Basic Information
ID: ALA3214955
Type: Functional
Description: PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12). (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3214955
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 240.33 | 3.85 | 3.85 |
| 235.29 | 3.92 | 3.92 |
| 258.32 | 3.99 | 3.99 |
| 339.35 | 2.44 | 2.44 |
| 287.32 | 3.10 | 3.10 |
| 264.28 | 2.99 | 2.99 |
| 227.29 | 3.67 | 3.67 |
| 212.25 | 2.93 | 2.93 |
| 270.26 | 3.55 | 3.55 |
| 321.21 | 3.92 | 3.92 |
| 263.30 | 3.82 | 3.82 |
| 314.30 | 2.83 | 2.83 |
| 263.13 | 4.31 | 4.31 |
| 279.34 | 3.59 | 3.59 |
| 254.31 | 5.02 | 5.02 |
| 238.29 | 3.64 | 3.64 |
| 296.28 | 2.60 | 2.60 |
| 316.20 | 4.57 | 4.57 |
| 308.35 | 1.20 | 1.20 |
| 248.28 | 2.08 | 2.08 |
| 321.13 | 3.77 | 3.77 |
| 244.69 | 2.66 | 2.66 |
| 252.32 | 2.87 | 2.87 |
| 359.86 | 5.67 | 5.67 |
| 237.26 | 3.71 | 3.71 |
| 320.39 | 3.22 | 3.22 |
| 436.50 | 2.91 | 2.91 |
| 258.30 | 3.47 | 3.47 |
| 251.29 | 4.60 | 4.60 |
| 397.48 | 3.68 | 3.68 |
| 300.27 | 1.78 | 1.78 |
| 281.38 | 4.57 | 4.57 |
| 251.26 | 3.11 | 3.11 |
| 291.31 | 3.87 | 3.87 |
| 264.28 | 2.29 | 2.29 |
| 298.37 | 3.51 | 3.51 |
| 307.35 | 4.11 | 4.11 |
| 319.43 | 2.58 | 2.58 |
| 255.34 | 3.35 | 3.35 |
| 295.34 | 4.26 | 4.26 |
| 377.47 | 2.84 | 2.84 |
| 253.31 | 3.05 | 3.05 |
| 383.52 | 3.92 | 3.92 |
| 256.22 | 3.11 | 3.11 |
| 282.37 | 4.56 | 4.56 |
| 266.30 | 3.46 | 3.46 |
| 333.19 | 3.08 | 3.08 |
| 524.46 | 3.30 | 3.30 |
| 323.37 | 4.54 | 4.54 |
| 449.65 | 4.88 | 4.88 |
| 249.27 | 2.88 | 2.88 |
| 232.24 | 1.94 | 1.94 |
| 258.35 | 2.58 | 2.58 |
| 307.35 | 4.11 | 4.11 |
| 269.33 | 3.25 | 3.25 |
| 288.39 | 3.64 | 3.64 |
| 395.49 | 3.75 | 3.75 |
| 251.29 | 4.02 | 4.02 |
| 304.42 | 3.80 | 3.80 |
| 335.20 | 2.96 | 2.96 |
| 290.32 | 3.19 | 3.19 |
| 220.30 | 2.43 | 2.43 |
| 295.40 | 2.40 | 2.40 |
| 270.27 | 3.35 | 3.35 |
| 273.39 | 4.32 | 4.32 |
| 303.75 | 3.27 | 3.27 |
| 280.28 | 3.32 | 3.32 |
| 313.42 | 4.16 | 4.16 |
| 277.32 | 3.94 | 3.94 |
| 258.37 | 3.98 | 3.98 |
| 274.71 | 3.03 | 3.03 |
| 251.29 | 4.02 | 4.02 |
| 303.35 | 1.71 | 1.71 |
| 336.35 | 3.30 | 3.30 |
