Basic Information
ID: ALA3215227
Type: Functional
Description: PubChem BioAssay. SA13 PAX8: cytotoxicity OVCAR8 Measured in Cell-Based System Using Plate Reader - 7054-15_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory)
Cell type: OVCAR-8
Activity Charts
Bioactivity
Activity Types for Assay ALA3215227
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 604.79 | 3.72 | 3.72 |
| 610.18 | 5.18 | 5.18 |
| 703.68 | 7.70 | 7.70 |
| 719.28 | 6.24 | 6.24 |
| 540.69 | 3.70 | 3.70 |
| 684.80 | 7.28 | 7.28 |
| 681.63 | 6.75 | 6.75 |
| 714.83 | 7.29 | 7.29 |
| 728.81 | 7.01 | 7.01 |
| 562.73 | 3.99 | 3.99 |
| 638.59 | 5.21 | 5.21 |
| 394.49 | 3.58 | 3.58 |
| 612.82 | 6.09 | 6.09 |
| 559.71 | 3.94 | 3.94 |
| 443.55 | 3.70 | 3.70 |
| 690.76 | 7.42 | 7.42 |
| 669.79 | 6.89 | 6.89 |
| 310.40 | 2.45 | 2.45 |
| 728.81 | 7.01 | 7.01 |
| 496.63 | 5.16 | 5.16 |
| 556.87 | 4.49 | 4.49 |
| 684.80 | 7.28 | 7.28 |
| 702.79 | 7.42 | 7.42 |
| 472.59 | 4.01 | 4.01 |
| 619.71 | 4.79 | 4.79 |
| 657.92 | 6.10 | 6.10 |
| 592.69 | 4.93 | 4.93 |
| 377.49 | 2.84 | 2.84 |
| 415.54 | 4.48 | 4.48 |
| 430.52 | 4.44 | 4.44 |
| 612.82 | 6.09 | 6.09 |
| 707.94 | 4.97 | 4.97 |
| 492.64 | 3.12 | 3.12 |
| 494.61 | 3.93 | 3.93 |
| 702.79 | 7.42 | 7.42 |
| 496.61 | 4.69 | 4.69 |
| 705.84 | 6.43 | 6.43 |
| 643.89 | 5.80 | 5.80 |
| 510.53 | 3.66 | 3.66 |
| 728.35 | 5.32 | 5.32 |
| 559.73 | 4.77 | 4.77 |
| 494.61 | 3.93 | 3.93 |
| 703.68 | 7.70 | 7.70 |
| 685.79 | 6.67 | 6.67 |
| 685.69 | 7.56 | 7.56 |
| 664.82 | 6.41 | 6.41 |
| 681.90 | 5.73 | 5.73 |
| 661.80 | 5.70 | 5.70 |
| 562.73 | 3.99 | 3.99 |
| 611.74 | 5.13 | 5.13 |
| 602.68 | 4.99 | 4.99 |
| 719.87 | 6.74 | 6.74 |
| 769.28 | 7.12 | 7.12 |
| 678.34 | 6.45 | 6.45 |
| 712.81 | 6.85 | 6.85 |
| 376.45 | 4.57 | 4.57 |
| 752.83 | 6.60 | 6.60 |
| 495.62 | 4.55 | 4.55 |
| 728.81 | 7.01 | 7.01 |
| 569.58 | 5.61 | 5.61 |
| 405.45 | 4.60 | 4.60 |
| 617.55 | 6.06 | 6.06 |
| 378.47 | 1.80 | 1.80 |
| 540.06 | 4.81 | 4.81 |
| 756.77 | 5.91 | 5.91 |
| 605.68 | 5.61 | 5.61 |
| 483.59 | 4.68 | 4.68 |
| 678.80 | 6.13 | 6.13 |
| 490.67 | 4.58 | 4.58 |
| 711.83 | 6.10 | 6.10 |
