Basic Information
ID: ALA3215116
Type: Binding
Description: PubChem BioAssay. Counterscreen for activators of kallikrein-7 (K7) zymogen: Fluorescence intensity-based biochemical high throughput dose reponse assay for activators that optically interfere with measurement of EDANS-DABCYL fluorescence. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215116
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 254.33 | 2.03 | 2.03 |
| 375.47 | 3.69 | 3.69 |
| 298.29 | 3.18 | 3.18 |
| 462.98 | 5.25 | 5.25 |
| 442.49 | 2.61 | 2.61 |
| 502.58 | 2.01 | 2.01 |
| 341.37 | 2.32 | 2.32 |
| 412.87 | 5.61 | 5.61 |
| 329.35 | 1.86 | 1.86 |
| 364.40 | 3.52 | 3.52 |
| 399.48 | 2.19 | 2.19 |
| 345.35 | 2.17 | 2.17 |
| 326.40 | 4.49 | 4.49 |
| 330.41 | 2.43 | 2.43 |
| 407.47 | 2.15 | 2.15 |
| 328.38 | 3.95 | 3.95 |
| 319.39 | 1.25 | 1.25 |
| 310.36 | 3.17 | 3.17 |
| 407.47 | 1.98 | 1.98 |
| 341.44 | 3.03 | 3.03 |
| 244.19 | 1.61 | 1.61 |
| 532.59 | 4.10 | 4.10 |
| 416.49 | 2.41 | 2.41 |
| 345.40 | 3.50 | 3.50 |
| 469.56 | 3.89 | 3.89 |
| 373.32 | 1.39 | 1.39 |
| 414.30 | 4.83 | 4.83 |
| 335.14 | 1.02 | 1.02 |
| 296.33 | 1.98 | 1.98 |
| 317.35 | 2.50 | 2.50 |
| 315.40 | 2.75 | 2.75 |
| 399.43 | 1.61 | 1.61 |
| 282.30 | 2.64 | 2.64 |
| 423.47 | 3.95 | 3.95 |
| 330.43 | 3.69 | 3.69 |
| 397.23 | 4.31 | 4.31 |
| 350.42 | 3.95 | 3.95 |
| 359.42 | 2.51 | 2.51 |
| 367.43 | 3.95 | 3.95 |
| 392.43 | 5.48 | 5.48 |
| 369.42 | 4.14 | 4.14 |
| 316.40 | 3.30 | 3.30 |
| 318.37 | 3.30 | 3.30 |
| 367.47 | 2.71 | 2.71 |
| 363.46 | 4.54 | 4.54 |
| 302.34 | 3.47 | 3.47 |
| 363.44 | 2.44 | 2.44 |
| 304.35 | 4.05 | 4.05 |
| 481.60 | 2.26 | 2.26 |
| 367.45 | 2.83 | 2.83 |
| 324.33 | 3.40 | 3.40 |
| 393.42 | 3.14 | 3.14 |
| 294.36 | 2.85 | 2.85 |
| 355.42 | 2.94 | 2.94 |
| 356.38 | 3.97 | 3.97 |
| 387.39 | 3.40 | 3.40 |
| 337.38 | 3.00 | 3.00 |
| 368.39 | 5.21 | 5.21 |
| 278.23 | 3.82 | 3.82 |
| 421.38 | 2.75 | 2.75 |
| 351.41 | 2.95 | 2.95 |
| 378.47 | 3.45 | 3.45 |
| 428.33 | 5.22 | 5.22 |
| 283.40 | 3.78 | 3.78 |
| 274.11 | 1.07 | 1.07 |
| 365.24 | 2.53 | 2.53 |
| 416.27 | 3.76 | 3.76 |
| 321.43 | 3.29 | 3.29 |
| 338.41 | 2.77 | 2.77 |
| 343.41 | 2.02 | 2.02 |
| 193.21 | 2.36 | 2.36 |
| 332.33 | 4.01 | 4.01 |