| 256.27 | 3.73 | 3.73 |
| 271.38 | 3.82 | 3.82 |
| 373.55 | 4.53 | 4.53 |
| 273.29 | 3.40 | 3.40 |
| 267.72 | 3.63 | 3.63 |
| 266.30 | 3.70 | 3.70 |
| 331.42 | 1.77 | 1.77 |
| 248.28 | 3.03 | 3.03 |
| 335.20 | 3.02 | 3.02 |
| 361.40 | 4.27 | 4.27 |
| 223.28 | 3.01 | 3.01 |
| 294.38 | 3.74 | 3.74 |
| 350.37 | 4.33 | 4.33 |
| 256.31 | 4.45 | 4.45 |
| 292.75 | 2.94 | 2.94 |
| 335.39 | 4.51 | 4.51 |
| 320.37 | 3.83 | 3.83 |
| 354.59 | 3.18 | 3.18 |
| 314.67 | 4.81 | 4.81 |
| 352.54 | 5.31 | 5.31 |
| 255.30 | 3.32 | 3.32 |
| 277.35 | 3.79 | 3.79 |
| 273.29 | 3.86 | 3.86 |
| 533.65 | 3.96 | 3.96 |
| 319.74 | 3.37 | 3.37 |
| 258.71 | 3.66 | 3.66 |
| 252.27 | 3.39 | 3.39 |
| 304.46 | 4.37 | 4.37 |
| 337.38 | 5.43 | 5.43 |
| 405.16 | 3.82 | 3.82 |
| 222.29 | 3.62 | 3.62 |
| 367.43 | 4.26 | 4.26 |
| 273.29 | 3.40 | 3.40 |
| 277.44 | 3.98 | 3.98 |
| 263.30 | 3.19 | 3.19 |
| 270.72 | 4.10 | 4.10 |
| 319.41 | 3.39 | 3.39 |
| 271.32 | 4.09 | 4.09 |
| 256.33 | 3.09 | 3.09 |
| 237.31 | 3.32 | 3.32 |
| 271.35 | 2.88 | 2.88 |
| 416.35 | 3.32 | 3.32 |
| 266.30 | 1.93 | 1.93 |
| 271.28 | 1.11 | 1.11 |
| 401.53 | 3.81 | 3.81 |
| 369.48 | 3.96 | 3.96 |
| 317.44 | 4.02 | 4.02 |
| 257.31 | 3.68 | 3.68 |
| 497.50 | 1.02 | 1.02 |
| 276.32 | 2.44 | 2.44 |
| 294.40 | 5.23 | 5.23 |
| 385.53 | 3.49 | 3.49 |
| 255.27 | 2.98 | 2.98 |
| 405.55 | 1.97 | 1.97 |
| 295.26 | 4.05 | 4.05 |
| 238.32 | 3.87 | 3.87 |
| 468.58 | 3.44 | 3.44 |
| 313.38 | 3.07 | 3.07 |
| 335.41 | 4.15 | 4.15 |
| 366.37 | 2.41 | 2.41 |
| 258.36 | 2.10 | 2.10 |
| 297.38 | 3.96 | 3.96 |
| 391.34 | 1.89 | 1.89 |
| 343.38 | 3.88 | 3.88 |
| 270.72 | 3.04 | 3.04 |
| 294.38 | 4.04 | 4.04 |
| 304.76 | 3.30 | 3.30 |
| 287.39 | 3.67 | 3.67 |
| 251.33 | 3.49 | 3.49 |
| 371.82 | 2.48 | 2.48 |
| 327.34 | 1.80 | 1.80 |
| 254.31 | 3.55 | 3.55 |
| 274.32 | 4.16 | 4.16 |
| 347.42 | 3.70 | 3.70 |
| 273.29 | 3.40 | 3.40 |
| 251.33 | 3.49 | 3.49 |
| 301.69 | 3.97 | 3.97 |
| 303.32 | 3.43 | 3.43 |
| 309.35 | 3.49 | 3.49 |
| 290.32 | -0.02 | -0.02 |
| 308.82 | 4.57 | 4.57 |
| 378.46 | 3.98 | 3.98 |
| 471.33 | 5.42 | 5.42 |
