Basic Information
ID: ALA3215092
Type: Binding
Description: PubChem BioAssay. Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215092
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 252.32 | 2.74 | 2.74 |
| 286.24 | 2.28 | 2.28 |
| 300.22 | 1.28 | 1.28 |
| 297.27 | 2.30 | 2.30 |
| 318.24 | 1.69 | 1.69 |
| 360.32 | 1.76 | 1.76 |
| 418.28 | 3.92 | 3.92 |
| 197.19 | 0.05 | 0.05 |
| 448.38 | 0.49 | 0.49 |
| 220.18 | 0.20 | 0.20 |
| 174.16 | 0.15 | 0.15 |
| 287.31 | 1.94 | 1.94 |
| 316.26 | 2.29 | 2.29 |
| 316.26 | 2.29 | 2.29 |
| 258.23 | 2.32 | 2.32 |
| 397.42 | 1.89 | 1.89 |
| 481.60 | 5.29 | 5.29 |
| 302.24 | 1.99 | 1.99 |
| 306.28 | 3.85 | 3.85 |
| 309.37 | 2.51 | 2.51 |
| 453.46 | -0.54 | -0.54 |
| 319.86 | 2.50 | 2.50 |
| 348.31 | 2.69 | 2.69 |
| 324.41 | 4.54 | 4.54 |
| 538.46 | 5.13 | 5.13 |
| 624.59 | -1.02 | -1.02 |
| 464.38 | 0.19 | 0.19 |
| 304.25 | 1.19 | 1.19 |
| 286.28 | 2.82 | 2.82 |
| 360.32 | 2.60 | 2.60 |
| 281.27 | 1.87 | 1.87 |
| 320.25 | 1.99 | 1.99 |
| 437.19 | 3.21 | 3.21 |
| 315.35 | 3.54 | 3.54 |
| 422.49 | 2.28 | 2.28 |
| 448.38 | -0.20 | -0.20 |
| 325.32 | 2.12 | 2.12 |
| 351.41 | 1.45 | 1.45 |
| 497.58 | 5.80 | 5.80 |
| 418.45 | 2.91 | 2.91 |
| 364.40 | 3.52 | 3.52 |
| 472.50 | 3.33 | 3.33 |
| 372.43 | 3.09 | 3.09 |
| 354.31 | 2.76 | 2.76 |
| 255.28 | 1.45 | 1.45 |
| 340.21 | 3.04 | 3.04 |
| 260.25 | 1.47 | 1.47 |
| 442.57 | 3.50 | 3.50 |
| 282.25 | 2.75 | 2.75 |
| 422.34 | -0.72 | -0.72 |
| 434.41 | 1.51 | 1.51 |
| 502.60 | 5.76 | 5.76 |
| 337.16 | 3.47 | 3.47 |
| 194.22 | 1.21 | 1.21 |
| 376.41 | 0.23 | 0.23 |
| 407.81 | 3.93 | 3.93 |
| 393.42 | 4.38 | 4.38 |
| 300.31 | 3.12 | 3.12 |
| 338.39 | 3.65 | 3.65 |
| 410.47 | 2.12 | 2.12 |
| 542.50 | 3.86 | 3.86 |
| 862.75 | -1.10 | -1.10 |
| 326.38 | 3.93 | 3.93 |
| 396.45 | 1.73 | 1.73 |
| 263.30 | 3.21 | 3.21 |
| 322.32 | 3.34 | 3.34 |
| 353.36 | 2.90 | 2.90 |
| 476.55 | 5.02 | 5.02 |
| 610.52 | -2.42 | -2.42 |
| 356.38 | 3.93 | 3.93 |
| 493.94 | 0.03 | 0.03 |
| 316.41 | 3.73 | 3.73 |
| 428.47 | 2.30 | 2.30 |
| 493.50 | 3.54 | 3.54 |
