Basic Information
ID: ALA3214946
Type: Functional
Description: PubChem BioAssay. qHTS for Inhibitors of WRN Helicase: Confirmatory Assay for Cherry-picked Compounds.. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214946
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.53 | 0.00 | 0.00 |
| 444.49 | -0.14 | -0.14 |
| 344.44 | 2.59 | 2.59 |
| 286.24 | 2.28 | 2.28 |
| 223.23 | 2.31 | 2.31 |
| 197.19 | 0.05 | 0.05 |
| 328.44 | 3.40 | 3.40 |
| 401.87 | 2.73 | 2.73 |
| 368.48 | 4.88 | 4.88 |
| 327.37 | 2.86 | 2.86 |
| 1101.28 | ||
| 640.59 | 1.37 | 1.37 |
| 729.78 | 1.42 | 1.42 |
| 259.74 | 1.98 | 1.98 |
| 400.36 | 2.93 | 2.93 |
| 294.29 | 1.83 | 1.83 |
| 349.39 | 1.73 | 1.73 |
| 389.80 | 5.24 | 5.24 |
| 355.35 | 4.59 | 4.59 |
| 345.38 | 3.54 | 3.54 |
| 306.28 | 3.85 | 3.85 |
| 297.36 | 2.35 | 2.35 |
| 358.38 | 2.06 | 2.06 |
| 309.37 | 2.51 | 2.51 |
| 349.96 | 3.04 | 3.04 |
| 563.99 | 1.03 | 1.03 |
| 434.54 | 4.11 | 4.11 |
| 304.25 | 1.19 | 1.19 |
| 412.44 | 3.96 | 3.96 |
| 330.29 | 1.53 | 1.53 |
| 462.98 | 5.25 | 5.25 |
| 282.30 | 3.10 | 3.10 |
| 302.23 | 0.07 | 0.07 |
| 221.20 | 0.47 | 0.47 |
| 222.27 | 2.23 | 2.23 |
| 458.63 | 4.56 | 4.56 |
| 281.27 | 1.87 | 1.87 |
| 290.75 | 1.76 | 1.76 |
| 320.25 | 1.99 | 1.99 |
| 329.36 | 4.73 | 4.73 |
| 214.26 | 1.09 | 1.09 |
| 416.31 | 3.90 | 3.90 |
| 310.31 | 2.40 | 2.40 |
| 529.69 | 4.69 | 4.69 |
| 453.52 | 4.59 | 4.59 |
| 365.48 | 3.17 | 3.17 |
| 299.29 | 1.28 | 1.28 |
| 386.51 | 3.27 | 3.27 |
| 425.54 | 3.27 | 3.27 |
| 405.53 | 4.02 | 4.02 |
| 407.29 | 3.16 | 3.16 |
| 340.31 | 2.64 | 2.64 |
| 306.67 | 3.23 | 3.23 |
| 277.28 | 3.04 | 3.04 |
| 527.61 | 5.57 | 5.57 |
| 447.55 | 4.45 | 4.45 |
| 395.46 | 3.52 | 3.52 |
| 391.42 | 4.45 | 4.45 |
| 563.99 | 1.03 | 1.03 |
| 284.27 | 2.88 | 2.88 |
| 372.43 | 3.09 | 3.09 |
| 415.45 | 2.37 | 2.37 |
| 366.23 | 4.55 | 4.55 |
| 406.53 | 2.39 | 2.39 |
| 364.43 | 4.47 | 4.47 |
| 429.46 | 4.28 | 4.28 |
| 260.25 | 1.47 | 1.47 |
| 397.46 | 3.53 | 3.53 |
| 459.62 | 5.16 | 5.16 |
| 403.45 | 3.69 | 3.69 |
| 298.32 | 2.11 | 2.11 |
| 477.01 | 4.98 | 4.98 |
| 332.15 | 4.26 | 4.26 |
| 490.54 | 5.25 | 5.25 |
| 379.85 | 3.28 | 3.28 |
