Basic Information
ID: ALA3215269
Type: Functional
Description: PubChem BioAssay. SAR Analysis for the identification of inhibitors of the two-pore domain potassium channel TASK1 (KCNK3). (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3215269
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.55 | 5.43 | 5.43 |
| 360.41 | 4.51 | 4.51 |
| 364.83 | 5.15 | 5.15 |
| 330.39 | 4.50 | 4.50 |
| 360.41 | 4.51 | 4.51 |
| 334.35 | 4.33 | 4.33 |
| 317.35 | 3.59 | 3.59 |
| 342.83 | 4.72 | 4.72 |
| 352.43 | 4.47 | 4.47 |
| 306.32 | 3.78 | 3.78 |
| 468.60 | 4.93 | 4.93 |
| 344.41 | 4.81 | 4.81 |
| 386.50 | 5.80 | 5.80 |
| 336.42 | 4.56 | 4.56 |
| 324.38 | 3.69 | 3.69 |
| 376.41 | 4.21 | 4.21 |
| 317.35 | 3.59 | 3.59 |
| 428.41 | 5.61 | 5.61 |
| 348.38 | 4.64 | 4.64 |
| 458.44 | 5.88 | 5.88 |
| 390.44 | 4.60 | 4.60 |
| 414.38 | 5.40 | 5.40 |
| 352.43 | 4.01 | 4.01 |
| 352.43 | 4.47 | 4.47 |
| 320.35 | 4.09 | 4.09 |
| 322.39 | 4.25 | 4.25 |
| 350.81 | 4.84 | 4.84 |
| 336.44 | 4.77 | 4.77 |
| 378.40 | 4.65 | 4.65 |
| 378.40 | 4.65 | 4.65 |
| 374.44 | 4.90 | 4.90 |
| 390.44 | 4.60 | 4.60 |
| 428.41 | 5.61 | 5.61 |
| 398.38 | 5.52 | 5.52 |
| 378.40 | 4.65 | 4.65 |
| 346.39 | 4.20 | 4.20 |
| 322.39 | 4.25 | 4.25 |
| 334.35 | 4.33 | 4.33 |
| 366.46 | 4.86 | 4.86 |
| 322.41 | 4.46 | 4.46 |
| 390.44 | 4.52 | 4.52 |
| 372.47 | 5.62 | 5.62 |
| 361.40 | 3.90 | 3.90 |
| 330.39 | 4.50 | 4.50 |
| 359.43 | 4.26 | 4.26 |
| 366.44 | 4.05 | 4.05 |
| 354.41 | 3.46 | 3.46 |
| 394.86 | 5.24 | 5.24 |
| 340.42 | 4.32 | 4.32 |
| 350.81 | 4.84 | 4.84 |
| 390.44 | 4.60 | 4.60 |
| 352.43 | 4.47 | 4.47 |
| 352.43 | 4.47 | 4.47 |
| 390.44 | 4.60 | 4.60 |
| 344.41 | 4.81 | 4.81 |
| 428.41 | 5.61 | 5.61 |
| 442.44 | 6.21 | 6.21 |
| 346.39 | 4.20 | 4.20 |
| 360.41 | 4.59 | 4.59 |
| 384.36 | 5.21 | 5.21 |
| 330.39 | 4.50 | 4.50 |
| 330.39 | 4.50 | 4.50 |
| 352.43 | 4.47 | 4.47 |
| 352.43 | 4.47 | 4.47 |
| 402.49 | 5.53 | 5.53 |
| 364.83 | 5.15 | 5.15 |
| 316.36 | 4.19 | 4.19 |
| 364.83 | 5.15 | 5.15 |
| 414.38 | 5.22 | 5.22 |
| 384.36 | 5.21 | 5.21 |
| 394.86 | 5.24 | 5.24 |
| 366.46 | 4.86 | 4.86 |
| 374.44 | 4.90 | 4.90 |
| 396.45 | 5.35 | 5.35 |
| 394.86 | 5.24 | 5.24 |
| 388.47 | 5.32 | 5.32 |
| 360.41 | 4.51 | 4.51 |
| 331.38 | 3.89 | 3.89 |
| 374.44 | 4.90 | 4.90 |
| 306.32 | 3.78 | 3.78 |
| 444.41 | 5.49 | 5.49 |
| 338.41 | 4.08 | 4.08 |
| 428.41 | 5.61 | 5.61 |
| 317.35 | 3.59 | 3.59 |
| 380.49 | 5.25 | 5.25 |
| 376.41 | 4.21 | 4.21 |
| 406.46 | 5.46 | 5.46 |
| 346.39 | 4.20 | 4.20 |
| 346.39 | 4.20 | 4.20 |
| 373.46 | 4.57 | 4.57 |
| 360.41 | 4.51 | 4.51 |
| 430.38 | 5.10 | 5.10 |
| 354.41 | 3.31 | 3.31 |
| 374.44 | 4.90 | 4.90 |