Basic Information
ID: ALA3215177
Type: Functional
Description: PubChem BioAssay. PAX8: non-specific cytotoxicity Measured in Cell-Based System Using Plate Reader - 7054-05_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215177
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.33 | -0.36 | -0.36 |
| 299.31 | -1.32 | -1.32 |
| 167.20 | 0.60 | 0.60 |
| 272.30 | 4.61 | 4.61 |
| 479.62 | 3.49 | 3.49 |
| 287.16 | 4.07 | 4.07 |
| 453.29 | 3.36 | 3.36 |
| 309.28 | -2.28 | -2.28 |
| 264.33 | 3.75 | 3.75 |
| 210.19 | 1.52 | 1.52 |
| 327.43 | 5.95 | 5.95 |
| 352.91 | 3.97 | 3.97 |
| 525.09 | 4.92 | 4.92 |
| 330.29 | 1.53 | 1.53 |
| 334.42 | 4.34 | 4.34 |
| 309.33 | 1.03 | 1.03 |
| 241.08 | 2.54 | 2.54 |
| 255.10 | 2.85 | 2.85 |
| 302.28 | 1.72 | 1.72 |
| 234.25 | -0.71 | -0.71 |
| 545.08 | 4.67 | 4.67 |
| 507.57 | 4.31 | 4.31 |
| 318.43 | 3.51 | 3.51 |
| 386.48 | 4.31 | 4.31 |
| 424.33 | 5.76 | 5.76 |
| 408.72 | 5.26 | 5.26 |
| 298.37 | 3.34 | 3.34 |
| 356.81 | 4.21 | 4.21 |
| 404.35 | 4.96 | 4.96 |
| 288.26 | 2.56 | 2.56 |
| 705.66 | 5.71 | 5.71 |
| 449.38 | 5.11 | 5.11 |
| 487.00 | 2.60 | 2.60 |
| 278.29 | 2.13 | 2.13 |
| 271.28 | 1.57 | 1.57 |
| 366.45 | 3.71 | 3.71 |
| 489.62 | 3.24 | 3.24 |
| 279.78 | 3.86 | 3.86 |
| 253.37 | 5.09 | 5.09 |
| 334.80 | 2.57 | 2.57 |
| 396.38 | 3.42 | 3.42 |
| 431.90 | 3.75 | 3.75 |
| 505.10 | 4.69 | 4.69 |
| 392.01 | 1.56 | 1.56 |
| 383.84 | 3.06 | 3.06 |
| 506.57 | 6.00 | 6.00 |
| 253.77 | 3.84 | 3.84 |
| 284.34 | 3.96 | 3.96 |
| 283.28 | 2.55 | 2.55 |
| 251.76 | 3.59 | 3.59 |
| 326.78 | 4.20 | 4.20 |
| 271.28 | 1.16 | 1.16 |
| 341.28 | 3.29 | 3.29 |
| 276.32 | 2.48 | 2.48 |
| 336.28 | 2.08 | 2.08 |
| 273.76 | 3.77 | 3.77 |
| 289.36 | 2.02 | 2.02 |
| 255.28 | 1.87 | 1.87 |
| 415.92 | 3.85 | 3.85 |
| 381.41 | 3.17 | 3.17 |
| 487.00 | 2.74 | 2.74 |
| 417.87 | 3.36 | 3.36 |
| 291.78 | 3.28 | 3.28 |
| 445.93 | 4.06 | 4.06 |
| 494.98 | 3.00 | 3.00 |
| 410.45 | 1.48 | 1.48 |
| 414.51 | 3.77 | 3.77 |
| 329.27 | 1.87 | 1.87 |
| 262.31 | 3.80 | 3.80 |
| 444.90 | 3.31 | 3.31 |
| 644.77 | 4.82 | 4.82 |
| 342.90 | 2.31 | 2.31 |
| 399.41 | 2.23 | 2.23 |
| 484.60 | 4.28 | 4.28 |
| 425.36 | 5.93 | 5.93 |
| 347.33 | 3.84 | 3.84 |
