Basic Information
ID: ALA3215025
Type: Functional
Description: PubChem BioAssay. Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_Dose_CherryPick_Activity_Set2. (absACnn = the concentration at which the curve crosses threshold nn uM) (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215025
AbsAC40_uM
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 222.25 | 0.08 | 0.08 |
| 393.44 | 3.63 | 3.63 |
| 227.29 | 3.05 | 3.05 |
| 410.51 | 1.52 | 1.52 |
| 257.31 | 3.06 | 3.06 |
| 273.29 | 4.01 | 4.01 |
| 339.40 | 0.89 | 0.89 |
| 412.47 | 3.34 | 3.34 |
| 352.91 | 3.97 | 3.97 |
| 429.95 | 3.17 | 3.17 |
| 324.81 | 4.79 | 4.79 |
| 299.46 | 4.11 | 4.11 |
| 363.42 | 3.54 | 3.54 |
| 296.33 | 2.53 | 2.53 |
| 346.39 | 3.69 | 3.69 |
| 399.31 | 2.61 | 2.61 |
| 325.39 | 0.96 | 0.96 |
| 367.41 | 4.73 | 4.73 |
| 259.31 | 3.50 | 3.50 |
| 328.83 | 2.24 | 2.24 |
| 426.30 | 5.56 | 5.56 |
| 493.54 | 1.17 | 1.17 |
| 426.33 | 4.23 | 4.23 |
| 498.61 | 3.84 | 3.84 |
| 387.44 | 5.09 | 5.09 |
| 311.43 | 4.79 | 4.79 |
| 397.46 | 4.42 | 4.42 |
| 277.35 | 3.33 | 3.33 |
| 380.35 | 4.29 | 4.29 |
| 360.46 | 3.56 | 3.56 |
| 292.37 | 3.30 | 3.30 |
| 488.52 | 4.37 | 4.37 |
| 394.47 | 3.16 | 3.16 |
| 318.34 | 3.57 | 3.57 |
| 392.46 | 3.07 | 3.07 |
| 385.84 | 3.25 | 3.25 |
| 275.78 | 3.89 | 3.89 |
| 347.37 | 3.59 | 3.59 |
| 374.44 | 4.46 | 4.46 |
| 420.49 | 4.80 | 4.80 |
| 353.42 | 4.07 | 4.07 |
| 351.79 | 4.58 | 4.58 |
| 305.38 | 1.07 | 1.07 |
| 229.72 | 2.17 | 2.17 |
| 379.85 | 3.28 | 3.28 |
| 463.58 | 4.16 | 4.16 |
| 459.96 | 3.93 | 3.93 |
| 352.52 | 6.34 | 6.34 |
| 292.38 | 4.75 | 4.75 |
| 334.42 | 2.30 | 2.30 |
| 465.35 | 4.75 | 4.75 |
| 293.33 | 3.11 | 3.11 |
| 307.35 | 3.86 | 3.86 |
| 344.48 | 3.27 | 3.27 |
| 392.46 | 3.29 | 3.29 |
| 426.29 | 5.35 | 5.35 |
| 353.77 | 4.72 | 4.72 |
| 285.29 | 3.69 | 3.69 |
| 458.90 | 3.24 | 3.24 |
| 323.38 | 3.34 | 3.34 |
| 353.41 | 2.72 | 2.72 |
| 398.87 | 5.37 | 5.37 |
| 271.27 | 2.12 | 2.12 |
| 422.47 | 2.30 | 2.30 |
| 392.48 | 4.08 | 4.08 |
| 287.32 | 1.37 | 1.37 |
| 397.48 | 3.04 | 3.04 |
| 342.35 | 3.75 | 3.75 |
| 332.79 | 5.74 | 5.74 |
| 320.19 | 4.02 | 4.02 |
