Assay Report Card

Basic Information

ID: ALA3215039

Type: Functional

Description: PubChem BioAssay. Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition Measured in Cell-Based System Using Plate Reader - 7011-01_Antagonist_Dose_CherryPick_Activity_Set2. (Class of assay: confirmatory)

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.26-1.38-1.38
258.323.993.99
287.164.074.07
240.333.853.85
327.343.053.05
288.313.363.36
252.273.473.47
307.26-1.29-1.29
242.303.773.77
254.363.943.94
294.291.831.83
286.241.091.09
253.313.143.14
432.503.033.03
265.273.053.05
299.334.474.47
270.724.374.37
292.093.153.15
272.313.663.66
297.350.160.16
259.314.114.11
241.313.973.97
253.262.812.81
282.303.423.42
317.283.803.80
271.713.473.47
316.793.353.35
475.635.115.11
414.784.454.45
342.814.264.26
300.793.573.57
279.344.104.10
302.333.863.86
316.364.174.17
241.082.542.54
255.102.852.85
238.252.932.93
534.065.035.03
339.444.254.25
308.372.602.60
387.182.412.41
340.455.335.33
366.854.894.89
277.332.602.60
257.292.512.51
295.343.603.60
322.412.992.99
517.63
283.333.333.33
270.292.622.62
329.382.232.23
288.282.872.87
299.773.073.07
403.372.412.41
402.792.912.91
284.321.571.57
273.293.083.08
248.311.861.86
262.273.113.11
295.352.242.24
518.595.465.46
279.302.792.79
275.303.203.20
262.313.803.80
345.414.014.01
394.414.054.05
300.703.763.76
386.222.172.17
460.585.505.50
295.303.003.00
313.353.193.19
335.772.372.37
317.403.533.53
436.924.494.49
321.383.663.66
235.25-0.67-0.67
525.514.084.08
288.262.562.56
283.363.963.96
292.723.113.11
333.774.004.00
343.383.913.91
362.464.114.11
324.293.033.03
267.364.264.26
382.344.194.19
268.322.592.59
309.352.952.95
324.172.142.14
237.262.592.59
284.343.313.31
283.333.333.33
262.292.122.12
445.375.185.18
422.532.582.58
337.433.593.59
468.984.214.21
280.283.413.41
269.303.023.02
401.513.013.01
331.374.614.61
302.333.703.70
294.403.433.43
279.783.863.86
394.544.854.85
253.375.095.09
304.395.115.11
320.373.933.93
396.383.423.42
371.534.754.75
324.164.024.02
481.513.633.63
370.422.762.76
243.272.202.20
265.323.383.38
450.132.502.50
321.433.893.89
293.373.053.05
382.493.523.52
246.343.263.26
303.753.673.67
282.311.051.05
310.313.313.31
265.322.842.84
453.525.005.00
285.302.712.71
287.753.293.29
264.312.172.17
364.523.623.62
226.242.672.67
269.343.063.06
250.303.703.70
256.334.154.15
327.173.123.12
291.293.023.02
319.311.851.85
286.293.043.04
341.352.922.92
330.393.843.84
340.454.144.14
281.313.643.64
404.502.442.44
350.343.633.63
307.263.833.83
285.333.363.36
443.933.673.67
448.102.382.38
307.143.693.69
284.343.963.96
271.713.763.76
283.723.963.96
349.183.433.43
316.382.802.80
365.454.934.93
267.364.264.26
269.344.184.18
260.301.511.51
434.502.812.81
331.793.903.90
337.301.991.99
278.291.891.89
253.263.223.22
319.311.851.85
291.332.642.64
320.331.891.89
338.363.133.13
324.363.643.64
315.384.384.38
261.372.742.74
360.863.693.69
276.322.482.48
259.383.443.44
246.292.062.06
289.362.022.02
280.332.882.88
232.312.872.87
310.313.313.31
292.383.743.74
324.815.005.00
384.493.763.76
273.363.763.76
349.304.504.50
310.363.093.09
238.293.643.64
318.403.263.26
404.473.543.54
329.832.502.50
331.183.453.45
317.773.083.08
251.213.023.02
283.313.123.12
308.392.852.85
290.713.683.68
404.813.163.16
324.343.233.23
371.412.942.94
230.293.423.42
281.272.902.90
298.302.852.85
401.464.134.13
309.353.773.77
262.313.813.81
288.301.821.82
425.494.654.65
330.433.503.50