| 447.39 | 5.07 | 5.07 |
| 358.78 | 3.51 | 3.51 |
| 428.96 | 4.77 | 4.77 |
| 219.26 | 3.02 | 3.02 |
| 385.45 | 4.48 | 4.48 |
| 285.30 | 1.96 | 1.96 |
| 402.62 | 4.17 | 4.17 |
| 267.29 | 2.82 | 2.82 |
| 412.51 | 3.53 | 3.53 |
| 485.31 | 6.57 | 6.57 |
| 329.98 | 2.76 | 2.76 |
| 270.31 | 3.24 | 3.24 |
| 359.81 | 3.75 | 3.75 |
| 339.80 | 2.48 | 2.48 |
| 442.97 | 4.43 | 4.43 |
| 476.34 | 4.08 | 4.08 |
| 451.59 | 4.39 | 4.39 |
| 403.89 | 3.98 | 3.98 |
| 420.34 | 4.50 | 4.50 |
| 454.58 | 4.27 | 4.27 |
| 276.30 | 2.57 | 2.57 |
| 612.78 | 5.84 | 5.84 |
| 269.34 | 3.89 | 3.89 |
| 477.41 | 5.08 | 5.08 |
| 364.79 | 2.82 | 2.82 |
| 364.37 | 3.88 | 3.88 |
| 240.65 | -0.01 | -0.01 |
| 371.19 | 3.77 | 3.77 |
| 288.30 | 4.32 | 4.32 |
| 485.64 | 5.83 | 5.83 |
| 404.91 | 3.85 | 3.85 |
| 417.47 | 2.81 | 2.81 |
| 344.44 | 3.49 | 3.49 |
| 264.26 | 1.82 | 1.82 |
| 371.42 | 4.16 | 4.16 |
| 284.34 | 3.56 | 3.56 |
| 331.80 | 3.70 | 3.70 |
| 196.21 | 2.51 | 2.51 |
| 455.39 | 5.80 | 5.80 |
| 405.41 | 5.30 | 5.30 |
| 442.95 | 5.00 | 5.00 |
| 251.29 | 1.24 | 1.24 |
| 510.43 | 4.86 | 4.86 |
| 471.56 | 6.29 | 6.29 |
| 485.58 | 5.27 | 5.27 |
| 259.74 | 3.46 | 3.46 |
| 312.87 | 2.71 | 2.71 |
| 367.67 | 4.82 | 4.82 |
| 659.63 | 6.93 | 6.93 |
| 281.83 | 4.54 | 4.54 |
| 514.48 | 3.67 | 3.67 |
| 406.44 | 3.44 | 3.44 |
| 408.89 | 3.53 | 3.53 |
| 443.48 | 5.42 | 5.42 |
| 340.81 | 4.02 | 4.02 |
| 455.53 | 5.25 | 5.25 |
| 310.38 | 2.85 | 2.85 |
| 338.36 | 3.82 | 3.82 |
| 384.55 | 3.31 | 3.31 |
| 368.35 | 2.76 | 2.76 |
| 306.67 | 3.23 | 3.23 |
| 262.27 | 2.26 | 2.26 |
| 300.31 | 3.43 | 3.43 |
| 393.48 | 4.24 | 4.24 |
| 373.37 | -0.24 | -0.24 |
| 650.86 | 7.40 | 7.40 |
| 477.74 | 0.71 | 0.71 |
| 600.73 | 4.72 | 4.72 |
| 277.71 | 2.43 | 2.43 |
| 325.37 | 1.57 | 1.57 |
| 450.62 | 6.70 | 6.70 |
| 277.28 | 2.38 | 2.38 |
| 403.55 | 6.18 | 6.18 |
| 406.48 | 0.95 | 0.95 |
| 398.42 | 1.53 | 1.53 |
| 255.23 | 1.12 | 1.12 |
| 633.56 | -0.32 | -0.32 |
| 444.53 | 6.25 | 6.25 |
| 266.26 | -1.35 | -1.35 |
| 373.41 | 4.07 | 4.07 |
| 286.70 | 0.12 | 0.12 |
| 253.06 | 1.03 | 1.03 |
| 545.46 | 6.16 | 6.16 |
| 310.31 | 2.61 | 2.61 |
| 355.78 | 3.58 | 3.58 |
| 515.60 | 3.98 | 3.98 |
| 673.83 | 3.55 | 3.55 |