| 458.07 | 5.39 | 5.39 |
| 330.34 | 2.79 | 2.79 |
| 477.37 | 5.01 | 5.01 |
| 293.36 | 3.22 | 3.22 |
| 421.43 | 5.24 | 5.24 |
| 279.37 | 1.60 | 1.60 |
| 460.70 | 6.05 | 6.05 |
| 333.41 | 2.45 | 2.45 |
| 348.43 | 5.05 | 5.05 |
| 335.36 | 2.43 | 2.43 |
| 277.32 | 1.36 | 1.36 |
| 381.41 | 5.35 | 5.35 |
| 435.33 | 4.64 | 4.64 |
| 364.26 | 5.76 | 5.76 |
| 443.25 | 3.65 | 3.65 |
| 367.21 | 3.95 | 3.95 |
| 440.81 | 5.11 | 5.11 |
| 364.86 | 2.63 | 2.63 |
| 455.34 | 5.29 | 5.29 |
| 336.39 | 3.24 | 3.24 |
| 399.42 | 0.01 | 0.01 |
| 303.71 | 3.54 | 3.54 |
| 296.76 | 4.90 | 4.90 |
| 222.25 | 3.00 | 3.00 |
| 502.06 | 3.41 | 3.41 |
| 366.42 | 3.61 | 3.61 |
| 410.43 | 4.42 | 4.42 |
| 286.28 | 2.55 | 2.55 |
| 494.54 | 3.97 | 3.97 |
| 314.38 | 1.04 | 1.04 |
| 368.46 | 3.86 | 3.86 |
| 360.22 | 3.86 | 3.86 |
| 418.54 | 4.41 | 4.41 |
| 349.35 | 4.08 | 4.08 |
| 411.48 | 3.18 | 3.18 |
| 417.48 | 3.19 | 3.19 |
| 433.31 | 3.22 | 3.22 |
| 488.05 | 4.35 | 4.35 |
| 329.83 | 2.50 | 2.50 |
| 325.48 | 3.84 | 3.84 |
| 297.26 | 2.28 | 2.28 |
| 362.39 | 2.24 | 2.24 |
| 330.41 | 3.46 | 3.46 |
| 371.48 | 5.62 | 5.62 |
| 445.40 | 3.16 | 3.16 |
| 435.28 | 5.18 | 5.18 |
| 389.40 | 3.70 | 3.70 |
| 402.47 | 3.70 | 3.70 |
| 448.91 | 4.91 | 4.91 |
| 457.31 | 5.59 | 5.59 |
| 344.42 | 3.60 | 3.60 |
| 351.62 | 5.90 | 5.90 |
| 358.47 | 2.41 | 2.41 |
| 506.62 | 4.66 | 4.66 |
| 337.34 | 2.76 | 2.76 |
| 333.40 | 1.79 | 1.79 |
| 292.25 | 1.99 | 1.99 |
| 293.34 | 3.00 | 3.00 |
| 353.42 | 2.87 | 2.87 |
| 219.29 | 1.78 | 1.78 |
| 320.85 | 4.60 | 4.60 |
| 375.88 | 4.72 | 4.72 |
| 288.73 | 2.94 | 2.94 |
| 407.86 | 3.49 | 3.49 |
| 315.35 | 3.92 | 3.92 |
| 312.44 | 3.62 | 3.62 |
| 309.23 | 2.88 | 2.88 |
| 472.85 | 5.36 | 5.36 |
| 300.34 | 2.36 | 2.36 |
| 250.26 | 1.46 | 1.46 |
| 428.29 | 3.99 | 3.99 |
| 252.28 | 0.96 | 0.96 |
| 432.48 | 4.77 | 4.77 |
| 433.88 | 3.10 | 3.10 |
| 361.35 | 4.33 | 4.33 |
| 464.50 | 3.56 | 3.56 |
| 267.42 | 3.88 | 3.88 |
| 375.48 | 3.39 | 3.39 |
| 299.26 | 2.60 | 2.60 |
| 284.32 | 0.79 | 0.79 |
| 387.50 | 4.78 | 4.78 |
| 392.44 | 4.66 | 4.66 |
| 454.53 | 6.42 | 6.42 |
| 466.47 | 5.94 | 5.94 |
| 375.33 | 5.13 | 5.13 |
