Assay Report Card

Basic Information

ID: ALA3215038

Type: Functional

Description: PubChem BioAssay. Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Human Bronchial Epithelial Cells. Measured in Cell-Based System Using Plate Reader - 7017-01_Other_Dose_CherryPick_Activity. (Class of assay: confirmatory)

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
305.160.290.29
853.923.743.74
264.322.472.47
238.293.123.12
239.253.753.75
285.69-0.30-0.30
327.395.095.09
274.323.393.39
353.332.722.72
286.242.282.28
394.324.134.13
393.511.601.60
332.352.962.96
853.923.743.74
338.770.920.92
194.243.093.09
279.393.753.75
262.301.251.25
729.781.421.42
414.412.762.76
259.741.981.98
301.352.602.60
352.253.593.59
563.630.750.75
383.520.090.09
584.66-1.51-1.51
293.333.303.30
284.272.882.88
438.534.664.66
402.555.315.31
406.553.893.89
563.991.031.03
263.323.763.76
334.33-1.65-1.65
327.435.955.95
290.261.921.92
326.402.712.71
434.543.953.95
426.473.623.62
438.513.493.49
297.362.092.09
312.232.442.44
313.205.055.05
361.234.474.47
371.462.642.64
318.424.084.08
220.282.932.93
310.443.923.92
364.535.235.23
357.781.351.35
161.640.300.30
137.57-0.44-0.44
279.68-2.56-2.56
329.361.641.64
357.383.753.75
356.525.055.05
388.525.575.57
289.303.983.98
317.372.222.22
451.343.883.88
180.211.131.13
282.734.144.14
403.823.003.00
423.544.554.55
248.712.972.97
306.373.813.81
299.362.812.81
356.855.285.28
421.482.922.92
422.492.032.03
405.453.153.15
563.991.031.03
494.013.233.23
261.322.082.08
487.623.653.65
338.844.674.67
350.424.494.49
311.342.942.94
256.262.812.81
330.344.024.02
371.873.213.21
304.394.784.78
485.915.965.96
415.424.664.66
316.382.982.98
389.422.862.86
354.454.474.47
336.442.562.56
240.261.561.56
359.483.383.38
267.364.264.26
375.474.234.23
380.401.871.87
415.503.953.95
386.472.982.98
372.403.203.20
246.343.023.02
334.814.514.51
333.434.194.19
295.373.273.27
312.332.302.30
401.513.073.07
355.422.792.79
350.424.264.26
324.342.662.66
279.304.364.36
304.395.115.11
316.771.231.23
316.453.333.33
420.402.542.54
317.353.783.78
360.504.294.29
251.171.241.24
388.525.575.57
390.421.741.74
371.534.754.75
311.412.862.86
845.943.783.78
366.372.702.70
431.364.964.96
267.383.693.69
405.505.085.08
370.412.872.87
358.372.652.65
398.483.193.19
328.330.760.76
397.462.822.82
410.383.503.50
438.553.873.87
411.483.863.86
352.423.193.19
306.372.572.57
323.744.004.00
396.325.105.10
365.463.253.25
540.752.272.27
341.243.143.14
350.373.473.47
409.452.082.08
407.433.613.61
387.515.325.32
392.844.814.81
348.840.320.32
345.365.055.05
240.262.112.11
402.454.044.04
341.372.852.85
416.543.833.83
347.333.553.55
377.401.491.49
308.384.614.61
276.322.482.48
398.354.644.64
430.462.922.92
240.262.042.04
320.353.373.37
373.414.734.73
338.404.244.24
308.772.272.27
308.263.113.11
502.476.006.00
352.423.283.28
408.461.801.80
530.663.013.01
291.26-0.13-0.13
362.433.823.82
360.454.524.52
311.392.662.66
309.414.564.56
368.445.025.02
451.595.265.26
315.383.713.71
421.484.564.56
313.382.492.49
226.241.651.65
288.313.223.22
366.494.064.06
421.575.165.16
300.475.345.34
401.513.073.07
431.365.205.20
287.193.233.23
422.363.523.52
430.565.245.24
451.912.882.88