| 357.42 | 2.78 | 2.78 |
| 208.17 | 0.25 | 0.25 |
| 356.37 | -0.72 | -0.72 |
| 305.38 | 4.58 | 4.58 |
| 425.47 | 2.83 | 2.83 |
| 225.25 | 2.68 | 2.68 |
| 363.37 | 3.26 | 3.26 |
| 313.34 | 1.10 | 1.10 |
| 365.42 | 2.16 | 2.16 |
| 372.43 | 2.64 | 2.64 |
| 594.52 | -1.39 | -1.39 |
| 232.26 | 3.25 | 3.25 |
| 407.81 | 3.93 | 3.93 |
| 376.75 | 3.52 | 3.52 |
| 420.45 | 4.33 | 4.33 |
| 245.27 | 1.15 | 1.15 |
| 296.28 | 2.25 | 2.25 |
| 348.36 | 1.22 | 1.22 |
| 310.38 | 4.23 | 4.23 |
| 373.41 | 2.70 | 2.70 |
| 231.25 | 2.51 | 2.51 |
| 321.35 | 2.16 | 2.16 |
| 335.39 | 4.51 | 4.51 |
| 324.41 | 4.54 | 4.54 |
| 324.41 | 3.88 | 3.88 |
| 258.23 | 2.42 | 2.42 |
| 296.35 | 3.92 | 3.92 |
| 264.20 | 0.48 | 0.48 |
| 485.50 | 2.94 | 2.94 |
| 410.47 | 1.95 | 1.95 |
| 305.38 | 4.58 | 4.58 |
| 448.38 | -0.20 | -0.20 |
| 378.46 | 3.07 | 3.07 |
| 314.32 | 1.81 | 1.81 |
| 429.48 | 3.41 | 3.41 |
| 477.50 | 4.43 | 4.43 |
| 448.49 | 5.41 | 5.41 |
| 313.33 | 3.78 | 3.78 |
| 267.12 | ||
| 342.38 | 2.51 | 2.51 |
| 310.31 | 2.41 | 2.41 |
| 331.33 | 3.19 | 3.19 |
| 364.43 | 2.77 | 2.77 |
| 329.40 | 3.95 | 3.95 |
| 474.49 | 4.20 | 4.20 |
| 480.47 | 1.57 | 1.57 |
| 438.46 | 3.30 | 3.30 |
| 191.19 | 1.50 | 1.50 |
| 353.38 | 1.96 | 1.96 |
| 293.37 | 3.69 | 3.69 |
| 421.41 | 4.70 | 4.70 |
| 396.45 | 1.73 | 1.73 |
| 286.24 | 2.36 | 2.36 |
| 231.25 | 1.93 | 1.93 |
| 285.25 | 2.02 | 2.02 |
| 296.39 | -1.11 | -1.11 |
| 417.47 | 3.33 | 3.33 |
| 416.48 | 3.60 | 3.60 |
| 496.90 | -1.24 | -1.24 |
| 478.89 | -1.69 | -1.69 |
| 273.36 | 3.45 | 3.45 |
| 387.43 | 3.00 | 3.00 |
| 491.43 | 3.30 | 3.30 |
| 312.35 | 3.62 | 3.62 |
| 405.82 | 3.94 | 3.94 |
| 418.45 | 2.91 | 2.91 |
| 373.37 | 3.27 | 3.27 |
| 354.32 | 0.95 | 0.95 |
| 257.29 | 2.43 | 2.43 |
| 365.37 | 4.05 | 4.05 |
| 316.74 | 3.83 | 3.83 |
| 385.47 | 3.73 | 3.73 |
| 368.42 | 2.91 | 2.91 |
| 255.27 | 3.13 | 3.13 |
| 214.18 | 1.79 | 1.79 |
| 460.44 | -1.24 | -1.24 |
| 461.54 | 5.13 | 5.13 |
| 421.36 | 1.70 | 1.70 |
| 464.38 | 0.19 | 0.19 |
| 316.34 | 2.50 | 2.50 |
| 432.38 | 0.09 | 0.09 |
| 278.17 | 0.72 | 0.72 |