| 416.50 | 2.90 | 2.90 |
| 394.00 | 4.32 | 4.32 |
| 345.83 | 2.16 | 2.16 |
| 397.44 | 2.78 | 2.78 |
| 427.48 | 4.68 | 4.68 |
| 291.36 | 0.82 | 0.82 |
| 414.26 | 3.20 | 3.20 |
| 359.39 | 3.26 | 3.26 |
| 311.47 | 5.10 | 5.10 |
| 521.70 | 6.81 | 6.81 |
| 328.38 | 2.96 | 2.96 |
| 366.23 | 5.19 | 5.19 |
| 372.38 | 4.78 | 4.78 |
| 374.85 | 4.30 | 4.30 |
| 404.47 | 2.99 | 2.99 |
| 483.94 | 4.40 | 4.40 |
| 323.33 | 3.58 | 3.58 |
| 309.12 | 1.73 | 1.73 |
| 260.27 | 2.87 | 2.87 |
| 412.40 | 3.34 | 3.34 |
| 385.81 | 2.59 | 2.59 |
| 451.50 | 2.80 | 2.80 |
| 422.46 | 5.51 | 5.51 |
| 342.14 | 1.92 | 1.92 |
| 519.52 | 5.00 | 5.00 |
| 601.24 | 5.72 | 5.72 |
| 433.47 | 2.85 | 2.85 |
| 434.75 | 3.46 | 3.46 |
| 428.53 | 3.39 | 3.39 |
| 499.47 | 3.07 | 3.07 |
| 342.38 | 2.40 | 2.40 |
| 350.37 | 3.86 | 3.86 |
| 364.43 | 4.30 | 4.30 |
| 369.22 | 4.07 | 4.07 |
| 465.77 | 5.94 | 5.94 |
| 289.38 | 4.02 | 4.02 |
| 322.36 | 2.55 | 2.55 |
| 261.29 | 0.51 | 0.51 |
| 398.85 | 4.48 | 4.48 |
| 466.42 | 4.81 | 4.81 |
| 420.90 | 4.64 | 4.64 |
| 339.65 | 4.75 | 4.75 |
| 495.57 | 4.55 | 4.55 |
| 348.37 | 4.83 | 4.83 |
| 299.29 | 2.90 | 2.90 |
| 375.43 | 3.18 | 3.18 |
| 563.65 | 4.19 | 4.19 |
| 306.21 | 3.57 | 3.57 |
| 355.52 | 5.40 | 5.40 |
| 339.78 | 5.01 | 5.01 |
| 334.21 | 4.33 | 4.33 |
| 416.31 | 4.65 | 4.65 |
| 240.65 | -0.01 | -0.01 |
| 334.81 | 4.40 | 4.40 |
| 348.30 | 4.87 | 4.87 |
| 443.53 | 3.85 | 3.85 |
| 363.42 | 3.54 | 3.54 |
| 371.78 | 1.97 | 1.97 |
| 468.56 | 4.10 | 4.10 |
| 372.39 | 3.05 | 3.05 |
| 427.49 | 2.94 | 2.94 |
| 463.50 | 0.80 | 0.80 |
| 340.17 | 2.84 | 2.84 |
| 401.47 | 5.20 | 5.20 |
| 351.48 | 5.06 | 5.06 |
| 245.28 | 3.19 | 3.19 |
| 398.25 | 5.35 | 5.35 |
| 343.40 | 3.26 | 3.26 |
| 385.94 | 4.71 | 4.71 |
| 278.34 | 1.78 | 1.78 |
| 324.45 | 4.90 | 4.90 |
| 375.43 | 3.74 | 3.74 |
| 424.46 | 3.34 | 3.34 |
| 321.43 | 1.85 | 1.85 |
| 387.39 | 3.73 | 3.73 |
| 290.30 | 3.40 | 3.40 |
| 351.21 | 4.03 | 4.03 |
| 320.39 | 2.14 | 2.14 |
| 263.32 | 2.50 | 2.50 |
| 344.37 | 3.48 | 3.48 |
| 339.42 | 3.85 | 3.85 |
| 421.50 | 4.87 | 4.87 |
| 337.38 | 2.13 | 2.13 |
| 291.36 | 3.54 | 3.54 |