| 480.59 | 3.91 | 3.91 |
| 602.68 | 4.99 | 4.99 |
| 712.81 | 6.85 | 6.85 |
| 715.93 | 5.22 | 5.22 |
| 336.41 | 3.17 | 3.17 |
| 728.81 | 7.01 | 7.01 |
| 446.57 | 3.99 | 3.99 |
| 702.79 | 7.42 | 7.42 |
| 678.25 | 6.21 | 6.21 |
| 740.28 | 7.09 | 7.09 |
| 684.80 | 7.28 | 7.28 |
| 563.68 | 3.03 | 3.03 |
| 544.69 | 3.35 | 3.35 |
| 641.02 | 5.80 | 5.80 |
| 600.65 | 4.81 | 4.81 |
| 446.52 | 4.52 | 4.52 |
| 468.55 | 4.04 | 4.04 |
| 714.83 | 7.29 | 7.29 |
| 720.76 | 7.03 | 7.03 |
| 719.87 | 6.74 | 6.74 |
| 602.68 | 4.99 | 4.99 |
| 723.83 | 6.57 | 6.57 |
| 434.58 | 4.64 | 4.64 |
| 414.51 | 3.46 | 3.46 |
| 511.69 | 3.52 | 3.52 |
| 741.18 | 7.38 | 7.38 |
| 706.73 | 6.72 | 6.72 |
| 741.18 | 7.38 | 7.38 |
| 592.67 | 3.14 | 3.14 |
| 713.80 | 7.31 | 7.31 |
| 537.66 | 4.26 | 4.26 |
| 477.56 | 3.93 | 3.93 |
| 428.53 | 2.58 | 2.58 |
| 418.49 | 1.81 | 1.81 |
| 402.47 | 3.59 | 3.59 |
| 494.61 | 3.93 | 3.93 |
| 751.35 | 7.25 | 7.25 |
| 605.76 | 4.53 | 4.53 |
| 562.73 | 3.99 | 3.99 |
| 672.29 | 6.07 | 6.07 |
| 683.81 | 6.81 | 6.81 |
| 683.81 | 6.81 | 6.81 |
| 483.59 | 4.68 | 4.68 |
| 463.48 | 3.83 | 3.83 |
| 669.79 | 6.89 | 6.89 |
| 685.79 | 6.67 | 6.67 |
| 635.85 | 5.53 | 5.53 |
| 735.90 | 4.75 | 4.75 |
| 622.85 | 6.64 | 6.64 |
| 705.84 | 6.43 | 6.43 |
| 679.78 | 6.19 | 6.19 |
| 343.43 | 2.90 | 2.90 |
| 583.73 | 2.88 | 2.88 |
| 430.55 | 4.32 | 4.32 |
| 550.68 | 3.99 | 3.99 |
| 423.47 | 2.98 | 2.98 |
| 594.66 | 3.50 | 3.50 |
| 645.80 | 5.57 | 5.57 |
| 684.80 | 7.28 | 7.28 |
| 556.61 | 3.34 | 3.34 |
| 735.90 | 4.75 | 4.75 |
| 549.69 | 3.39 | 3.39 |
| 719.90 | 5.05 | 5.05 |
| 741.18 | 7.38 | 7.38 |
| 740.32 | 5.40 | 5.40 |
| 756.77 | 5.91 | 5.91 |
| 698.78 | 6.92 | 6.92 |
| 562.73 | 3.99 | 3.99 |
| 714.83 | 7.29 | 7.29 |
| 465.60 | 4.54 | 4.54 |
| 723.83 | 6.57 | 6.57 |
| 698.78 | 6.92 | 6.92 |
| 566.72 | 3.31 | 3.31 |
| 705.84 | 6.43 | 6.43 |
| 753.69 | 8.58 | 8.58 |
| 618.68 | 5.12 | 5.12 |
| 706.73 | 6.72 | 6.72 |
| 483.57 | 4.07 | 4.07 |
| 722.33 | 5.26 | 5.26 |
| 705.84 | 6.43 | 6.43 |
| 734.89 | 6.74 | 6.74 |
| 429.52 | 4.34 | 4.34 |
| 683.81 | 6.81 | 6.81 |
| 734.84 | 6.47 | 6.47 |
| 684.80 | 7.28 | 7.28 |