266.283.643.64
333.303.253.25
278.313.523.52
431.583.513.51
418.524.954.95
396.452.972.97
447.565.785.78
355.392.592.59
356.402.152.15
400.504.264.26
336.462.342.34
457.522.712.71
368.503.803.80
338.404.244.24
545.455.155.15
389.382.382.38
332.363.283.28
310.433.893.89
425.554.174.17
362.484.104.10
412.500.450.45
320.393.863.86
311.341.521.52
383.364.414.41
285.343.003.00
266.303.083.08
387.442.342.34
407.504.754.75
409.245.355.35
340.341.991.99
469.545.905.90
408.303.423.42
391.223.423.42
418.453.403.40
404.974.244.24
371.444.974.97
342.483.533.53
299.362.812.81
331.384.234.23
348.363.683.68
374.493.133.13
415.452.962.96
354.413.383.38
254.722.242.24
294.261.101.10
282.292.162.16
424.523.283.28
290.374.484.48
468.583.923.92
420.424.554.55
174.162.342.34
435.483.923.92
299.333.453.45
347.474.644.64
412.533.793.79
345.464.164.16
370.454.274.27
235.252.242.24
501.613.173.17
319.413.393.39
295.343.933.93
384.435.135.13
310.352.502.50
278.723.883.88
478.673.373.37
412.403.143.14
286.362.972.97
417.535.475.47
227.272.852.85
320.311.911.91
350.423.353.35
425.473.603.60
301.352.572.57
321.343.353.35
465.584.094.09
305.342.742.74
299.333.303.30
414.892.592.59
360.464.134.13
443.572.362.36
368.464.354.35
326.404.354.35
293.414.224.22
408.303.343.34
492.004.344.34
296.333.733.73
311.345.095.09
333.302.942.94
294.692.162.16
329.414.024.02
430.942.202.20
251.243.053.05
348.453.853.85
294.443.073.07
309.424.374.37
202.212.022.02
441.414.854.85
329.381.651.65
400.935.245.24
346.214.344.34
349.354.804.80
394.905.065.06
398.924.324.32
362.484.244.24
354.362.382.38
404.503.273.27
330.443.063.06
408.484.154.15
502.476.006.00
359.843.983.98
348.422.972.97
322.594.124.12
281.292.632.63
351.845.155.15
247.303.403.40
475.364.194.19
383.194.394.39
458.563.003.00
293.282.932.93
391.904.464.46
328.424.474.47
398.854.054.05
311.341.251.25
383.432.552.55
371.392.242.24
375.483.483.48
404.304.224.22
396.874.574.57
334.383.813.81
374.484.634.63
467.884.124.12
562.625.365.36
354.434.334.33
520.596.766.76
327.433.793.79
455.493.833.83
304.193.313.31
372.493.393.39
410.383.713.71
386.883.133.13
322.363.893.89
416.343.683.68
376.323.473.47
283.363.113.11
296.313.593.59
407.473.243.24
384.352.582.58
440.534.874.87
302.381.481.48
433.946.646.64
321.423.523.52
443.514.034.03
373.313.663.66
458.974.214.21
336.442.692.69
372.424.344.34
301.444.944.94
443.504.204.20
422.545.585.58
362.455.055.05
355.424.144.14
384.383.223.22
313.353.033.03
307.353.733.73
415.493.843.84
406.465.415.41
419.534.924.92
432.575.325.32
385.312.222.22
436.454.264.26
403.484.084.08
292.362.782.78
286.313.073.07
332.743.683.68
398.464.864.86
281.362.682.68
288.304.274.27
308.384.024.02
292.343.803.80
380.473.953.95
333.413.103.10
252.323.163.16
369.423.463.46
356.452.742.74
366.494.514.51
452.974.754.75
254.724.634.63
284.393.103.10
335.644.624.62
364.283.333.33
571.580.600.60
194.232.202.20
361.494.364.36
277.712.432.43
459.963.333.33
384.464.344.34
407.333.623.62
364.403.133.13
367.431.211.21
385.422.572.57
440.541.231.23
440.952.742.74
358.832.122.12
405.191.351.35
499.533.753.75
379.194.764.76
506.932.242.24
514.054.004.00
377.433.293.29
386.451.421.42