| 421.52 | 3.97 | 3.97 |
| 455.39 | 5.80 | 5.80 |
| 474.58 | 3.09 | 3.09 |
| 462.51 | 3.39 | 3.39 |
| 419.51 | 4.14 | 4.14 |
| 224.27 | 2.21 | 2.21 |
| 432.54 | 4.39 | 4.39 |
| 446.55 | 5.70 | 5.70 |
| 408.94 | 5.05 | 5.05 |
| 273.29 | 0.98 | 0.98 |
| 387.48 | 4.33 | 4.33 |
| 364.43 | 3.59 | 3.59 |
| 251.29 | 1.24 | 1.24 |
| 275.31 | 2.07 | 2.07 |
| 433.59 | 6.36 | 6.36 |
| 615.22 | 4.96 | 4.96 |
| 362.52 | 4.31 | 4.31 |
| 283.29 | 2.82 | 2.82 |
| 494.50 | 3.12 | 3.12 |
| 323.78 | 4.98 | 4.98 |
| 383.37 | 5.97 | 5.97 |
| 392.46 | 3.11 | 3.11 |
| 335.34 | 3.45 | 3.45 |
| 269.34 | 2.96 | 2.96 |
| 254.72 | 4.26 | 4.26 |
| 418.36 | 5.26 | 5.26 |
| 452.39 | 5.94 | 5.94 |
| 450.58 | 3.27 | 3.27 |
| 255.75 | 1.59 | 1.59 |
| 447.00 | 4.93 | 4.93 |
| 404.44 | 3.15 | 3.15 |
| 379.55 | 6.24 | 6.24 |
| 421.67 | 4.97 | 4.97 |
| 389.42 | 4.43 | 4.43 |
| 400.43 | 5.25 | 5.25 |
| 460.53 | 4.53 | 4.53 |
| 402.52 | 5.64 | 5.64 |
| 265.32 | 3.43 | 3.43 |
| 362.30 | 3.44 | 3.44 |
| 428.51 | 3.63 | 3.63 |
| 548.68 | 5.01 | 5.01 |
| 340.42 | 3.53 | 3.53 |
| 227.27 | 2.70 | 2.70 |
| 304.39 | 4.28 | 4.28 |
| 417.86 | 4.20 | 4.20 |
| 351.39 | 3.16 | 3.16 |
| 449.48 | 4.19 | 4.19 |
| 411.30 | 4.04 | 4.04 |
| 405.97 | 2.94 | 2.94 |
| 243.26 | 2.98 | 2.98 |
| 350.48 | 3.46 | 3.46 |
| 494.54 | 4.70 | 4.70 |
| 339.42 | 3.85 | 3.85 |
| 279.72 | 3.84 | 3.84 |
| 429.52 | 3.27 | 3.27 |
| 373.52 | 6.18 | 6.18 |
| 266.30 | 3.31 | 3.31 |
| 245.28 | 3.19 | 3.19 |
| 245.28 | 3.19 | 3.19 |
| 447.62 | 5.09 | 5.09 |
| 390.37 | 4.43 | 4.43 |
| 336.43 | 3.02 | 3.02 |
| 410.47 | 4.24 | 4.24 |
| 407.51 | 5.08 | 5.08 |
| 250.29 | 2.80 | 2.80 |
| 414.57 | 6.41 | 6.41 |
| 354.41 | 3.76 | 3.76 |
| 297.36 | 5.25 | 5.25 |
| 424.50 | 3.07 | 3.07 |
| 296.16 | 2.77 | 2.77 |
| 403.55 | 6.18 | 6.18 |
| 273.33 | 3.81 | 3.81 |
| 378.45 | 2.24 | 2.24 |
| 387.46 | 4.41 | 4.41 |
| 416.41 | 4.78 | 4.78 |
| 335.43 | 2.53 | 2.53 |
| 402.38 | 4.91 | 4.91 |
| 350.42 | 4.74 | 4.74 |
| 347.37 | 0.52 | 0.52 |
| 271.34 | 3.98 | 3.98 |
| 417.26 | 4.38 | 4.38 |
| 476.62 | 4.87 | 4.87 |
| 495.51 | 4.55 | 4.55 |
| 398.45 | 5.39 | 5.39 |
| 428.45 | 5.02 | 5.02 |