| 209.27 | 1.28 | 1.28 |
| 500.51 | 3.87 | 3.87 |
| 398.47 | 3.62 | 3.62 |
| 268.35 | 2.68 | 2.68 |
| 350.33 | 3.56 | 3.56 |
| 343.32 | 2.32 | 2.32 |
| 286.29 | 2.20 | 2.20 |
| 271.24 | 0.12 | 0.12 |
| 389.91 | 2.47 | 2.47 |
| 396.40 | 2.37 | 2.37 |
| 340.40 | 5.43 | 5.43 |
| 385.49 | 3.77 | 3.77 |
| 372.56 | 4.84 | 4.84 |
| 389.21 | 2.62 | 2.62 |
| 444.45 | 3.02 | 3.02 |
| 354.39 | 4.11 | 4.11 |
| 454.51 | 3.51 | 3.51 |
| 476.38 | 4.79 | 4.79 |
| 496.57 | 3.91 | 3.91 |
| 319.32 | 3.67 | 3.67 |
| 552.34 | 3.92 | 3.92 |
| 314.37 | 0.62 | 0.62 |
| 338.39 | 3.65 | 3.65 |
| 415.84 | 6.06 | 6.06 |
| 500.51 | 3.66 | 3.66 |
| 368.42 | 2.75 | 2.75 |
| 427.33 | 4.45 | 4.45 |
| 209.20 | 0.11 | 0.11 |
| 361.36 | 4.50 | 4.50 |
| 245.28 | 2.61 | 2.61 |
| 416.43 | 3.98 | 3.98 |
| 356.41 | 3.49 | 3.49 |
| 477.90 | 4.11 | 4.11 |
| 450.56 | 4.56 | 4.56 |
| 467.95 | 4.53 | 4.53 |
| 275.37 | 3.73 | 3.73 |
| 449.54 | 3.83 | 3.83 |
| 472.55 | 2.09 | 2.09 |
| 366.42 | 3.50 | 3.50 |
| 322.28 | 2.74 | 2.74 |
| 299.71 | 3.39 | 3.39 |
| 401.27 | 3.29 | 3.29 |
| 466.54 | 3.90 | 3.90 |
| 338.79 | 2.06 | 2.06 |
| 322.32 | 3.34 | 3.34 |
| 368.46 | 6.07 | 6.07 |
| 470.53 | 4.45 | 4.45 |
| 476.55 | 5.02 | 5.02 |
| 343.27 | 3.22 | 3.22 |
| 240.26 | 2.56 | 2.56 |
| 338.39 | 3.98 | 3.98 |
| 462.48 | 4.23 | 4.23 |
| 396.41 | -1.07 | -1.07 |
| 418.41 | 3.28 | 3.28 |
| 458.45 | 3.57 | 3.57 |
| 395.51 | 3.87 | 3.87 |
| 304.37 | 2.21 | 2.21 |
| 429.50 | 4.68 | 4.68 |
| 404.30 | 3.79 | 3.79 |
| 318.36 | 1.75 | 1.75 |
| 374.35 | 4.51 | 4.51 |
| 349.39 | 3.69 | 3.69 |
| 315.37 | 5.11 | 5.11 |
| 499.55 | 5.28 | 5.28 |
| 387.44 | 4.67 | 4.67 |
| 410.74 | 4.54 | 4.54 |
| 529.16 | 5.53 | 5.53 |
| 422.82 | 4.07 | 4.07 |
| 452.29 | 1.91 | 1.91 |
| 319.32 | 3.69 | 3.69 |
| 448.53 | 2.57 | 2.57 |
| 208.17 | 0.25 | 0.25 |
| 483.55 | 4.60 | 4.60 |
| 502.47 | 6.00 | 6.00 |
| 414.48 | 3.11 | 3.11 |
| 384.28 | 3.25 | 3.25 |
| 404.49 | 4.67 | 4.67 |
| 356.37 | -0.72 | -0.72 |
| 354.36 | 3.21 | 3.21 |
| 425.47 | 2.83 | 2.83 |
| 354.41 | 5.42 | 5.42 |
| 444.49 | 1.31 | 1.31 |
| 326.31 | 1.95 | 1.95 |
| 308.36 | 3.82 | 3.82 |
| 464.57 | 4.86 | 4.86 |
