Basic Information
ID: ALA3215131
Type: Functional
Description: PubChem BioAssay. Counterscreen for inhibitors of cell surface Prion Protein (PrPc): Luminescence-based cell-based high throughput dose response assay to identify compounds that are cytotoxic to LD9 cells. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215131
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.36 | 1.96 | 1.96 |
| 449.80 | 5.40 | 5.40 |
| 334.19 | 4.42 | 4.42 |
| 334.60 | 4.79 | 4.79 |
| 289.31 | 2.90 | 2.90 |
| 430.56 | 3.39 | 3.39 |
| 416.51 | 3.95 | 3.95 |
| 346.45 | 2.88 | 2.88 |
| 284.28 | 1.56 | 1.56 |
| 301.42 | 2.98 | 2.98 |
| 276.36 | 2.85 | 2.85 |
| 258.35 | 2.97 | 2.97 |
| 294.40 | 3.02 | 3.02 |
| 371.44 | 4.43 | 4.43 |
| 316.98 | 3.77 | 3.77 |
| 433.41 | 4.33 | 4.33 |
| 277.43 | 3.94 | 3.94 |
| 423.54 | 3.49 | 3.49 |
| 352.46 | 4.75 | 4.75 |
| 351.16 | 3.78 | 3.78 |
| 369.45 | 3.25 | 3.25 |
| 253.71 | 3.06 | 3.06 |
| 316.41 | 4.16 | 4.16 |
| 449.35 | 4.98 | 4.98 |
| 272.37 | 3.43 | 3.43 |
| 359.48 | 3.64 | 3.64 |
| 492.35 | 5.15 | 5.15 |
| 342.42 | 2.70 | 2.70 |
| 298.37 | 3.12 | 3.12 |
| 358.49 | 4.25 | 4.25 |
| 337.16 | 3.47 | 3.47 |
| 389.46 | 1.00 | 1.00 |
| 290.78 | 3.37 | 3.37 |
| 380.52 | 4.55 | 4.55 |
| 310.38 | 3.56 | 3.56 |
| 394.29 | 3.52 | 3.52 |
| 272.37 | 3.36 | 3.36 |
| 233.29 | 2.80 | 2.80 |
| 504.39 | 2.29 | 2.29 |
| 340.40 | 3.47 | 3.47 |
| 474.56 | 2.39 | 2.39 |
| 314.82 | 2.15 | 2.15 |
| 384.53 | 4.26 | 4.26 |
| 350.38 | 2.04 | 2.04 |
| 342.42 | 3.61 | 3.61 |
| 346.39 | 3.73 | 3.73 |
| 497.35 | 5.08 | 5.08 |
| 319.36 | 4.93 | 4.93 |
| 425.54 | 2.94 | 2.94 |
| 298.32 | 3.88 | 3.88 |
| 421.29 | 3.28 | 3.28 |
| 304.42 | 3.58 | 3.58 |
| 296.43 | 4.70 | 4.70 |
| 327.39 | 0.36 | 0.36 |
| 432.32 | 4.52 | 4.52 |
| 316.36 | 3.26 | 3.26 |
| 290.39 | 3.24 | 3.24 |
| 479.38 | 5.08 | 5.08 |
| 338.43 | 4.36 | 4.36 |
| 367.24 | 3.76 | 3.76 |
| 242.69 | 2.69 | 2.69 |
| 342.40 | 4.09 | 4.09 |
| 314.41 | 4.45 | 4.45 |
| 325.20 | 4.07 | 4.07 |
| 280.37 | 2.75 | 2.75 |
| 327.39 | 4.38 | 4.38 |
| 475.35 | 0.95 | 0.95 |
| 450.47 | 3.48 | 3.48 |
| 359.86 | 4.73 | 4.73 |
| 406.75 | 4.57 | 4.57 |
