 |
| 437.42 | 6.10 | 6.10 |
| 349.62 | 4.87 | 4.87 |
| 417.39 | 4.78 | 4.78 |
| 389.41 | 4.49 | 4.49 |
| 614.76 | 5.95 | 5.95 |
| 667.82 | 6.31 | 6.31 |
| 539.70 | 3.14 | 3.14 |
| 465.35 | 4.84 | 4.84 |
| 626.73 | 6.61 | 6.61 |
| 667.82 | 6.31 | 6.31 |
| 667.82 | 6.31 | 6.31 |
| 653.80 | 5.92 | 5.92 |
| 667.82 | 6.31 | 6.31 |
| 614.76 | 5.95 | 5.95 |
| 506.71 | 4.06 | 4.06 |
| 868.99 | 5.74 | 5.74 |
| 667.82 | 6.00 | 6.00 |
| 667.82 | 6.31 | 6.31 |
| 297.27 | 2.56 | 2.56 |
| 714.06 | 6.53 | 6.53 |
| 369.80 | 5.26 | 5.26 |
| 549.74 | 4.72 | 4.72 |
| 720.02 | 6.03 | 6.03 |
| 365.43 | 5.19 | 5.19 |
| 537.46 | 5.96 | 5.96 |
| 461.52 | 4.89 | 4.89 |
| 385.36 | 5.36 | 5.36 |
| 593.57 | 4.81 | 4.81 |
| 357.38 | 5.09 | 5.09 |
| 593.75 | 2.37 | 2.37 |
| 321.40 | 4.81 | 4.81 |
| 768.95 | 7.18 | 7.18 |
| 471.61 | 3.67 | 3.67 |
| 465.51 | 4.72 | 4.72 |
| 730.06 | 6.23 | 6.23 |
| 390.41 | 2.27 | 2.27 |
| 403.35 | 5.63 | 5.63 |
| 610.18 | 5.18 | 5.18 |
| 388.44 | 5.18 | 5.18 |
| 529.65 | 4.39 | 4.39 |
| 539.51 | 4.14 | 4.14 |
| 406.41 | 5.70 | 5.70 |
| 507.43 | 5.95 | 5.95 |
| 439.36 | 6.44 | 6.44 |
| 493.61 | 5.64 | 5.64 |
| 325.41 | 4.71 | 4.71 |
| 467.42 | 5.06 | 5.06 |
| 433.45 | 5.77 | 5.77 |
| 407.34 | 5.70 | 5.70 |
| 752.83 | 6.60 | 6.60 |
| 712.04 | 6.37 | 6.37 |
| 379.36 | 4.34 | 4.34 |
| 258.24 | 2.14 | 2.14 |
| 480.59 | 4.46 | 4.46 |
| 456.45 | 4.86 | 4.86 |
| 879.00 | 4.20 | 4.20 |
| 502.68 | 4.19 | 4.19 |
| 764.86 | 6.47 | 6.47 |
| 502.68 | 4.19 | 4.19 |
| 542.69 | 6.24 | 6.24 |
| 559.54 | 3.08 | 3.08 |
| 472.61 | 5.27 | 5.27 |
| 560.74 | 5.62 | 5.62 |
| 648.84 | 6.62 | 6.62 |
| 547.11 | 6.88 | 6.88 |
| 526.69 | 6.54 | 6.54 |
| 639.23 | 6.87 | 6.87 |
| 488.59 | 6.17 | 6.17 |
| 622.70 | 6.22 | 6.22 |
| 516.52 | 5.97 | 5.97 |
| 612.81 | 5.80 | 5.80 |
| 533.70 | 7.02 | 7.02 |
| 581.67 | 6.68 | 6.68 |
| 757.81 | 7.04 | 7.04 |
| 424.61 | 4.96 | 4.96 |
| 488.95 | 3.95 | 3.95 |
| 325.59 | 4.36 | 4.36 |
| 382.49 | 3.16 | 3.16 |
| 302.38 | 4.43 | 4.43 |
| 390.44 | 4.05 | 4.05 |
| 342.24 | 4.77 | 4.77 |
| 492.52 | 5.40 | 5.40 |
| 389.48 | 4.00 | 4.00 |
| 466.38 | 5.29 | 5.29 |
| 315.44 | 2.22 | 2.22 |
| 480.59 | 5.70 | 5.70 |
| 279.37 | 4.41 | 4.41 |
| 406.90 | 5.02 | 5.02 |
| 475.51 | 4.11 | 4.11 |
| 482.38 | 4.99 | 4.99 |
| 436.54 | 4.14 | 4.14 |
| 370.63 | 4.50 | 4.50 |
| 495.40 | 5.00 | 5.00 |