| 724.72 | 6.86 | 6.86 |
| 692.32 | 5.98 | 5.98 |
| 735.87 | 6.44 | 6.44 |
| 549.69 | 3.39 | 3.39 |
| 717.91 | 4.61 | 4.61 |
| 423.60 | 4.86 | 4.86 |
| 380.53 | 4.51 | 4.51 |
| 472.49 | 3.18 | 3.18 |
| 649.73 | 4.80 | 4.80 |
| 764.86 | 6.47 | 6.47 |
| 420.55 | 4.62 | 4.62 |
| 698.78 | 6.92 | 6.92 |
| 702.79 | 7.42 | 7.42 |
| 513.61 | 4.69 | 4.69 |
| 705.84 | 6.43 | 6.43 |
| 637.70 | 4.93 | 4.93 |
| 443.45 | 4.25 | 4.25 |
| 690.63 | 7.20 | 7.20 |
| 674.84 | 6.43 | 6.43 |
| 450.56 | 1.95 | 1.95 |
| 449.60 | 4.58 | 4.58 |
| 702.79 | 7.42 | 7.42 |
| 723.83 | 6.57 | 6.57 |
| 723.83 | 6.57 | 6.57 |
| 731.79 | 7.45 | 7.45 |
| 707.94 | 4.97 | 4.97 |
| 661.88 | 5.93 | 5.93 |
| 683.81 | 6.81 | 6.81 |
| 412.49 | 3.02 | 3.02 |
| 555.72 | 4.98 | 4.98 |
| 689.74 | 6.91 | 6.91 |
| 740.28 | 7.09 | 7.09 |
| 683.81 | 6.81 | 6.81 |
| 566.72 | 3.31 | 3.31 |
| 566.72 | 3.31 | 3.31 |
| 669.79 | 6.89 | 6.89 |
| 501.63 | 4.70 | 4.70 |
| 473.60 | 4.10 | 4.10 |
| 550.68 | 2.79 | 2.79 |
| 719.87 | 6.74 | 6.74 |
| 573.74 | 5.29 | 5.29 |
| 623.67 | 5.00 | 5.00 |
| 743.82 | 7.32 | 7.32 |
| 451.49 | 5.65 | 5.65 |
| 769.28 | 7.12 | 7.12 |
| 753.69 | 8.58 | 8.58 |
| 705.84 | 6.43 | 6.43 |
| 736.35 | 5.57 | 5.57 |
| 753.69 | 8.58 | 8.58 |
| 537.66 | 4.26 | 4.26 |
| 549.69 | 3.39 | 3.39 |
| 460.55 | 4.34 | 4.34 |
| 622.69 | 6.39 | 6.39 |
| 577.14 | 3.51 | 3.51 |
| 689.74 | 6.91 | 6.91 |
| 490.67 | 4.58 | 4.58 |
| 669.79 | 6.89 | 6.89 |
| 466.65 | 3.59 | 3.59 |
| 728.81 | 7.01 | 7.01 |
| 592.67 | 3.14 | 3.14 |
| 583.73 | 2.88 | 2.88 |
| 643.89 | 5.80 | 5.80 |
| 724.72 | 6.86 | 6.86 |
| 419.57 | 4.57 | 4.57 |
| 703.68 | 7.70 | 7.70 |
| 581.59 | 5.32 | 5.32 |
| 736.35 | 5.57 | 5.57 |
| 719.90 | 5.05 | 5.05 |
| 319.41 | 2.42 | 2.42 |
| 740.28 | 7.09 | 7.09 |
| 487.51 | 3.57 | 3.57 |
| 593.72 | 4.66 | 4.66 |
| 417.48 | 4.47 | 4.47 |
| 753.84 | 6.07 | 6.07 |
| 698.78 | 6.92 | 6.92 |
| 583.73 | 2.88 | 2.88 |
| 386.45 | 2.68 | 2.68 |
| 752.35 | 5.27 | 5.27 |
| 669.79 | 6.89 | 6.89 |
| 724.84 | 6.04 | 6.04 |
| 722.33 | 5.26 | 5.26 |
| 433.60 | 3.17 | 3.17 |
| 719.87 | 6.74 | 6.74 |
| 720.76 | 7.03 | 7.03 |