251.293.423.42
294.312.822.82
365.420.460.46
323.353.413.41
311.413.923.92
279.352.812.81
336.402.422.42
272.302.592.59
251.293.123.12
325.393.483.48
292.363.073.07
297.272.772.77
315.352.022.02
301.372.832.83
267.292.372.37
300.302.122.12
342.902.312.31
240.271.371.37
313.363.963.96
360.442.712.71
523.626.656.65
405.313.803.80
257.723.673.67
318.383.383.38
425.365.935.93
328.732.482.48
301.781.721.72
269.302.392.39
300.382.982.98
219.272.102.10
487.653.733.73
282.753.123.12
431.454.624.62
251.293.793.79
305.384.054.05
451.926.076.07
290.713.683.68
251.293.993.99
385.924.564.56
301.423.343.34
266.303.083.08
296.282.522.52
513.405.785.78
368.464.524.52
392.444.664.66
294.403.433.43
415.525.885.88
256.283.463.46
190.161.851.85
311.343.203.20
555.655.245.24
344.442.772.77
270.322.652.65
278.313.503.50
301.333.063.06
324.433.353.35
288.333.543.54
267.292.822.82
329.383.953.95
315.343.373.37
287.322.912.91
412.513.533.53
237.263.113.11
270.25-0.56-0.56
309.282.722.72
411.554.734.73
246.274.044.04
429.484.914.91
270.313.243.24
268.313.453.45
276.363.063.06
318.403.263.26
322.393.913.91
340.443.443.44
464.525.125.12
274.353.053.05
316.363.873.87
332.443.093.09
366.433.783.78
363.492.832.83
245.353.033.03
288.764.004.00
494.623.863.86
302.794.514.51
423.945.675.67
298.373.083.08
441.635.405.40
251.294.024.02
278.364.484.48
240.333.983.98
400.593.953.95
351.422.902.90
304.322.202.20
270.313.283.28
366.604.134.13
274.321.901.90
463.385.295.29
253.262.812.81
356.443.043.04
353.171.541.54
256.262.112.11
327.823.713.71
426.472.922.92
256.303.043.04
331.793.903.90
315.393.933.93
312.374.514.51
266.303.293.29
276.302.572.57
454.553.073.07
298.373.353.35
324.164.024.02
344.403.173.17
502.552.252.25
299.363.343.34
487.544.354.35
481.622.552.55
283.332.432.43
255.323.073.07
282.463.423.42
376.484.004.00
267.332.612.61
394.414.054.05
478.814.724.72
373.841.501.50
366.483.703.70
279.814.494.49
255.303.663.66
301.733.373.37
241.323.133.13
483.553.323.32
283.292.822.82
350.333.363.36
294.353.733.73
459.935.305.30
291.283.223.22
368.494.224.22
302.312.912.91
315.174.474.47
271.102.552.55
340.383.123.12
313.383.553.55
355.483.333.33
616.505.685.68
421.503.863.86
252.273.393.39
276.723.233.23
287.164.074.07
300.363.373.37
438.892.382.38
287.342.162.16
264.261.821.82
291.354.494.49
258.303.473.47
429.484.914.91
263.303.803.80
397.304.794.79
284.343.563.56
289.344.224.22
223.242.802.80
245.712.932.93
277.324.104.10
301.403.673.67
308.793.723.72
488.774.914.91
431.454.424.42
481.644.844.84
431.182.202.20
279.343.453.45
254.364.664.66
291.144.714.71
359.352.302.30
346.412.152.15
440.914.294.29
320.373.183.18
266.302.482.48
315.813.023.02
338.363.513.51
251.292.622.62
376.464.154.15
307.353.953.95
319.364.344.34
331.351.721.72
258.312.352.35
242.282.732.73
442.955.005.00
357.583.303.30
402.504.394.39
330.372.882.88
312.374.514.51
280.283.443.44
323.403.063.06
274.353.463.46
394.534.264.26
519.604.134.13
334.783.283.28
436.543.153.15
405.313.803.80
274.303.153.15
517.576.456.45
239.282.952.95
324.433.733.73
381.261.891.89
282.263.023.02
300.272.762.76
274.324.004.00
373.391.881.88
433.596.366.36
317.344.134.13
260.363.653.65
289.383.143.14
535.134.944.94
269.303.023.02
336.443.033.03
262.693.623.62
287.753.063.06
311.383.463.46
285.354.374.37
394.503.843.84
312.872.712.71
257.322.152.15
340.382.092.09
308.824.574.57
251.333.313.31
252.272.772.77
285.353.233.23
321.423.523.52