| 397.34 | 1.80 | 1.80 |
| 370.79 | 3.57 | 3.57 |
| 498.56 | 1.55 | 1.55 |
| 334.68 | 3.23 | 3.23 |
| 315.42 | 3.37 | 3.37 |
| 392.48 | 2.93 | 2.93 |
| 461.87 | 4.70 | 4.70 |
| 322.35 | 3.60 | 3.60 |
| 402.45 | 3.71 | 3.71 |
| 350.40 | 4.16 | 4.16 |
| 380.40 | 2.51 | 2.51 |
| 287.36 | 2.97 | 2.97 |
| 345.40 | 4.03 | 4.03 |
| 391.47 | 3.25 | 3.25 |
| 404.17 | 3.53 | 3.53 |
| 416.42 | 1.27 | 1.27 |
| 304.37 | 2.26 | 2.26 |
| 377.37 | 1.81 | 1.81 |
| 512.97 | 2.92 | 2.92 |
| 407.81 | 3.93 | 3.93 |
| 389.37 | 4.82 | 4.82 |
| 278.31 | 3.39 | 3.39 |
| 435.50 | 3.26 | 3.26 |
| 391.38 | -2.27 | -2.27 |
| 348.36 | 1.22 | 1.22 |
| 416.48 | 3.60 | 3.60 |
| 262.27 | 2.65 | 2.65 |
| 254.35 | 3.53 | 3.53 |
| 386.79 | 2.65 | 2.65 |
| 461.57 | 3.01 | 3.01 |
| 443.24 | 4.41 | 4.41 |
| 347.42 | 3.50 | 3.50 |
| 487.65 | 4.86 | 4.86 |
| 390.49 | 1.81 | 1.81 |
| 356.41 | 1.25 | 1.25 |
| 378.43 | 3.91 | 3.91 |
| 476.41 | 4.20 | 4.20 |
| 328.73 | 2.48 | 2.48 |
| 469.45 | 2.20 | 2.20 |
| 369.48 | 4.01 | 4.01 |
| 353.40 | 4.67 | 4.67 |
| 506.41 | 4.80 | 4.80 |
| 372.56 | 4.84 | 4.84 |
| 408.40 | 1.79 | 1.79 |
| 415.42 | 3.63 | 3.63 |
| 324.33 | 2.98 | 2.98 |
| 383.40 | 3.86 | 3.86 |
| 395.42 | 5.08 | 5.08 |
| 478.45 | -1.24 | -1.24 |
| 443.24 | 5.05 | 5.05 |
| 466.47 | 4.48 | 4.48 |
| 259.33 | 3.28 | 3.28 |
| 363.37 | 3.41 | 3.41 |
| 343.77 | 2.34 | 2.34 |
| 392.44 | 3.90 | 3.90 |
| 349.30 | -0.46 | -0.46 |
| 376.29 | 4.33 | 4.33 |
| 432.46 | 4.47 | 4.47 |
| 400.49 | 4.07 | 4.07 |
| 371.44 | 4.97 | 4.97 |
| 390.26 | 4.23 | 4.23 |
| 255.27 | 2.23 | 2.23 |
| 324.41 | 4.54 | 4.54 |
| 340.29 | 2.90 | 2.90 |
| 198.22 | 1.23 | 1.23 |
| 288.69 | 3.48 | 3.48 |
| 382.89 | 2.95 | 2.95 |
| 258.23 | 2.42 | 2.42 |
| 262.26 | 2.92 | 2.92 |
| 376.25 | 4.07 | 4.07 |
| 317.73 | 3.06 | 3.06 |
| 309.33 | 1.69 | 1.69 |
| 306.46 | 3.58 | 3.58 |
| 374.49 | 3.13 | 3.13 |
| 359.41 | 4.42 | 4.42 |
| 322.75 | 3.09 | 3.09 |
| 406.87 | 4.36 | 4.36 |
| 538.54 | 2.93 | 2.93 |
| 307.29 | 1.85 | 1.85 |
| 427.24 | 5.50 | 5.50 |
| 297.37 | 0.24 | 0.24 |
| 301.39 | 3.36 | 3.36 |
| 364.32 | 4.79 | 4.79 |
| 488.59 | 4.77 | 4.77 |
| 362.34 | 2.61 | 2.61 |