| 221.26 | 4.00 | 4.00 |
| 234.28 | 2.07 | 2.07 |
| 344.73 | 3.12 | 3.12 |
| 477.74 | 0.71 | 0.71 |
| 259.34 | 1.29 | 1.29 |
| 308.36 | 2.66 | 2.66 |
| 359.36 | 4.40 | 4.40 |
| 389.24 | 0.54 | 0.54 |
| 359.36 | 4.40 | 4.40 |
| 309.32 | 2.51 | 2.51 |
| 311.39 | 2.76 | 2.76 |
| 191.14 | 0.45 | 0.45 |
| 256.33 | 2.83 | 2.83 |
| 404.46 | 5.06 | 5.06 |
| 209.24 | 0.93 | 0.93 |
| 250.09 | 0.30 | 0.30 |
| 296.20 | 1.98 | 1.98 |
| 415.45 | 3.84 | 3.84 |
| 414.37 | 4.53 | 4.53 |
| 238.29 | 2.34 | 2.34 |
| 523.53 | 2.71 | 2.71 |
| 323.29 | 2.82 | 2.82 |
| 322.27 | 2.28 | 2.28 |
| 316.27 | 1.04 | 1.04 |
| 315.35 | 3.54 | 3.54 |
| 365.38 | 4.03 | 4.03 |
| 416.48 | 4.53 | 4.53 |
| 240.26 | 3.70 | 3.70 |
| 400.91 | 3.29 | 3.29 |
| 308.34 | 4.25 | 4.25 |
| 286.70 | 0.12 | 0.12 |
| 360.35 | 3.62 | 3.62 |
| 267.31 | 1.86 | 1.86 |
| 245.31 | 0.98 | 0.98 |
| 438.49 | 3.82 | 3.82 |
| 402.52 | 3.74 | 3.74 |
| 291.29 | 2.68 | 2.68 |
| 332.36 | 3.67 | 3.67 |
| 516.46 | 1.03 | 1.03 |
| 185.19 | 1.99 | 1.99 |
| 272.26 | 1.96 | 1.96 |
| 368.33 | 0.80 | 0.80 |
| 406.24 | 3.65 | 3.65 |
| 471.47 | -0.54 | -0.54 |
| 333.26 | 0.78 | 0.78 |
| 343.36 | 2.48 | 2.48 |
| 375.41 | 2.36 | 2.36 |
| 318.38 | 4.06 | 4.06 |
| 427.37 | 1.73 | 1.73 |
| 222.15 | 0.47 | 0.47 |
| 331.28 | 1.87 | 1.87 |
| 265.27 | 3.15 | 3.15 |
| 345.31 | 2.39 | 2.39 |
| 413.39 | 4.09 | 4.09 |
| 478.89 | -0.44 | -0.44 |
| 325.35 | 2.55 | 2.55 |
| 376.46 | 3.00 | 3.00 |
| 257.29 | 1.98 | 1.98 |
| 273.25 | 0.96 | 0.96 |
| 358.31 | 0.11 | 0.11 |
| 354.37 | 2.25 | 2.25 |
| 332.34 | 2.33 | 2.33 |
| 279.32 | 1.39 | 1.39 |
| 449.49 | 0.91 | 0.91 |
| 410.48 | 1.37 | 1.37 |
| 248.33 | 2.69 | 2.69 |
| 264.28 | 3.40 | 3.40 |
| 384.44 | 1.47 | 1.47 |
| 494.52 | 3.04 | 3.04 |
| 423.86 | 4.16 | 4.16 |
| 261.32 | 3.49 | 3.49 |
| 396.38 | 3.61 | 3.61 |
| 288.33 | 1.81 | 1.81 |
| 304.33 | 1.52 | 1.52 |
| 293.35 | 1.78 | 1.78 |
| 288.33 | 1.81 | 1.81 |
| 298.34 | 2.69 | 2.69 |
| 280.67 | 1.69 | 1.69 |
| 378.41 | 0.79 | 0.79 |
| 311.30 | 1.70 | 1.70 |
| 286.32 | 2.97 | 2.97 |
| 282.26 | 1.73 | 1.73 |