| 344.29 | 2.21 | 2.21 |
| 270.72 | 4.10 | 4.10 |
| 255.25 | 2.70 | 2.70 |
| 273.38 | 4.01 | 4.01 |
| 252.30 | 3.95 | 3.95 |
| 188.19 | 3.40 | 3.40 |
| 247.29 | 3.70 | 3.70 |
| 247.30 | 4.06 | 4.06 |
| 356.42 | 4.36 | 4.36 |
| 337.78 | 2.56 | 2.56 |
| 291.15 | 3.40 | 3.40 |
| 331.37 | 1.32 | 1.32 |
| 376.25 | 2.35 | 2.35 |
| 285.30 | 2.19 | 2.19 |
| 256.22 | -0.15 | -0.15 |
| 282.73 | 4.02 | 4.02 |
| 372.90 | 3.03 | 3.03 |
| 270.34 | 4.89 | 4.89 |
| 236.27 | 3.45 | 3.45 |
| 270.34 | 4.89 | 4.89 |
| 235.29 | 3.09 | 3.09 |
| 419.36 | 3.82 | 3.82 |
| 412.97 | 4.97 | 4.97 |
| 360.41 | 4.19 | 4.19 |
| 380.37 | 3.07 | 3.07 |
| 236.23 | 1.07 | 1.07 |
| 386.50 | 4.08 | 4.08 |
| 342.37 | 5.48 | 5.48 |
| 366.46 | 4.52 | 4.52 |
| 524.62 | 3.04 | 3.04 |
| 324.38 | 5.34 | 5.34 |
| 419.53 | 4.70 | 4.70 |
| 501.46 | 0.17 | 0.17 |
| 374.90 | 6.46 | 6.46 |
| 259.27 | 1.46 | 1.46 |
| 259.31 | 4.01 | 4.01 |
| 397.48 | 1.46 | 1.46 |
| 296.29 | 2.00 | 2.00 |
| 302.31 | 2.64 | 2.64 |
| 443.55 | 4.82 | 4.82 |
| 174.24 | 2.90 | 2.90 |
| 273.39 | 4.11 | 4.11 |
| 271.32 | 3.86 | 3.86 |
| 296.76 | 4.04 | 4.04 |
| 465.30 | 7.03 | 7.03 |
| 397.43 | 5.23 | 5.23 |
| 266.28 | 3.21 | 3.21 |
| 246.23 | 0.10 | 0.10 |
| 499.61 | 7.62 | 7.62 |
| 260.30 | 3.16 | 3.16 |
| 308.41 | 3.66 | 3.66 |
| 369.39 | 5.37 | 5.37 |
| 258.30 | 3.45 | 3.45 |
| 339.32 | 3.83 | 3.83 |
| 535.67 | 3.87 | 3.87 |
| 261.67 | -0.88 | -0.88 |
| 245.28 | 2.20 | 2.20 |
| 296.21 | 1.42 | 1.42 |
| 499.58 | 5.14 | 5.14 |
| 187.27 | 1.42 | 1.42 |
| 558.66 | 4.63 | 4.63 |
| 284.38 | 3.71 | 3.71 |
| 309.25 | 3.24 | 3.24 |
| 277.33 | 3.78 | 3.78 |
| 311.30 | 3.40 | 3.40 |
| 258.30 | 2.57 | 2.57 |
| 299.33 | 2.95 | 2.95 |
| 325.39 | 2.48 | 2.48 |
| 342.40 | 2.13 | 2.13 |
| 263.30 | 2.50 | 2.50 |
| 259.36 | 3.80 | 3.80 |
| 297.34 | 3.47 | 3.47 |
| 294.76 | 3.85 | 3.85 |
| 318.38 | 3.24 | 3.24 |
| 279.30 | 3.66 | 3.66 |
| 248.33 | 4.45 | 4.45 |
| 281.38 | 5.06 | 5.06 |
| 299.36 | 3.46 | 3.46 |
| 263.30 | 3.39 | 3.39 |
| 310.38 | 3.70 | 3.70 |
| 320.33 | 4.41 | 4.41 |
| 353.81 | 3.05 | 3.05 |
| 339.42 | 2.77 | 2.77 |