| 714.83 | 7.29 | 7.29 |
| 711.87 | 6.50 | 6.50 |
| 678.34 | 6.45 | 6.45 |
| 643.73 | 5.54 | 5.54 |
| 662.73 | 5.13 | 5.13 |
| 806.43 | 6.90 | 6.90 |
| 740.28 | 7.09 | 7.09 |
| 734.84 | 6.47 | 6.47 |
| 735.87 | 6.44 | 6.44 |
| 684.80 | 7.28 | 7.28 |
| 700.30 | 5.64 | 5.64 |
| 674.84 | 5.84 | 5.84 |
| 695.66 | 6.68 | 6.68 |
| 371.53 | 3.11 | 3.11 |
| 798.85 | 8.03 | 8.03 |
| 719.85 | 7.12 | 7.12 |
| 689.74 | 6.91 | 6.91 |
| 599.65 | 5.03 | 5.03 |
| 419.57 | 4.57 | 4.57 |
| 605.76 | 4.53 | 4.53 |
| 620.73 | 4.43 | 4.43 |
| 719.87 | 6.74 | 6.74 |
| 698.78 | 6.92 | 6.92 |
| 751.35 | 7.25 | 7.25 |
| 723.83 | 6.57 | 6.57 |
| 581.59 | 5.32 | 5.32 |
| 571.72 | 3.97 | 3.97 |
| 523.51 | 3.50 | 3.50 |
| 336.41 | 3.17 | 3.17 |
| 684.80 | 7.28 | 7.28 |
| 451.49 | 5.65 | 5.65 |
| 467.61 | 4.25 | 4.25 |
| 651.19 | 5.68 | 5.68 |
| 684.80 | 7.28 | 7.28 |
| 580.73 | 4.72 | 4.72 |
| 728.81 | 7.01 | 7.01 |
| 740.32 | 5.40 | 5.40 |
| 657.83 | 5.44 | 5.44 |
| 539.70 | 3.29 | 3.29 |
| 698.78 | 6.92 | 6.92 |
| 769.28 | 7.12 | 7.12 |
| 740.28 | 7.09 | 7.09 |
| 753.84 | 6.07 | 6.07 |
| 684.80 | 7.28 | 7.28 |
| 781.79 | 8.33 | 8.33 |
| 428.53 | 3.85 | 3.85 |
| 618.68 | 5.12 | 5.12 |
| 499.68 | 3.38 | 3.38 |
| 463.58 | 2.25 | 2.25 |
| 769.28 | 7.12 | 7.12 |
| 387.48 | 2.94 | 2.94 |
| 466.65 | 3.59 | 3.59 |
| 566.72 | 3.31 | 3.31 |
| 696.89 | 7.42 | 7.42 |
| 495.62 | 4.55 | 4.55 |
| 562.73 | 3.99 | 3.99 |
| 684.80 | 7.28 | 7.28 |
| 583.73 | 2.88 | 2.88 |
| 714.83 | 7.29 | 7.29 |
| 485.63 | 5.13 | 5.13 |
| 716.30 | 5.80 | 5.80 |
| 728.81 | 7.01 | 7.01 |
| 643.73 | 5.54 | 5.54 |
| 482.65 | 3.32 | 3.32 |
| 731.79 | 7.45 | 7.45 |
| 735.87 | 6.44 | 6.44 |
| 549.69 | 3.39 | 3.39 |
| 562.73 | 3.99 | 3.99 |
| 490.67 | 4.58 | 4.58 |
| 692.32 | 5.98 | 5.98 |
| 654.82 | 6.30 | 6.30 |
| 698.78 | 6.92 | 6.92 |
| 655.83 | 5.55 | 5.55 |
| 400.48 | 3.07 | 3.07 |
| 643.73 | 5.54 | 5.54 |
| 685.79 | 6.67 | 6.67 |
| 504.58 | 2.73 | 2.73 |
| 711.87 | 6.50 | 6.50 |
| 645.76 | 7.02 | 7.02 |
| 480.61 | 4.11 | 4.11 |
| 690.85 | 7.09 | 7.09 |
| 728.81 | 7.01 | 7.01 |
| 740.87 | 6.53 | 6.53 |
| 719.90 | 5.05 | 5.05 |
| 690.63 | 7.20 | 7.20 |
