Basic Information
ID: ALA3223538
Type: Binding
Description: Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of p21 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis
Organism: Homo sapiens
Cell type: A2780
Activity Charts
Bioactivity
Activity Types for Assay ALA3223538
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.98 | 5.38 | 5.38 |
| 560.08 | 7.30 | 7.30 |
| 410.52 | 2.82 | 2.82 |