| 386.52 | 3.40 | 3.40 |
| 338.43 | 4.36 | 4.36 |
| 219.26 | 2.41 | 2.41 |
| 297.38 | 3.70 | 3.70 |
| 324.41 | 3.95 | 3.95 |
| 429.57 | 6.11 | 6.11 |
| 296.35 | 4.14 | 4.14 |
| 341.37 | 2.85 | 2.85 |
| 376.28 | 5.29 | 5.29 |
| 547.62 | 3.66 | 3.66 |
| 247.10 | 3.48 | 3.48 |
| 290.39 | 3.41 | 3.41 |
| 432.45 | 4.71 | 4.71 |
| 316.41 | 3.62 | 3.62 |
| 373.49 | 3.79 | 3.79 |
| 327.02 | 4.25 | 4.25 |
| 342.19 | 4.67 | 4.67 |
| 231.28 | 2.41 | 2.41 |
| 427.48 | 4.70 | 4.70 |
| 364.45 | 3.83 | 3.83 |
| 241.70 | 2.66 | 2.66 |
| 249.32 | 2.50 | 2.50 |
| 357.21 | 4.01 | 4.01 |
| 396.52 | 4.78 | 4.78 |
| 261.35 | 3.42 | 3.42 |
| 331.01 | 4.08 | 4.08 |
| 319.43 | 3.99 | 3.99 |
| 317.46 | 3.59 | 3.59 |
| 344.47 | 3.94 | 3.94 |
| 411.53 | 3.20 | 3.20 |
| 380.47 | 3.05 | 3.05 |
| 396.50 | 4.77 | 4.77 |
| 446.48 | 5.10 | 5.10 |
| 379.25 | 3.17 | 3.17 |
| 357.21 | 4.01 | 4.01 |
| 386.82 | 3.70 | 3.70 |
| 349.40 | 1.33 | 1.33 |
| 515.57 | 3.25 | 3.25 |
| 328.37 | 3.70 | 3.70 |
| 423.31 | 4.91 | 4.91 |
| 340.47 | 3.24 | 3.24 |
| 372.49 | 3.01 | 3.01 |
| 286.79 | 4.16 | 4.16 |
| 405.50 | 3.24 | 3.24 |
| 410.50 | 3.32 | 3.32 |
| 392.48 | 3.83 | 3.83 |
| 247.32 | 3.11 | 3.11 |
| 296.42 | 3.35 | 3.35 |
| 335.27 | 4.87 | 4.87 |
| 467.99 | 2.85 | 2.85 |
| 268.11 | 3.19 | 3.19 |
| 338.43 | 4.34 | 4.34 |
| 379.81 | 3.71 | 3.71 |
| 352.43 | 1.81 | 1.81 |
| 396.47 | 2.75 | 2.75 |
| 392.71 | 3.01 | 3.01 |
| 276.36 | 3.02 | 3.02 |
| 423.50 | 3.21 | 3.21 |
| 201.25 | 2.35 | 2.35 |
| 338.43 | 3.88 | 3.88 |
| 302.28 | 1.32 | 1.32 |
| 234.31 | 1.85 | 1.85 |
| 309.34 | 2.14 | 2.14 |
| 486.37 | 3.76 | 3.76 |
| 394.50 | 3.48 | 3.48 |
| 268.35 | 2.21 | 2.21 |
| 270.36 | 3.03 | 3.03 |
| 327.34 | 3.75 | 3.75 |
| 421.46 | 0.71 | 0.71 |
| 366.47 | 4.79 | 4.79 |
| 383.27 | 2.99 | 2.99 |
| 491.55 | 5.14 | 5.14 |
| 274.32 | 2.86 | 2.86 |
| 334.21 | 4.27 | 4.27 |
| 430.56 | 3.40 | 3.40 |
| 299.36 | 2.63 | 2.63 |
| 445.34 | 3.99 | 3.99 |
| 444.54 | 2.38 | 2.38 |
| 266.09 | 2.81 | 2.81 |
| 366.49 | 3.99 | 3.99 |
| 324.41 | 3.49 | 3.49 |
| 332.43 | 3.52 | 3.52 |
| 283.36 | 3.23 | 3.23 |
| 456.59 | 3.84 | 3.84 |
| 288.33 | 2.57 | 2.57 |
| 429.53 | 2.55 | 2.55 |