| 491.62 | 5.02 | 5.02 |
| 416.50 | 3.98 | 3.98 |
| 719.28 | 6.24 | 6.24 |
| 449.60 | 4.58 | 4.58 |
| 490.60 | 4.10 | 4.10 |
| 438.59 | 4.49 | 4.49 |
| 364.49 | 3.60 | 3.60 |
| 752.83 | 6.60 | 6.60 |
| 623.84 | 5.46 | 5.46 |
| 456.51 | 4.17 | 4.17 |
| 753.84 | 6.07 | 6.07 |
| 417.48 | 4.25 | 4.25 |
| 731.79 | 7.45 | 7.45 |
| 413.50 | 4.97 | 4.97 |
| 328.44 | 2.05 | 2.05 |
| 593.69 | 6.35 | 6.35 |
| 564.68 | 3.70 | 3.70 |
| 707.33 | 5.91 | 5.91 |
| 393.51 | 4.27 | 4.27 |
| 605.68 | 5.61 | 5.61 |
| 571.10 | 4.33 | 4.33 |
| 736.91 | 4.22 | 4.22 |
| 590.76 | 3.33 | 3.33 |
| 678.25 | 6.21 | 6.21 |
| 741.33 | 4.86 | 4.86 |
| 734.84 | 6.47 | 6.47 |
| 669.79 | 6.89 | 6.89 |
| 705.84 | 6.43 | 6.43 |
| 516.68 | 4.12 | 4.12 |
| 593.72 | 4.66 | 4.66 |
| 639.60 | 4.68 | 4.68 |
| 482.58 | 4.06 | 4.06 |
| 690.85 | 7.09 | 7.09 |
| 736.35 | 5.57 | 5.57 |
| 412.49 | 2.35 | 2.35 |
| 719.85 | 7.12 | 7.12 |
| 736.35 | 5.57 | 5.57 |
| 410.52 | 4.53 | 4.53 |
| 573.74 | 3.87 | 3.87 |
| 719.85 | 7.12 | 7.12 |
| 713.80 | 7.31 | 7.31 |
| 723.83 | 6.57 | 6.57 |
| 566.58 | 5.81 | 5.81 |
| 484.66 | 3.74 | 3.74 |
| 619.12 | 4.66 | 4.66 |
| 722.33 | 5.26 | 5.26 |
| 702.82 | 5.73 | 5.73 |
| 740.28 | 7.09 | 7.09 |
| 442.56 | 4.32 | 4.32 |
| 593.72 | 4.66 | 4.66 |
| 494.61 | 3.93 | 3.93 |
| 740.87 | 6.53 | 6.53 |
| 735.87 | 6.44 | 6.44 |
| 637.70 | 4.93 | 4.93 |
| 538.62 | 3.55 | 3.55 |
| 712.76 | 6.78 | 6.78 |
| 736.35 | 5.57 | 5.57 |
| 714.83 | 7.29 | 7.29 |
| 620.60 | 5.08 | 5.08 |
| 645.80 | 5.57 | 5.57 |
| 581.59 | 5.32 | 5.32 |
| 594.66 | 3.50 | 3.50 |
| 735.87 | 6.44 | 6.44 |
| 511.69 | 3.52 | 3.52 |
| 719.87 | 6.74 | 6.74 |
| 620.60 | 5.08 | 5.08 |
| 642.68 | 5.36 | 5.36 |
| 619.71 | 4.79 | 4.79 |
| 513.61 | 4.69 | 4.69 |
| 752.83 | 6.60 | 6.60 |
| 466.65 | 3.62 | 3.62 |
| 716.30 | 5.80 | 5.80 |
| 562.73 | 3.99 | 3.99 |
| 483.59 | 3.61 | 3.61 |
| 705.84 | 6.43 | 6.43 |
| 522.62 | 3.43 | 3.43 |
| 452.55 | 4.34 | 4.34 |
| 428.53 | 3.85 | 3.85 |
| 569.58 | 5.09 | 5.09 |
| 571.10 | 4.33 | 4.33 |
| 701.91 | 4.91 | 4.91 |
| 719.87 | 6.74 | 6.74 |
| 683.81 | 6.81 | 6.81 |
| 436.49 | 4.67 | 4.67 |