| 429.47 | 4.79 | 4.79 |
| 332.38 | 2.91 | 2.91 |
| 381.46 | 3.83 | 3.83 |
| 331.33 | 3.19 | 3.19 |
| 402.45 | 2.65 | 2.65 |
| 478.67 | 3.37 | 3.37 |
| 330.48 | 2.22 | 2.22 |
| 329.40 | 3.95 | 3.95 |
| 322.41 | 4.80 | 4.80 |
| 387.87 | 5.11 | 5.11 |
| 475.29 | 4.42 | 4.42 |
| 372.47 | 3.65 | 3.65 |
| 349.21 | 3.69 | 3.69 |
| 367.41 | 2.79 | 2.79 |
| 505.87 | 5.49 | 5.49 |
| 371.28 | 5.47 | 5.47 |
| 418.45 | 3.23 | 3.23 |
| 376.32 | 4.21 | 4.21 |
| 322.15 | 4.57 | 4.57 |
| 336.41 | 2.32 | 2.32 |
| 480.47 | 1.57 | 1.57 |
| 426.29 | 3.04 | 3.04 |
| 320.31 | 1.91 | 1.91 |
| 494.41 | 6.67 | 6.67 |
| 316.34 | 2.50 | 2.50 |
| 352.44 | 2.56 | 2.56 |
| 299.24 | 2.78 | 2.78 |
| 288.25 | 2.22 | 2.22 |
| 212.63 | 2.98 | 2.98 |
| 435.53 | 3.50 | 3.50 |
| 353.38 | 1.96 | 1.96 |
| 516.47 | 6.12 | 6.12 |
| 466.83 | 3.55 | 3.55 |
| 373.35 | 2.33 | 2.33 |
| 373.21 | 2.32 | 2.32 |
| 361.45 | 3.80 | 3.80 |
| 458.43 | 3.68 | 3.68 |
| 497.50 | 1.02 | 1.02 |
| 486.46 | 3.25 | 3.25 |
| 395.48 | 2.62 | 2.62 |
| 444.40 | 2.54 | 2.54 |
| 379.44 | 4.91 | 4.91 |
| 403.37 | 2.34 | 2.34 |
| 485.02 | 6.34 | 6.34 |
| 388.22 | 3.90 | 3.90 |
| 459.53 | 6.38 | 6.38 |
| 341.38 | 3.33 | 3.33 |
| 329.38 | 2.51 | 2.51 |
| 372.28 | 2.86 | 2.86 |
| 491.36 | 4.57 | 4.57 |
| 458.59 | 4.59 | 4.59 |
| 418.45 | 2.91 | 2.91 |
| 320.36 | 2.53 | 2.53 |
| 396.31 | 3.24 | 3.24 |
| 340.34 | 3.22 | 3.22 |
| 408.80 | 3.76 | 3.76 |
| 444.13 | 5.32 | 5.32 |
| 366.38 | 5.38 | 5.38 |
| 331.71 | 3.61 | 3.61 |
| 451.82 | 5.01 | 5.01 |
| 432.72 | 3.91 | 3.91 |
| 314.18 | 2.66 | 2.66 |
| 428.50 | 3.62 | 3.62 |
| 440.33 | 5.11 | 5.11 |
| 350.33 | 4.29 | 4.29 |
| 383.50 | 4.26 | 4.26 |
| 314.33 | 2.31 | 2.31 |
| 373.35 | 2.33 | 2.33 |
| 367.88 | 1.10 | 1.10 |
| 460.51 | 3.69 | 3.69 |
| 394.54 | 4.76 | 4.76 |
| 416.48 | 3.60 | 3.60 |
| 337.38 | 3.98 | 3.98 |
| 320.32 | 4.83 | 4.83 |
| 262.29 | 1.09 | 1.09 |
| 375.34 | 2.46 | 2.46 |
| 391.90 | 4.46 | 4.46 |
| 582.06 | 4.43 | 4.43 |
| 322.32 | 1.90 | 1.90 |
| 278.31 | 3.28 | 3.28 |
| 326.31 | 1.95 | 1.95 |
| 337.29 | 2.46 | 2.46 |
| 405.50 | 3.01 | 3.01 |
| 331.22 | 1.77 | 1.77 |
| 491.43 | 3.30 | 3.30 |
| 312.35 | 3.62 | 3.62 |
