Basic Information
ID: ALA3224414
Type: Binding
Description: Competitive reversible inhibition of Mycobacterium tuberculosis type 2 dehydroquinase expressed in Escherichia coli BL21 (DE3) cells assessed as enone-carboxylate chromophore of 3-dehydroshikimate formation using 3-dehydroquinate as substrate preincubated with enzyme for 3 mins prior to substrate addition by UV spectrophotometric assay
Organism: Mycobacterium tuberculosis
Cell type: BL21-DE3
Activity Charts
Bioactivity
Activity Types for Assay ALA3224414
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.30 | -0.41 | -0.41 |
| 335.29 | -0.27 | -0.27 |
| 362.30 | -0.50 | -0.50 |
| 361.31 | -0.71 | -0.71 |
| 333.30 | -0.70 | -0.70 |
| 318.29 | -1.01 | -1.01 |
| 321.29 | -0.76 | -0.76 |
| 337.36 | -0.29 | -0.29 |