Basic Information
ID: ALA3215072
Type: Binding
Description: PubChem BioAssay. QFRET-based biochemical high throughput dose response assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2). (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215072
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.49 | -0.14 | -0.14 |
| 332.34 | 3.43 | 3.43 |
| 334.40 | 4.00 | 4.00 |
| 374.89 | 5.05 | 5.05 |
| 397.35 | 4.98 | 4.98 |
| 403.38 | 5.04 | 5.04 |
| 490.38 | 4.62 | 4.62 |
| 235.34 | 2.95 | 2.95 |
| 572.57 | 4.11 | 4.11 |
| 527.57 | 4.20 | 4.20 |
| 335.36 | 3.32 | 3.32 |
| 395.53 | 4.00 | 4.00 |
| 327.37 | 0.83 | 0.83 |
| 444.58 | 3.84 | 3.84 |
| 415.56 | 4.79 | 4.79 |
| 430.56 | 5.95 | 5.95 |
| 495.03 | 4.70 | 4.70 |
| 440.48 | 2.62 | 2.62 |
| 351.36 | 3.02 | 3.02 |
| 293.39 | 2.25 | 2.25 |
| 403.49 | 3.72 | 3.72 |
| 354.41 | 6.17 | 6.17 |
| 313.38 | 1.94 | 1.94 |
| 323.23 | 3.76 | 3.76 |
| 350.45 | 3.43 | 3.43 |
| 444.58 | 3.78 | 3.78 |
| 404.52 | 2.83 | 2.83 |
| 331.33 | 2.92 | 2.92 |
| 351.23 | 2.48 | 2.48 |
| 314.39 | 4.76 | 4.76 |
| 338.39 | 1.81 | 1.81 |
| 322.39 | 2.87 | 2.87 |
| 503.61 | 2.82 | 2.82 |
| 344.23 | 2.77 | 2.77 |
| 310.43 | 4.48 | 4.48 |
| 348.86 | 2.45 | 2.45 |
| 345.81 | 3.65 | 3.65 |
| 310.37 | 4.08 | 4.08 |
| 357.36 | 2.79 | 2.79 |
| 287.78 | 4.00 | 4.00 |
| 410.46 | 2.61 | 2.61 |
| 355.38 | 2.09 | 2.09 |
| 404.54 | 2.64 | 2.64 |
| 377.42 | 2.97 | 2.97 |
| 277.37 | 2.58 | 2.58 |
| 319.34 | 1.24 | 1.24 |
| 343.45 | 3.45 | 3.45 |
| 381.39 | 3.03 | 3.03 |
| 396.43 | 2.30 | 2.30 |
| 285.44 | 2.69 | 2.69 |
| 265.41 | 3.19 | 3.19 |
| 383.52 | 2.81 | 2.81 |
| 519.25 | 4.94 | 4.94 |
| 424.51 | 2.95 | 2.95 |
| 375.49 | 3.95 | 3.95 |
| 317.80 | 3.79 | 3.79 |
| 315.47 | 4.21 | 4.21 |
| 331.34 | 3.38 | 3.38 |
| 351.38 | 3.01 | 3.01 |
| 350.49 | 4.36 | 4.36 |
| 382.45 | 2.63 | 2.63 |
| 374.65 | 3.33 | 3.33 |
| 216.31 | 2.44 | 2.44 |
| 285.42 | 4.34 | 4.34 |
| 348.86 | 2.45 | 2.45 |
| 453.71 | 4.69 | 4.69 |
| 297.45 | 2.91 | 2.91 |
| 320.21 | 2.36 | 2.36 |
| 461.95 | 3.10 | 3.10 |
| 309.26 | 3.65 | 3.65 |
| 214.22 | 3.51 | 3.51 |
| 423.88 | 2.32 | 2.32 |