| 310.25 | 3.35 | 3.35 |
| 277.30 | 1.82 | 1.82 |
| 297.38 | 3.34 | 3.34 |
| 328.42 | 4.31 | 4.31 |
| 366.44 | 4.19 | 4.19 |
| 270.31 | 3.05 | 3.05 |
| 378.47 | 3.38 | 3.38 |
| 399.44 | 3.77 | 3.77 |
| 319.37 | 3.05 | 3.05 |
| 465.50 | 3.40 | 3.40 |
| 257.12 | 3.12 | 3.12 |
| 358.46 | 3.18 | 3.18 |
| 427.51 | 1.06 | 1.06 |
| 437.50 | 2.05 | 2.05 |
| 296.35 | 3.89 | 3.89 |
| 319.34 | 3.99 | 3.99 |
| 448.98 | 6.21 | 6.21 |
| 346.79 | 0.38 | 0.38 |
| 381.41 | 3.42 | 3.42 |
| 382.49 | 2.68 | 2.68 |
| 353.30 | 2.63 | 2.63 |
| 401.46 | 3.15 | 3.15 |
| 284.36 | 3.26 | 3.26 |
| 274.68 | 3.79 | 3.79 |
| 340.43 | 1.95 | 1.95 |
| 341.44 | 3.36 | 3.36 |
| 405.48 | 3.32 | 3.32 |
| 360.81 | 1.04 | 1.04 |
| 293.16 | 3.70 | 3.70 |
| 440.54 | 4.01 | 4.01 |
| 346.46 | 4.93 | 4.93 |
| 333.44 | 3.15 | 3.15 |
| 401.40 | 2.82 | 2.82 |
| 427.50 | 5.61 | 5.61 |
| 369.45 | 2.51 | 2.51 |
| 408.45 | 3.30 | 3.30 |
| 343.21 | 3.22 | 3.22 |
| 414.49 | 2.36 | 2.36 |
| 379.46 | 4.55 | 4.55 |
| 384.86 | 3.57 | 3.57 |
| 261.32 | 2.44 | 2.44 |
| 336.39 | 3.53 | 3.53 |
| 374.44 | 3.98 | 3.98 |
| 368.39 | 5.13 | 5.13 |
| 314.30 | 3.20 | 3.20 |
| 363.46 | 4.93 | 4.93 |
| 429.52 | 1.58 | 1.58 |
| 329.31 | 1.74 | 1.74 |
| 236.28 | 2.71 | 2.71 |
| 309.37 | 2.64 | 2.64 |
| 388.54 | 2.77 | 2.77 |
| 322.16 | 2.37 | 2.37 |
| 416.89 | 4.68 | 4.68 |
| 377.42 | 1.73 | 1.73 |
| 468.56 | 0.93 | 0.93 |
| 457.48 | 2.33 | 2.33 |
| 427.50 | 4.47 | 4.47 |
| 402.54 | 4.55 | 4.55 |
| 377.45 | 1.13 | 1.13 |
| 316.40 | 3.30 | 3.30 |
| 325.42 | 4.47 | 4.47 |
| 299.33 | 4.04 | 4.04 |
| 463.91 | 2.83 | 2.83 |
| 263.30 | 3.19 | 3.19 |
| 465.51 | 4.52 | 4.52 |
| 352.39 | 3.52 | 3.52 |
| 230.31 | 3.02 | 3.02 |
| 445.51 | 3.51 | 3.51 |
| 448.55 | 3.96 | 3.96 |
| 296.33 | 2.64 | 2.64 |
| 295.32 | 4.04 | 4.04 |
| 528.58 | 4.45 | 4.45 |
| 364.45 | 3.06 | 3.06 |
| 386.57 | 4.66 | 4.66 |
| 333.30 | 3.67 | 3.67 |
| 303.16 | 3.30 | 3.30 |
| 354.41 | 2.85 | 2.85 |
| 428.50 | 2.06 | 2.06 |
| 369.43 | 1.55 | 1.55 |
| 392.41 | 2.40 | 2.40 |
| 383.35 | 4.57 | 4.57 |
| 357.34 | 2.29 | 2.29 |
| 257.32 | 3.25 | 3.25 |
| 385.47 | 4.44 | 4.44 |
| 324.43 | 3.86 | 3.86 |
| 293.37 | 4.05 | 4.05 |
| 315.38 | 2.04 | 2.04 |
| 324.34 | 3.99 | 3.99 |