| 192.24 | 2.33 | 2.33 |
| 361.19 | 4.74 | 4.74 |
| 367.40 | 3.52 | 3.52 |
| 389.36 | 4.34 | 4.34 |
| 272.38 | 3.26 | 3.26 |
| 255.27 | 2.80 | 2.80 |
| 426.38 | 4.60 | 4.60 |
| 332.36 | 2.89 | 2.89 |
| 474.31 | 3.85 | 3.85 |
| 328.42 | 4.03 | 4.03 |
| 398.56 | 4.82 | 4.82 |
| 248.31 | 2.51 | 2.51 |
| 300.39 | 3.12 | 3.12 |
| 267.74 | 3.15 | 3.15 |
| 247.32 | 2.89 | 2.89 |
| 371.08 | 4.15 | 4.15 |
| 302.38 | 3.54 | 3.54 |
| 354.43 | 3.86 | 3.86 |
| 233.29 | 2.80 | 2.80 |
| 323.42 | 3.08 | 3.08 |
| 327.43 | 4.80 | 4.80 |
| 410.50 | 3.14 | 3.14 |
| 332.43 | 2.09 | 2.09 |
| 367.50 | 3.96 | 3.96 |
| 469.61 | 3.64 | 3.64 |
| 429.93 | 4.08 | 4.08 |
| 367.39 | 2.75 | 2.75 |
| 352.46 | 4.26 | 4.26 |
| 386.42 | 3.02 | 3.02 |
| 443.53 | 4.72 | 4.72 |
| 355.42 | 3.00 | 3.00 |
| 252.73 | 3.07 | 3.07 |
| 377.82 | 4.64 | 4.64 |
| 337.40 | 3.02 | 3.02 |
| 395.21 | 1.99 | 1.99 |
| 511.37 | 4.11 | 4.11 |
| 383.52 | 3.17 | 3.17 |
| 402.50 | 2.61 | 2.61 |
| 328.44 | 5.37 | 5.37 |
| 267.38 | 3.54 | 3.54 |
| 386.41 | 3.85 | 3.85 |
| 458.57 | 2.69 | 2.69 |
| 390.46 | 3.02 | 3.02 |
| 457.53 | 4.74 | 4.74 |
| 480.59 | 4.60 | 4.60 |
| 315.17 | 4.07 | 4.07 |
| 291.36 | 2.46 | 2.46 |
| 400.23 | 3.45 | 3.45 |
| 342.42 | 3.78 | 3.78 |
| 485.33 | 3.05 | 3.05 |
| 423.54 | 3.78 | 3.78 |
| 353.40 | 2.77 | 2.77 |
| 231.35 | 4.12 | 4.12 |
| 361.20 | 3.92 | 3.92 |
| 370.41 | 2.63 | 2.63 |
| 475.64 | 3.50 | 3.50 |
| 295.37 | 2.87 | 2.87 |
| 350.17 | 3.70 | 3.70 |
| 394.52 | 2.55 | 2.55 |
| 380.50 | 2.25 | 2.25 |
| 396.44 | 3.42 | 3.42 |
| 476.00 | 3.63 | 3.63 |
| 381.27 | 5.56 | 5.56 |
| 457.76 | 6.03 | 6.03 |
| 353.22 | 4.95 | 4.95 |
| 441.30 | 5.51 | 5.51 |
| 355.19 | 4.53 | 4.53 |
| 371.21 | 5.09 | 5.09 |
| 382.47 | 4.39 | 4.39 |
| 471.78 | 6.33 | 6.33 |
| 287.38 | 3.57 | 3.57 |
| 367.25 | 5.26 | 5.26 |
| 407.31 | 3.91 | 3.91 |
| 407.26 | 3.85 | 3.85 |
| 280.36 | 1.96 | 1.96 |
| 488.32 | 6.23 | 6.23 |
| 307.19 | 3.73 | 3.73 |
| 286.40 | 3.75 | 3.75 |
| 401.69 | 5.91 | 5.91 |
| 432.45 | 4.71 | 4.71 |
| 406.26 | 5.37 | 5.37 |
| 300.10 | 2.59 | 2.59 |
| 385.24 | 5.40 | 5.40 |
| 613.81 | ||
| 675.55 | 7.69 | 7.69 |
| 390.67 | 4.16 | 4.16 |