Basic Information
ID: ALA3225245
Type: Functional
Description: Antiplasmodial activity against liver stage of Plasmodium berghei sporozoites expressing firefly luciferase infected in human Huh7 cells assessed as inhibition of parasite development treated 1 hr prior to infection followed by compound replenisment at 24 hrs post-infection measured 48 hrs after infection by bioluminescence analysis
Organism: Plasmodium berghei
Tissue: Liver
Cell type: Huh-7
Activity Charts
Bioactivity
Activity Types for Assay ALA3225245
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 259.35 | 2.78 | 2.78 |
| 419.53 | 4.66 | 4.66 |
| 389.50 | 4.65 | 4.65 |
| 403.53 | 4.96 | 4.96 |
| 431.58 | 5.78 | 5.78 |
| 407.49 | 4.79 | 4.79 |
| 407.49 | 4.79 | 4.79 |
| 423.94 | 5.31 | 5.31 |
| 468.40 | 5.42 | 5.42 |
| 434.50 | 4.56 | 4.56 |
| 434.50 | 4.56 | 4.56 |
| 434.50 | 4.56 | 4.56 |