| 355.42 | 3.20 | 3.20 |
| 378.80 | 2.20 | 2.20 |
| 399.47 | 2.14 | 2.14 |
| 315.40 | 2.86 | 2.86 |
| 253.40 | 3.44 | 3.44 |
| 370.43 | 3.32 | 3.32 |
| 356.29 | 2.89 | 2.89 |
| 268.41 | 1.87 | 1.87 |
| 358.47 | 1.93 | 1.93 |
| 381.29 | 3.77 | 3.77 |
| 354.27 | 3.96 | 3.96 |
| 336.39 | 4.40 | 4.40 |
| 305.43 | 3.41 | 3.41 |
| 388.41 | 1.62 | 1.62 |
| 372.29 | 5.43 | 5.43 |
| 424.44 | 2.33 | 2.33 |
| 517.41 | -0.14 | -0.14 |
| 341.80 | 2.56 | 2.56 |
| 324.36 | 1.28 | 1.28 |
| 309.37 | 3.30 | 3.30 |
| 305.79 | 2.97 | 2.97 |
| 267.36 | 3.88 | 3.88 |
| 239.28 | 2.97 | 2.97 |
| 403.55 | 6.09 | 6.09 |
| 366.37 | 2.39 | 2.39 |
| 404.54 | 2.89 | 2.89 |
| 313.38 | 1.94 | 1.94 |
| 327.80 | 1.70 | 1.70 |
| 378.80 | 2.20 | 2.20 |
| 283.38 | 3.65 | 3.65 |
| 343.41 | 1.95 | 1.95 |
| 336.25 | 4.59 | 4.59 |
| 381.39 | 3.03 | 3.03 |
| 357.42 | 4.39 | 4.39 |
| 367.81 | 2.04 | 2.04 |
| 368.49 | 4.79 | 4.79 |
| 353.84 | 2.24 | 2.24 |
| 340.77 | 3.27 | 3.27 |
| 327.84 | 2.81 | 2.81 |
| 347.40 | 2.02 | 2.02 |
| 408.29 | 4.63 | 4.63 |
| 364.45 | 4.34 | 4.34 |
| 339.81 | 1.93 | 1.93 |
| 324.45 | 4.07 | 4.07 |
| 309.82 | 3.85 | 3.85 |
| 319.41 | 1.63 | 1.63 |
| 322.82 | 2.65 | 2.65 |
| 360.35 | 1.25 | 1.25 |
| 292.39 | 5.22 | 5.22 |
| 335.41 | 1.71 | 1.71 |
| 345.38 | 1.64 | 1.64 |
| 246.38 | 3.32 | 3.32 |
| 337.84 | 2.73 | 2.73 |
| 388.85 | 3.90 | 3.90 |
| 323.81 | 2.42 | 2.42 |
| 331.40 | 2.57 | 2.57 |
| 430.33 | 4.38 | 4.38 |
| 406.48 | 3.13 | 3.13 |
| 347.42 | 1.80 | 1.80 |
| 368.43 | 1.55 | 1.55 |
| 316.45 | 3.63 | 3.63 |
| 333.36 | 3.22 | 3.22 |
| 339.87 | 2.64 | 2.64 |
| 349.77 | 3.74 | 3.74 |
| 341.39 | 3.13 | 3.13 |
| 391.86 | 5.20 | 5.20 |
| 359.38 | 3.45 | 3.45 |
| 316.37 | 3.90 | 3.90 |
| 366.45 | 2.93 | 2.93 |
| 420.92 | 4.52 | 4.52 |
| 319.41 | 2.01 | 2.01 |
| 311.84 | 2.78 | 2.78 |
| 360.47 | 2.09 | 2.09 |
| 340.36 | 3.67 | 3.67 |
| 515.11 | 5.93 | 5.93 |
| 363.85 | 4.01 | 4.01 |
| 253.33 | 3.31 | 3.31 |
| 345.38 | 1.35 | 1.35 |
| 335.36 | 3.32 | 3.32 |
| 351.48 | 2.09 | 2.09 |
| 285.33 | 3.16 | 3.16 |
| 329.38 | 1.65 | 1.65 |
| 293.32 | 2.30 | 2.30 |
| 363.24 | 4.08 | 4.08 |