| 493.62 | 4.79 | 4.79 |
| 593.57 | 4.81 | 4.81 |
| 471.59 | 6.45 | 6.45 |
| 431.88 | 3.59 | 3.59 |
| 246.35 | 3.00 | 3.00 |
| 646.13 | 6.12 | 6.12 |
| 248.29 | 3.08 | 3.08 |
| 756.70 | 6.29 | 6.29 |
| 353.44 | 3.95 | 3.95 |
| 509.61 | 4.74 | 4.74 |
| 362.47 | 2.25 | 2.25 |
| 276.30 | 3.53 | 3.53 |
| 477.60 | 4.81 | 4.81 |
| 417.52 | 3.56 | 3.56 |
| 505.58 | 4.95 | 4.95 |
| 495.51 | 4.55 | 4.55 |
| 487.63 | 4.64 | 4.64 |
| 394.39 | 2.71 | 2.71 |
| 537.62 | 4.50 | 4.50 |
| 402.83 | 2.57 | 2.57 |
| 337.38 | 3.71 | 3.71 |
| 595.59 | 2.27 | 2.27 |
| 459.63 | 3.57 | 3.57 |
| 284.27 | 2.56 | 2.56 |
| 305.38 | 4.31 | 4.31 |
| 300.36 | 3.10 | 3.10 |
| 316.81 | 3.42 | 3.42 |
| 292.30 | 2.77 | 2.77 |
| 370.25 | 4.76 | 4.76 |
| 280.78 | 2.57 | 2.57 |
| 541.50 | 0.96 | 0.96 |
| 488.55 | 4.20 | 4.20 |
| 401.50 | 2.96 | 2.96 |
| 254.32 | 3.14 | 3.14 |
| 350.38 | 3.32 | 3.32 |
| 324.28 | 3.08 | 3.08 |
| 473.59 | 5.26 | 5.26 |
| 230.22 | 1.49 | 1.49 |
| 549.59 | 4.66 | 4.66 |
| 664.70 | 4.90 | 4.90 |
| 728.81 | 7.01 | 7.01 |
| 496.63 | 5.16 | 5.16 |
| 470.61 | 4.36 | 4.36 |
| 684.80 | 7.28 | 7.28 |
| 472.59 | 4.01 | 4.01 |
| 702.79 | 7.42 | 7.42 |
| 672.29 | 6.07 | 6.07 |
| 728.35 | 5.32 | 5.32 |
| 614.67 | 5.71 | 5.71 |
| 664.82 | 6.41 | 6.41 |
| 681.90 | 5.73 | 5.73 |
| 437.47 | 5.34 | 5.34 |
| 459.57 | 3.88 | 3.88 |
| 504.58 | 2.73 | 2.73 |
| 376.45 | 4.57 | 4.57 |
| 657.83 | 5.87 | 5.87 |
| 405.45 | 4.60 | 4.60 |
| 605.78 | 5.82 | 5.82 |
| 542.70 | 3.68 | 3.68 |
| 711.83 | 6.10 | 6.10 |
| 549.69 | 3.39 | 3.39 |
| 712.81 | 6.85 | 6.85 |
| 446.57 | 3.99 | 3.99 |
| 714.83 | 7.29 | 7.29 |
| 414.51 | 3.46 | 3.46 |
| 621.70 | 6.78 | 6.78 |
| 428.53 | 2.58 | 2.58 |
| 418.49 | 1.81 | 1.81 |
| 751.35 | 7.25 | 7.25 |
| 707.33 | 5.91 | 5.91 |
| 769.28 | 7.12 | 7.12 |
| 483.59 | 4.68 | 4.68 |
| 430.55 | 4.32 | 4.32 |
| 735.90 | 4.75 | 4.75 |
| 448.58 | 3.02 | 3.02 |
| 714.83 | 7.29 | 7.29 |
| 698.78 | 6.92 | 6.92 |
| 719.85 | 7.12 | 7.12 |
| 618.68 | 5.12 | 5.12 |
| 592.20 | 4.80 | 4.80 |
| 604.79 | 3.72 | 3.72 |
| 483.57 | 4.07 | 4.07 |
| 722.33 | 5.26 | 5.26 |
| 705.84 | 6.43 | 6.43 |
| 485.63 | 5.13 | 5.13 |
| 429.52 | 4.34 | 4.34 |
| 511.69 | 3.52 | 3.52 |
