Basic Information
ID: ALA3223546
Type: Binding
Description: Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of MDM2 protein expression at 5 uM after 4 hrs by western blot analysis
Organism: Homo sapiens
Cell type: SJSA-1
Activity Charts
Bioactivity
Activity Types for Assay ALA3223546
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.98 | 5.38 | 5.38 |
| 560.08 | 7.30 | 7.30 |
| 410.52 | 2.82 | 2.82 |