| 223.67 | 1.54 | 1.54 |
| 400.36 | 4.24 | 4.24 |
| 347.75 | 3.87 | 3.87 |
| 329.38 | 2.77 | 2.77 |
| 282.41 | 4.63 | 4.63 |
| 333.84 | 3.29 | 3.29 |
| 339.33 | 3.15 | 3.15 |
| 364.47 | 3.82 | 3.82 |
| 411.31 | 2.50 | 2.50 |
| 371.46 | 3.26 | 3.26 |
| 323.81 | 2.42 | 2.42 |
| 248.76 | 2.62 | 2.62 |
| 307.35 | 2.61 | 2.61 |
| 271.35 | 3.43 | 3.43 |
| 315.83 | 3.99 | 3.99 |
| 333.48 | 4.02 | 4.02 |
| 371.80 | 3.98 | 3.98 |
| 347.83 | 2.60 | 2.60 |
| 282.37 | 3.84 | 3.84 |
| 352.42 | 2.62 | 2.62 |
| 517.63 | 3.13 | 3.13 |
| 433.44 | 1.39 | 1.39 |
| 378.39 | 4.63 | 4.63 |
| 363.83 | 1.72 | 1.72 |
| 303.34 | 1.54 | 1.54 |
| 253.31 | 2.97 | 2.97 |
| 416.46 | 2.72 | 2.72 |
| 355.42 | 3.44 | 3.44 |
| 291.46 | 3.83 | 3.83 |
| 284.18 | 3.02 | 3.02 |
| 321.38 | 1.40 | 1.40 |
| 348.40 | 2.75 | 2.75 |
| 377.40 | 3.64 | 3.64 |
| 398.29 | 2.35 | 2.35 |
| 323.81 | 2.42 | 2.42 |
| 365.91 | 3.59 | 3.59 |
| 430.33 | 4.38 | 4.38 |
| 492.15 | 6.80 | 6.80 |
| 210.24 | 2.06 | 2.06 |
| 340.24 | 3.62 | 3.62 |
| 416.84 | 4.38 | 4.38 |
| 329.40 | 3.36 | 3.36 |
| 322.43 | 2.93 | 2.93 |
| 557.59 | 4.21 | 4.21 |
| 505.56 | 3.41 | 3.41 |
| 523.53 | 2.71 | 2.71 |
| 557.59 | 4.21 | 4.21 |
| 253.33 | 1.22 | 1.22 |
| 317.80 | 3.79 | 3.79 |
| 416.31 | 3.90 | 3.90 |
| 355.78 | 3.58 | 3.58 |
| 250.75 | 3.62 | 3.62 |
| 398.31 | 3.69 | 3.69 |
| 310.44 | 4.86 | 4.86 |
| 357.39 | 2.90 | 2.90 |
| 223.33 | 3.25 | 3.25 |
| 300.36 | 3.10 | 3.10 |
| 425.83 | 3.34 | 3.34 |
| 314.32 | 3.97 | 3.97 |
| 323.46 | 4.41 | 4.41 |
| 279.43 | 2.73 | 2.73 |
| 375.48 | 3.59 | 3.59 |
| 315.39 | 2.90 | 2.90 |
| 280.40 | 1.67 | 1.67 |
| 408.48 | 3.56 | 3.56 |
| 404.39 | 1.76 | 1.76 |
| 295.41 | 2.39 | 2.39 |
| 329.43 | 2.53 | 2.53 |
| 237.35 | 3.19 | 3.19 |
| 300.75 | 3.46 | 3.46 |
| 405.50 | 4.01 | 4.01 |
| 546.81 | 5.03 | 5.03 |
| 472.61 | 5.27 | 5.27 |
| 360.46 | 2.40 | 2.40 |
| 480.66 | 5.28 | 5.28 |
| 491.60 | 3.92 | 3.92 |
| 352.80 | 1.53 | 1.53 |
| 331.40 | 3.40 | 3.40 |
| 285.37 | 3.11 | 3.11 |
| 377.19 | 2.96 | 2.96 |
| 396.52 | ||
| 367.07 | 2.35 | 2.35 |
| 359.21 | 2.63 | 2.63 |
| 447.46 | 1.73 | 1.73 |