| 734.89 | 6.74 | 6.74 |
| 723.83 | 6.57 | 6.57 |
| 769.28 | 7.12 | 7.12 |
| 494.61 | 3.93 | 3.93 |
| 698.78 | 6.92 | 6.92 |
| 429.55 | 3.66 | 3.66 |
| 622.85 | 6.64 | 6.64 |
| 715.72 | 7.57 | 7.57 |
| 593.72 | 4.66 | 4.66 |
| 423.47 | 2.98 | 2.98 |
| 690.85 | 7.09 | 7.09 |
| 723.83 | 6.57 | 6.57 |
| 662.73 | 5.13 | 5.13 |
| 683.81 | 6.81 | 6.81 |
| 605.76 | 4.53 | 4.53 |
| 432.50 | 2.52 | 2.52 |
| 554.64 | 3.82 | 3.82 |
| 703.68 | 7.70 | 7.70 |
| 728.81 | 7.01 | 7.01 |
| 513.61 | 4.69 | 4.69 |
| 735.90 | 4.75 | 4.75 |
| 468.62 | 2.34 | 2.34 |
| 348.45 | 3.04 | 3.04 |
| 552.62 | 3.60 | 3.60 |
| 556.87 | 4.49 | 4.49 |
| 740.32 | 5.40 | 5.40 |
| 719.87 | 6.74 | 6.74 |
| 343.43 | 2.90 | 2.90 |
| 751.35 | 7.25 | 7.25 |
| 549.69 | 3.39 | 3.39 |
| 741.18 | 7.38 | 7.38 |
| 719.28 | 6.24 | 6.24 |
| 670.68 | 7.17 | 7.17 |
| 569.70 | 5.64 | 5.64 |
| 670.68 | 7.17 | 7.17 |
| 719.87 | 6.74 | 6.74 |
| 561.03 | 3.98 | 3.98 |
| 740.28 | 7.09 | 7.09 |
| 719.87 | 6.74 | 6.74 |
| 684.71 | 7.10 | 7.10 |
| 756.77 | 5.91 | 5.91 |
| 684.80 | 7.28 | 7.28 |
| 495.62 | 4.55 | 4.55 |
| 437.47 | 5.34 | 5.34 |
| 578.75 | 3.74 | 3.74 |
| 728.35 | 5.32 | 5.32 |
| 781.79 | 8.33 | 8.33 |
| 753.69 | 8.58 | 8.58 |
| 702.79 | 7.42 | 7.42 |
| 399.45 | 3.25 | 3.25 |
| 752.35 | 5.27 | 5.27 |
| 731.93 | 4.92 | 4.92 |
| 740.28 | 7.09 | 7.09 |
| 753.69 | 8.58 | 8.58 |
| 728.81 | 7.01 | 7.01 |
| 716.90 | 6.60 | 6.60 |
| 612.51 | 5.34 | 5.34 |
| 728.35 | 5.32 | 5.32 |
| 685.69 | 7.56 | 7.56 |
| 606.72 | 4.94 | 4.94 |
| 753.69 | 8.58 | 8.58 |
| 394.49 | 3.58 | 3.58 |
| 669.79 | 6.89 | 6.89 |
| 683.81 | 6.81 | 6.81 |
| 678.73 | 4.83 | 4.83 |
| 740.32 | 5.40 | 5.40 |
| 472.49 | 3.18 | 3.18 |
| 685.79 | 6.67 | 6.67 |
| 364.49 | 3.60 | 3.60 |
| 730.93 | 6.91 | 6.91 |
| 683.81 | 6.81 | 6.81 |
| 420.55 | 4.25 | 4.25 |
| 417.48 | 4.25 | 4.25 |
| 649.73 | 4.80 | 4.80 |
| 740.32 | 5.40 | 5.40 |
| 740.32 | 5.40 | 5.40 |
| 654.15 | 5.44 | 5.44 |
| 723.83 | 6.57 | 6.57 |
| 465.60 | 4.54 | 4.54 |
| 451.53 | 2.01 | 2.01 |
| 619.69 | 5.54 | 5.54 |
| 358.46 | 4.43 | 4.43 |
| 684.71 | 7.10 | 7.10 |
| 461.61 | 4.72 | 4.72 |
| 473.59 | 5.26 | 5.26 |