446.963.573.57
539.631.301.30
555.581.631.63
296.201.981.98
397.434.464.46
475.572.652.65
306.341.831.83
387.391.791.79
347.423.563.56
523.532.712.71
278.354.304.30
305.343.093.09
329.834.794.79
279.281.781.78
368.342.772.77
423.521.661.66
491.546.606.60
356.403.273.27
400.913.293.29
418.455.165.16
427.492.572.57
425.373.403.40
492.535.485.48
390.484.214.21
497.642.522.52
452.104.094.09
341.363.213.21
357.794.354.35
270.72-0.37-0.37
400.543.593.59
349.362.432.43
245.310.980.98
431.542.162.16
364.834.024.02
327.184.254.25
464.574.704.70
407.521.321.32
478.934.484.48
413.524.794.79
252.323.163.16
471.156.496.49
476.452.932.93
454.551.661.66
339.353.663.66
443.532.472.47
421.542.742.74
483.503.663.66
370.453.293.29
398.053.603.60
403.444.264.26
348.383.513.51
266.210.210.21
514.994.454.45
328.443.403.40
332.434.484.48
371.801.271.27
427.736.026.02
367.411.801.80
254.723.593.59
352.302.482.48
333.392.872.87
300.303.473.47
311.341.621.62
255.340.450.45
377.493.843.84
399.353.813.81
505.602.512.51
471.445.285.28
550.444.264.26
394.522.852.85
438.552.062.06
328.444.114.11
365.392.952.95
405.434.784.78
329.383.353.35
373.412.592.59
386.412.562.56
301.372.852.85
264.671.991.99
429.332.732.73
353.382.962.96
431.453.773.77
385.854.004.00
339.352.652.65
337.383.343.34
339.352.652.65
294.383.973.97
428.586.616.61
332.413.373.37
329.362.282.28
310.364.584.58
373.414.254.25
418.404.664.66
366.424.214.21
359.183.663.66
421.253.553.55
397.613.303.30
456.553.463.46
378.383.083.08
261.112.952.95
342.234.454.45
333.353.043.04
334.343.223.22
321.413.943.94
348.413.253.25
294.312.042.04
430.473.363.36
394.453.553.55
538.633.543.54
358.444.804.80
321.342.672.67
387.873.273.27
297.393.543.54
293.711.871.87
411.464.774.77
283.354.454.45
407.503.783.78
378.463.543.54
362.393.163.16
411.474.124.12
243.22-2.26-2.26
417.474.054.05
444.454.094.09
302.362.352.35
387.442.862.86
879.866.396.39
324.313.053.05
578.636.536.53
649.627.077.07
295.342.902.90
522.655.345.34
338.24-1.88-1.88
409.423.203.20
393.372.912.91
408.500.540.54
466.391.471.47
571.723.973.97
325.322.352.35
470.522.322.32
477.563.933.93
566.755.195.19
506.483.903.90
482.584.064.06
475.573.773.77
573.743.873.87
667.566.946.94
470.544.194.19
494.613.933.93
482.584.064.06
577.105.515.51
608.765.935.93
494.613.933.93
575.655.425.42
443.462.182.18
393.463.803.80
439.603.033.03
477.563.933.93
509.673.963.96
394.452.402.40
648.236.166.16
557.714.034.03
463.533.903.90
475.573.773.77
470.544.194.19
533.112.992.99
509.673.963.96
520.663.523.52
450.563.503.50
659.815.645.64
483.632.742.74
252.270.590.59
509.673.963.96
406.432.122.12
564.733.353.35
635.714.874.87
428.491.161.16
404.531.401.40
504.582.732.73
426.523.093.09
434.563.803.80
422.503.183.18
605.685.615.61
480.593.913.91
520.663.523.52
566.034.824.82
470.544.194.19
704.837.187.18
495.653.653.65
482.584.064.06
636.605.155.15
295.392.322.32
334.172.622.62
342.234.454.45
372.454.514.51
417.492.342.34
299.403.333.33
378.351.161.16
289.362.242.24
377.192.962.96
294.313.213.21
383.864.424.42
853.923.743.74
491.595.235.23
307.353.253.25
401.295.845.84
326.282.452.45
277.333.693.69
313.361.791.79
386.360.720.72
353.382.292.29