| 339.42 | 1.44 | 1.44 |
| 407.74 | 5.83 | 5.83 |
| 259.70 | 2.51 | 2.51 |
| 378.42 | 4.93 | 4.93 |
| 361.44 | 3.49 | 3.49 |
| 246.66 | 2.44 | 2.44 |
| 319.77 | 2.09 | 2.09 |
| 374.51 | 5.53 | 5.53 |
| 328.33 | 3.14 | 3.14 |
| 302.79 | 3.60 | 3.60 |
| 234.25 | 2.93 | 2.93 |
| 336.39 | 4.43 | 4.43 |
| 349.48 | 2.89 | 2.89 |
| 404.46 | 4.52 | 4.52 |
| 200.67 | 1.92 | 1.92 |
| 467.01 | 3.71 | 3.71 |
| 272.33 | 1.50 | 1.50 |
| 380.54 | 4.08 | 4.08 |
| 382.55 | 4.39 | 4.39 |
| 302.33 | 0.94 | 0.94 |
| 403.35 | 5.63 | 5.63 |
| 352.23 | 2.96 | 2.96 |
| 265.34 | 3.54 | 3.54 |
| 359.84 | 3.63 | 3.63 |
| 356.42 | 4.88 | 4.88 |
| 256.35 | 3.19 | 3.19 |
| 439.36 | 6.44 | 6.44 |
| 439.48 | 1.47 | 1.47 |
| 397.46 | 2.00 | 2.00 |
| 397.44 | 1.76 | 1.76 |
| 284.32 | 2.46 | 2.46 |
| 509.53 | 4.94 | 4.94 |
| 381.46 | 4.22 | 4.22 |
| 376.89 | 4.93 | 4.93 |
| 448.38 | 3.65 | 3.65 |
| 388.50 | 4.23 | 4.23 |
| 417.47 | 3.44 | 3.44 |
| 349.87 | 3.57 | 3.57 |
| 305.77 | 4.51 | 4.51 |
| 246.26 | 2.48 | 2.48 |
| 410.54 | 5.16 | 5.16 |
| 385.42 | 4.66 | 4.66 |
| 376.49 | 4.93 | 4.93 |
| 428.87 | 4.60 | 4.60 |
| 392.42 | 3.97 | 3.97 |
| 344.41 | 4.19 | 4.19 |
| 476.56 | 2.26 | 2.26 |
| 599.57 | 6.00 | 6.00 |
| 389.28 | 5.09 | 5.09 |
| 484.47 | 5.42 | 5.42 |
| 608.50 | 6.17 | 6.17 |
| 304.87 | 5.41 | 5.41 |
| 478.51 | 5.15 | 5.15 |
| 569.66 | 5.98 | 5.98 |
| 460.98 | 3.65 | 3.65 |
| 462.51 | 5.07 | 5.07 |
| 448.49 | 5.14 | 5.14 |
| 241.25 | 1.01 | 1.01 |
| 509.60 | 4.61 | 4.61 |
| 336.80 | 3.59 | 3.59 |
| 480.50 | 5.21 | 5.21 |
| 449.55 | 4.59 | 4.59 |
| 466.48 | 5.28 | 5.28 |
| 382.44 | 4.35 | 4.35 |
| 476.54 | 5.46 | 5.46 |
| 308.77 | 4.26 | 4.26 |
| 487.43 | 3.97 | 3.97 |
| 357.43 | 3.92 | 3.92 |
| 608.69 | 6.12 | 6.12 |
| 437.47 | 5.34 | 5.34 |
| 376.45 | 4.57 | 4.57 |
| 309.79 | 3.29 | 3.29 |
| 451.49 | 5.65 | 5.65 |
| 479.40 | 3.22 | 3.22 |
| 451.49 | 5.65 | 5.65 |
| 463.50 | 5.85 | 5.85 |
| 439.52 | 4.56 | 4.56 |
| 541.55 | 6.00 | 6.00 |
| 327.41 | 3.35 | 3.35 |
| 401.49 | 4.77 | 4.77 |
| 451.55 | 2.87 | 2.87 |
| 302.77 | 2.74 | 2.74 |
| 374.44 | 3.66 | 3.66 |
| 358.46 | 4.43 | 4.43 |