| 405.82 | 3.94 | 3.94 |
| 531.78 | 5.39 | 5.39 |
| 418.45 | 2.91 | 2.91 |
| 373.37 | 3.27 | 3.27 |
| 355.44 | 4.83 | 4.83 |
| 514.61 | 4.01 | 4.01 |
| 365.30 | 3.59 | 3.59 |
| 423.90 | 4.18 | 4.18 |
| 459.51 | 2.41 | 2.41 |
| 287.70 | 3.92 | 3.92 |
| 361.42 | 3.05 | 3.05 |
| 300.34 | 0.91 | 0.91 |
| 326.36 | 2.98 | 2.98 |
| 430.46 | 2.40 | 2.40 |
| 349.39 | 3.69 | 3.69 |
| 451.53 | 4.61 | 4.61 |
| 365.37 | 4.05 | 4.05 |
| 504.56 | 5.30 | 5.30 |
| 507.68 | ||
| 323.40 | 2.90 | 2.90 |
| 385.27 | 3.62 | 3.62 |
| 381.46 | 3.83 | 3.83 |
| 327.41 | 2.67 | 2.67 |
| 279.32 | 1.49 | 1.49 |
| 314.27 | 2.08 | 2.08 |
| 280.30 | 2.26 | 2.26 |
| 323.33 | 3.97 | 3.97 |
| 253.28 | 3.19 | 3.19 |
| 434.52 | 4.10 | 4.10 |
| 432.48 | 3.30 | 3.30 |
| 368.40 | 2.24 | 2.24 |
| 328.35 | 2.12 | 2.12 |
| 388.38 | 3.03 | 3.03 |
| 393.19 | 2.34 | 2.34 |
| 433.52 | 4.04 | 4.04 |
| 397.46 | 3.53 | 3.53 |
| 497.58 | 5.89 | 5.89 |
| 395.41 | 4.01 | 4.01 |
| 277.37 | 3.73 | 3.73 |
| 312.28 | 2.09 | 2.09 |
| 314.32 | 3.06 | 3.06 |
| 402.36 | 3.89 | 3.89 |
| 494.98 | 4.21 | 4.21 |
| 264.28 | 3.47 | 3.47 |
| 422.82 | 3.82 | 3.82 |
| 432.48 | 2.66 | 2.66 |
| 268.22 | 2.44 | 2.44 |
| 391.25 | 4.61 | 4.61 |
| 288.35 | 3.08 | 3.08 |
| 481.00 | 3.99 | 3.99 |
| 234.28 | 2.07 | 2.07 |
| 340.39 | 3.94 | 3.94 |
| 513.54 | 4.16 | 4.16 |
| 333.32 | 2.25 | 2.25 |
| 411.41 | 2.47 | 2.47 |
| 571.58 | 0.60 | 0.60 |
| 542.54 | 1.29 | 1.29 |
| 477.74 | 0.71 | 0.71 |
| 506.97 | 5.43 | 5.43 |
| 315.35 | 2.67 | 2.67 |
| 418.45 | 5.87 | 5.87 |
| 429.31 | 2.81 | 2.81 |
| 455.51 | 5.22 | 5.22 |
| 232.19 | 2.01 | 2.01 |
| 440.54 | 1.23 | 1.23 |
| 528.51 | 1.06 | 1.06 |
| 450.62 | 6.70 | 6.70 |
| 488.47 | 0.32 | 0.32 |
| 412.49 | 0.45 | 0.45 |
| 555.58 | 1.63 | 1.63 |
| 498.39 | 5.98 | 5.98 |
| 514.56 | 1.23 | 1.23 |
| 385.49 | 3.86 | 3.86 |
| 296.20 | 1.98 | 1.98 |
| 714.56 | 3.55 | 3.55 |
| 414.81 | 1.81 | 1.81 |
| 414.37 | 4.53 | 4.53 |
| 311.77 | 3.35 | 3.35 |
| 304.36 | 2.38 | 2.38 |
| 322.27 | 2.28 | 2.28 |
| 678.15 | 6.44 | 6.44 |
| 230.18 | 1.32 | 1.32 |
| 315.35 | 3.54 | 3.54 |
| 412.97 | 4.97 | 4.97 |
| 390.87 | 2.09 | 2.09 |
| 342.81 | 3.33 | 3.33 |
