Assay Report Card

Basic Information

ID: ALA3223543

Type: Binding

Description: Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of MDM2 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis

Organism: Homo sapiens

Cell type: A2780

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
483.985.385.38
560.087.307.30
410.522.822.82