| 372.49 | 4.74 | 4.74 |
| 527.97 | 6.51 | 6.51 |
| 487.64 | 4.69 | 4.69 |
| 527.97 | 6.51 | 6.51 |
| 400.52 | 4.31 | 4.31 |
| 418.56 | 4.10 | 4.10 |
| 516.68 | 4.12 | 4.12 |
| 388.49 | 4.44 | 4.44 |
| 466.65 | 3.62 | 3.62 |
| 448.49 | 5.26 | 5.26 |
| 434.55 | 4.41 | 4.41 |
| 485.43 | 5.30 | 5.30 |
| 516.68 | 4.12 | 4.12 |
| 400.52 | 4.31 | 4.31 |
| 376.45 | 4.57 | 4.57 |
| 401.46 | 4.44 | 4.44 |
| 430.57 | 4.29 | 4.29 |
| 372.49 | 4.74 | 4.74 |
| 432.53 | 4.82 | 4.82 |
| 558.00 | 6.52 | 6.52 |
| 484.62 | 4.66 | 4.66 |
| 452.45 | 5.06 | 5.06 |
| 401.43 | 4.71 | 4.71 |
| 434.55 | 4.41 | 4.41 |
| 491.62 | 5.02 | 5.02 |
| 376.45 | 4.57 | 4.57 |
| 252.31 | 2.53 | 2.53 |
| 499.46 | 5.69 | 5.69 |
| 597.70 | 6.83 | 6.83 |
| 541.55 | 6.00 | 6.00 |
| 384.50 | 4.94 | 4.94 |
| 374.53 | 4.51 | 4.51 |
| 358.46 | 4.43 | 4.43 |
| 627.65 | 7.05 | 7.05 |
| 530.64 | 4.53 | 4.53 |
| 625.81 | 5.18 | 5.18 |
| 463.50 | 5.85 | 5.85 |
| 463.50 | 5.85 | 5.85 |
| 565.59 | 5.84 | 5.84 |
| 482.93 | 6.16 | 6.16 |
| 466.48 | 5.14 | 5.14 |
| 426.56 | 4.81 | 4.81 |
| 633.79 | 8.18 | 8.18 |
| 372.49 | 4.74 | 4.74 |
| 561.53 | 6.87 | 6.87 |
| 422.53 | 3.93 | 3.93 |
| 466.48 | 5.14 | 5.14 |
| 398.48 | 4.58 | 4.58 |
| 498.69 | 3.98 | 3.98 |
| 484.62 | 4.66 | 4.66 |
| 478.51 | 5.01 | 5.01 |
| 518.72 | 3.89 | 3.89 |
| 543.63 | 5.72 | 5.72 |
| 513.66 | 1.88 | 1.88 |
| 434.54 | 4.12 | 4.12 |
| 371.48 | 4.31 | 4.31 |
| 451.49 | 5.65 | 5.65 |
| 373.52 | 4.25 | 4.25 |
| 426.56 | 4.81 | 4.81 |
| 396.08 | 4.37 | 4.37 |
| 330.41 | 3.19 | 3.19 |
| 324.20 | 3.06 | 3.06 |
| 339.36 | 1.60 | 1.60 |
| 354.26 | 4.24 | 4.24 |
| 339.36 | 1.86 | 1.86 |
| 417.47 | 3.84 | 3.84 |
| 419.48 | 4.62 | 4.62 |
| 377.40 | 3.42 | 3.42 |
| 342.40 | 2.93 | 2.93 |
| 341.39 | 4.68 | 4.68 |
| 304.39 | 3.64 | 3.64 |
| 553.00 | 4.29 | 4.29 |
| 466.39 | 3.11 | 3.11 |
| 308.17 | 4.15 | 4.15 |
| 494.58 | 6.03 | 6.03 |
| 330.39 | 2.14 | 2.14 |
| 362.35 | 1.46 | 1.46 |
| 390.83 | 5.17 | 5.17 |
| 410.91 | 4.29 | 4.29 |
| 331.33 | 3.24 | 3.24 |
| 329.40 | 2.70 | 2.70 |
| 365.46 | 4.51 | 4.51 |
| 392.11 | 4.97 | 4.97 |
| 414.33 | 5.27 | 5.27 |
| 330.35 | 3.59 | 3.59 |