Basic Information
ID: ALA3225553
Type: Functional
Description: Antagonist activity at human recombinant histamine H3 receptor expressed in Sf9 cells coexpressing Galphai2,Gbeta1gamma2 and RGS4 assessed as inhibition of histamine-induced [gamma33P]GTP hydrolysis preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3225553
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.45 | 2.80 | 2.80 |
| 375.48 | 2.93 | 2.93 |
| 313.41 | 1.97 | 1.97 |
| 319.43 | 2.03 | 2.03 |
| 375.48 | 3.00 | 3.00 |
| 382.49 | 2.45 | 2.45 |
| 313.41 | 1.97 | 1.97 |
| 375.48 | 3.00 | 3.00 |
| 314.39 | 1.36 | 1.36 |
| 376.46 | 2.39 | 2.39 |
| 323.44 | 3.24 | 3.24 |
| 385.51 | 4.27 | 4.27 |
| 324.43 | 2.64 | 2.64 |
| 386.50 | 3.67 | 3.67 |
| 324.43 | 2.64 | 2.64 |
| 386.50 | 3.67 | 3.67 |
| 324.43 | 2.64 | 2.64 |
| 386.50 | 3.67 | 3.67 |
| 370.50 | 2.90 | 2.90 |
| 376.53 | 2.96 | 2.96 |
| 432.57 | 3.93 | 3.93 |
| 439.59 | 3.38 | 3.38 |
| 313.41 | 1.90 | 1.90 |