| 605.68 | 5.61 | 5.61 |
| 566.72 | 3.31 | 3.31 |
| 451.49 | 5.65 | 5.65 |
| 490.67 | 4.58 | 4.58 |
| 592.67 | 3.14 | 3.14 |
| 643.89 | 5.80 | 5.80 |
| 734.84 | 6.47 | 6.47 |
| 388.44 | 3.20 | 3.20 |
| 527.97 | 6.51 | 6.51 |
| 688.55 | 7.98 | 7.98 |
| 417.48 | 4.47 | 4.47 |
| 587.78 | 7.19 | 7.19 |
| 386.45 | 2.68 | 2.68 |
| 433.60 | 3.17 | 3.17 |
| 477.56 | 5.09 | 5.09 |
| 752.35 | 5.27 | 5.27 |
| 735.87 | 6.44 | 6.44 |
| 610.80 | 4.83 | 4.83 |
| 620.73 | 4.43 | 4.43 |
| 719.87 | 6.74 | 6.74 |
| 451.49 | 5.65 | 5.65 |
| 467.61 | 4.25 | 4.25 |
| 495.62 | 4.55 | 4.55 |
| 525.49 | 6.08 | 6.08 |
| 501.63 | 4.70 | 4.70 |
| 633.76 | 3.40 | 3.40 |
| 549.69 | 3.39 | 3.39 |
| 562.73 | 3.99 | 3.99 |
| 405.45 | 4.60 | 4.60 |
| 655.83 | 5.55 | 5.55 |
| 400.48 | 3.07 | 3.07 |
| 504.58 | 2.73 | 2.73 |
| 662.73 | 5.13 | 5.13 |
| 456.51 | 4.17 | 4.17 |
| 413.50 | 4.97 | 4.97 |
| 564.68 | 3.70 | 3.70 |
| 705.84 | 6.43 | 6.43 |
| 482.58 | 4.06 | 4.06 |
| 483.57 | 4.07 | 4.07 |
| 410.52 | 4.53 | 4.53 |
| 496.59 | 4.04 | 4.04 |
| 511.52 | 5.99 | 5.99 |
| 619.12 | 4.66 | 4.66 |
| 728.81 | 7.01 | 7.01 |
| 573.74 | 5.29 | 5.29 |
| 620.60 | 5.08 | 5.08 |
| 714.86 | 5.59 | 5.59 |
| 262.32 | 3.47 | 3.47 |
| 455.46 | 5.48 | 5.48 |
| 719.87 | 6.74 | 6.74 |
| 541.55 | 6.00 | 6.00 |
| 513.61 | 4.69 | 4.69 |
| 465.60 | 4.54 | 4.54 |
| 522.62 | 3.43 | 3.43 |
| 683.81 | 6.81 | 6.81 |
| 740.32 | 5.40 | 5.40 |
| 513.61 | 4.69 | 4.69 |
| 552.62 | 3.60 | 3.60 |
| 401.49 | 4.77 | 4.77 |
| 740.32 | 5.40 | 5.40 |
| 719.87 | 6.74 | 6.74 |
| 549.69 | 3.39 | 3.39 |
| 670.68 | 7.17 | 7.17 |
| 706.73 | 6.72 | 6.72 |
| 495.62 | 4.55 | 4.55 |
| 728.35 | 5.32 | 5.32 |
| 752.35 | 5.27 | 5.27 |
| 740.28 | 7.09 | 7.09 |
| 685.69 | 7.56 | 7.56 |
| 394.49 | 3.58 | 3.58 |
| 669.79 | 6.89 | 6.89 |
| 472.49 | 3.18 | 3.18 |
| 572.66 | 4.54 | 4.54 |
| 372.49 | 4.74 | 4.74 |
| 596.19 | 4.50 | 4.50 |
| 491.18 | 5.19 | 5.19 |
| 434.47 | 3.77 | 3.77 |
| 335.64 | 3.57 | 3.57 |
| 301.30 | 2.78 | 2.78 |
| 301.20 | 2.92 | 2.92 |
| 272.30 | 2.93 | 2.93 |
| 350.38 | 3.32 | 3.32 |
| 274.35 | 2.11 | 2.11 |
| 450.46 | 3.28 | 3.28 |
| 286.29 | 2.55 | 2.55 |
| 464.54 | 2.87 | 2.87 |
| 450.51 | 2.48 | 2.48 |