296.283.093.09
472.544.324.32
335.823.103.10
367.433.713.71
269.303.023.02
487.585.055.05
360.504.344.34
272.302.122.12
317.781.381.38
272.303.363.36
275.262.982.98
400.484.324.32
367.495.035.03
368.823.563.56
410.543.373.37
490.604.604.60
499.536.206.20
540.135.775.77
370.433.823.82
317.412.232.23
301.733.483.48
257.322.152.15
267.283.043.04
294.383.743.74
269.333.253.25
290.713.683.68
306.773.813.81
318.364.094.09
311.173.883.88
309.363.723.72
548.685.015.01
318.402.402.40
238.293.403.40
255.353.513.51
267.292.822.82
335.391.751.75
283.333.353.35
295.351.961.96
368.352.762.76
359.361.491.49
322.363.923.92
307.353.353.35
272.392.342.34
321.723.903.90
260.252.722.72
321.414.874.87
274.303.153.15
327.343.383.38
327.823.853.85
262.272.262.26
300.313.433.43
473.623.523.52
269.692.182.18
301.824.114.11
300.703.763.76
508.622.922.92
459.362.672.67
383.344.334.33
347.201.711.71
335.793.933.93
209.252.702.70
403.556.186.18
357.452.552.55
418.584.994.99
507.825.685.68
301.343.053.05
291.373.053.05
316.311.591.59
372.473.323.32
357.413.033.03
266.26-1.35-1.35
412.575.245.24
331.412.672.67
278.293.303.30
317.354.144.14
325.27-2.23-2.23
517.634.684.68
331.382.862.86
339.393.043.04
360.823.683.68
344.423.673.67
279.303.313.31
432.384.874.87
471.594.264.26
459.604.544.54
411.595.935.93
236.273.313.31
341.413.433.43
366.494.964.96
497.625.925.92
427.513.343.34
519.615.515.51
429.454.284.28
425.443.963.96
370.244.154.15
393.515.395.39
407.434.114.11
453.523.213.21
541.614.174.17
315.383.163.16
450.564.364.36
479.544.634.63
509.614.744.74
638.774.104.10
485.645.245.24
413.544.674.67
549.565.105.10
276.303.533.53
507.645.355.35
394.523.503.50
372.865.115.11
358.854.494.49
454.503.563.56
521.584.904.90
471.614.854.85
505.584.954.95
360.442.542.54
537.624.504.50
263.303.863.86
499.536.206.20
274.352.032.03
351.414.024.02
232.312.602.60
374.403.283.28
278.702.292.29
404.424.774.77
329.454.834.83
376.463.103.10
537.656.966.96
254.323.143.14
630.676.046.04
417.523.533.53
478.515.155.15
490.993.523.52
452.454.894.89
282.352.842.84
414.514.694.69
549.594.664.66
628.655.435.43
602.635.845.84
541.448.788.78
477.644.474.47
412.455.275.27
614.675.715.71
447.495.695.69
576.764.384.38
608.696.126.12
557.656.236.23
489.642.602.60
313.362.652.65
336.413.173.17
446.524.524.52
414.513.463.46
621.706.786.78
343.432.902.90
608.655.165.16
443.454.254.25
319.412.422.42
388.443.203.20
643.735.545.54
643.735.545.54
336.413.173.17
391.453.003.00
618.685.125.12
482.935.655.65
456.514.174.17
412.492.352.35
429.553.663.66
343.432.902.90
281.273.213.21
402.473.593.59
529.605.415.41
484.584.824.82
494.634.414.41
416.503.983.98
380.453.203.20
471.573.793.79
428.533.853.85
663.706.896.89
584.645.705.70
428.533.853.85
640.714.954.95
663.706.896.89
448.593.973.97
374.422.812.81
484.604.464.46
608.655.165.16
466.485.145.14
385.513.453.45
590.696.086.08
328.430.360.36
643.735.545.54
402.473.593.59
583.576.126.12
631.775.655.65
583.576.126.12
402.473.593.59
633.735.105.10
573.745.295.29
493.633.373.37
374.422.812.81
378.523.433.43
478.515.015.01
408.523.693.69
408.543.063.06
681.746.476.47
650.625.085.08
228.292.792.79
441.584.124.12
374.422.812.81
388.443.203.20
402.473.593.59
489.594.964.96
441.584.124.12
388.443.203.20
590.695.515.51
655.045.735.73
449.505.045.04
357.463.293.29
586.154.424.42
509.631.131.13
434.563.663.66
654.155.445.44
504.684.154.15
246.292.892.89
260.323.203.20
394.814.704.70
291.313.383.38