| 240.26 | 3.70 | 3.70 |
| 294.38 | 4.27 | 4.27 |
| 400.91 | 3.29 | 3.29 |
| 264.09 | 2.40 | 2.40 |
| 546.16 | 7.01 | 7.01 |
| 319.40 | 3.97 | 3.97 |
| 416.31 | 3.90 | 3.90 |
| 371.40 | 3.86 | 3.86 |
| 452.10 | 4.09 | 4.09 |
| 449.47 | 3.52 | 3.52 |
| 267.37 | 3.14 | 3.14 |
| 483.57 | 4.12 | 4.12 |
| 455.49 | 2.97 | 2.97 |
| 205.17 | 2.16 | 2.16 |
| 417.85 | 4.02 | 4.02 |
| 426.48 | 4.14 | 4.14 |
| 404.43 | 3.66 | 3.66 |
| 395.53 | 3.52 | 3.52 |
| 453.55 | 4.19 | 4.19 |
| 460.49 | 4.22 | 4.22 |
| 467.57 | 4.58 | 4.58 |
| 425.48 | 2.06 | 2.06 |
| 274.37 | 4.47 | 4.47 |
| 470.53 | 4.54 | 4.54 |
| 458.54 | 3.71 | 3.71 |
| 362.39 | 2.65 | 2.65 |
| 396.83 | 5.31 | 5.31 |
| 612.15 | 5.86 | 5.86 |
| 272.26 | 1.96 | 1.96 |
| 577.44 | 3.58 | 3.58 |
| 334.76 | 3.82 | 3.82 |
| 305.38 | 4.31 | 4.31 |
| 390.40 | 3.39 | 3.39 |
| 397.46 | 3.21 | 3.21 |
| 543.00 | 2.92 | 2.92 |
| 404.25 | 2.73 | 2.73 |
| 410.81 | 3.73 | 3.73 |
| 464.43 | 1.80 | 1.80 |
| 406.39 | 3.09 | 3.09 |
| 403.41 | 4.00 | 4.00 |
| 333.26 | 0.78 | 0.78 |
| 343.36 | 2.48 | 2.48 |
| 415.45 | 4.46 | 4.46 |
| 372.38 | 3.35 | 3.35 |
| 414.87 | 3.30 | 3.30 |
| 388.40 | 3.42 | 3.42 |
| 397.46 | 3.21 | 3.21 |
| 472.44 | 2.95 | 2.95 |
| 518.59 | 5.22 | 5.22 |
| 230.22 | 1.98 | 1.98 |
| 331.75 | 4.30 | 4.30 |
| 471.43 | 2.78 | 2.78 |
| 330.30 | 1.18 | 1.18 |
| 286.36 | 3.55 | 3.55 |
| 450.45 | 3.89 | 3.89 |
| 301.26 | 3.00 | 3.00 |
| 416.46 | 4.03 | 4.03 |
| 452.26 | 4.45 | 4.45 |
| 360.38 | 2.73 | 2.73 |
| 384.23 | 1.75 | 1.75 |
| 879.86 | 6.39 | 6.39 |
| 282.37 | 3.46 | 3.46 |
| 577.71 | 5.21 | 5.21 |
| 472.44 | 2.36 | 2.36 |
| 472.44 | 2.36 | 2.36 |
| 438.89 | 5.07 | 5.07 |
| 435.90 | 5.33 | 5.33 |
| 488.89 | 2.87 | 2.87 |
| 438.89 | 5.07 | 5.07 |
| 378.46 | 2.46 | 2.46 |
| 266.60 | 1.41 | 1.41 |
| 388.38 | 5.44 | 5.44 |
| 434.41 | 3.08 | 3.08 |
| 373.32 | 1.82 | 1.82 |
| 459.89 | 4.78 | 4.78 |
| 371.38 | 1.77 | 1.77 |
| 403.46 | 2.32 | 2.32 |
| 383.36 | 0.12 | 0.12 |
| 497.56 | 4.59 | 4.59 |
| 486.12 | 3.46 | 3.46 |
| 474.53 | 3.89 | 3.89 |
| 474.54 | 4.68 | 4.68 |
| 381.44 | 4.67 | 4.67 |
| 435.44 | 3.95 | 3.95 |
| 334.34 | 2.62 | 2.62 |