Basic Information
ID: ALA3225555
Type: Functional
Description: Antagonist activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 assessed as inhibition of histamine-induced [gamma33P]GTP hydrolysis preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3225555
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.49 | 1.67 | 1.67 |
| 375.48 | 2.93 | 2.93 |
| 313.41 | 1.97 | 1.97 |
| 375.48 | 3.00 | 3.00 |
| 313.41 | 1.97 | 1.97 |
| 375.48 | 3.00 | 3.00 |
| 314.39 | 1.36 | 1.36 |
| 376.46 | 2.39 | 2.39 |
| 234.31 | 0.69 | 0.69 |
| 356.50 | 2.85 | 2.85 |
| 220.28 | 0.30 | 0.30 |
| 342.47 | 2.46 | 2.46 |
| 234.31 | 0.69 | 0.69 |
| 356.50 | 2.85 | 2.85 |
| 343.46 | 1.94 | 1.94 |
| 356.46 | 1.28 | 1.28 |
| 248.33 | 1.01 | 1.01 |
| 370.53 | 3.17 | 3.17 |
| 358.48 | 1.52 | 1.52 |
| 354.48 | 2.69 | 2.69 |
| 246.32 | 0.92 | 0.92 |
| 368.51 | 3.08 | 3.08 |
| 356.46 | 1.28 | 1.28 |
| 248.29 | -0.49 | -0.49 |
| 323.44 | 3.24 | 3.24 |
| 385.51 | 4.27 | 4.27 |
| 324.43 | 2.64 | 2.64 |
| 386.50 | 3.67 | 3.67 |
| 324.43 | 2.64 | 2.64 |
| 386.50 | 3.67 | 3.67 |
| 324.43 | 2.64 | 2.64 |
| 386.50 | 3.67 | 3.67 |
| 370.50 | 2.90 | 2.90 |
| 432.57 | 3.93 | 3.93 |
| 313.41 | 1.90 | 1.90 |