| 423.40 | 2.46 | 2.46 |
| 279.34 | 2.40 | 2.40 |
| 390.44 | 2.11 | 2.11 |
| 321.31 | 3.43 | 3.43 |
| 293.33 | 3.10 | 3.10 |
| 401.41 | 2.86 | 2.86 |
| 311.34 | 2.65 | 2.65 |
| 309.33 | 3.41 | 3.41 |
| 425.47 | 2.76 | 2.76 |
| 361.45 | 2.56 | 2.56 |
| 248.71 | 3.03 | 3.03 |
| 238.31 | 2.77 | 2.77 |
| 354.36 | 3.40 | 3.40 |
| 379.37 | 1.60 | 1.60 |
| 386.43 | 1.82 | 1.82 |
| 350.42 | 4.44 | 4.44 |
| 324.29 | 3.03 | 3.03 |
| 305.34 | 2.74 | 2.74 |
| 538.59 | 4.51 | 4.51 |
| 357.39 | 2.91 | 2.91 |
| 255.30 | 0.36 | 0.36 |
| 317.17 | 2.35 | 2.35 |
| 409.42 | 4.78 | 4.78 |
| 331.32 | 1.27 | 1.27 |
| 385.42 | 3.29 | 3.29 |
| 314.34 | 3.86 | 3.86 |
| 379.34 | 2.40 | 2.40 |
| 369.46 | 1.27 | 1.27 |
| 439.49 | 2.87 | 2.87 |
| 270.36 | 3.26 | 3.26 |
| 435.44 | 3.21 | 3.21 |
| 259.31 | 4.45 | 4.45 |
| 230.27 | 1.78 | 1.78 |
| 341.44 | 3.31 | 3.31 |
| 691.87 | 5.13 | 5.13 |
| 357.40 | 1.67 | 1.67 |
| 318.38 | 3.80 | 3.80 |
| 460.53 | 2.68 | 2.68 |
| 439.51 | 2.65 | 2.65 |
| 368.50 | 4.32 | 4.32 |
| 449.47 | 3.52 | 3.52 |
| 357.40 | 2.00 | 2.00 |
| 375.55 | 4.59 | 4.59 |
| 398.23 | 3.18 | 3.18 |
| 462.33 | 3.48 | 3.48 |
| 337.76 | 1.99 | 1.99 |
| 453.56 | 2.68 | 2.68 |
| 326.36 | 0.97 | 0.97 |
| 370.48 | 3.34 | 3.34 |
| 237.31 | 3.07 | 3.07 |
| 251.28 | 3.70 | 3.70 |
| 214.27 | 2.28 | 2.28 |
| 302.37 | 1.96 | 1.96 |
| 486.40 | 4.44 | 4.44 |
| 513.54 | -0.25 | -0.25 |
| 442.50 | 3.35 | 3.35 |
| 238.29 | 2.84 | 2.84 |
| 288.35 | 4.04 | 4.04 |
| 238.29 | 2.84 | 2.84 |
| 478.51 | 2.90 | 2.90 |
| 224.26 | 2.54 | 2.54 |
| 372.45 | 4.61 | 4.61 |
| 602.69 | 6.68 | 6.68 |
| 338.41 | 2.73 | 2.73 |
| 438.57 | 3.34 | 3.34 |
| 215.26 | 2.19 | 2.19 |
| 289.34 | 1.79 | 1.79 |
| 246.22 | 2.26 | 2.26 |
| 288.33 | 1.77 | 1.77 |
| 560.65 | 6.98 | 6.98 |
| 299.40 | 3.67 | 3.67 |
| 240.31 | 2.38 | 2.38 |
| 367.36 | 2.66 | 2.66 |
| 229.67 | 3.05 | 3.05 |
| 398.43 | 5.73 | 5.73 |
| 350.42 | 3.24 | 3.24 |
| 348.83 | 1.92 | 1.92 |
| 314.35 | 3.65 | 3.65 |
| 398.47 | 4.62 | 4.62 |
| 407.47 | 1.84 | 1.84 |
| 498.54 | 3.15 | 3.15 |
| 374.40 | 4.37 | 4.37 |
| 352.39 | 2.73 | 2.73 |
| 323.42 | 1.20 | 1.20 |
| 402.84 | 3.09 | 3.09 |
| 568.70 | 3.02 | 3.02 |
| 252.28 | 2.32 | 2.32 |
| 401.45 | 4.43 | 4.43 |