Basic Information
ID: ALA3226385
Type: Binding
Description: Inhibition of N-terminal GST-tagged ROCK1 (1 to 535) (unknown origin) using KKRPQRRSNVF as substrate after 1 hr by Z-Lyte-based FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3226385
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.38 | 2.98 | 2.98 |
| 310.38 | 3.53 | 3.53 |
| 340.41 | 3.54 | 3.54 |
| 340.41 | 3.54 | 3.54 |
| 325.40 | 3.11 | 3.11 |
| 349.42 | 4.01 | 4.01 |
| 326.38 | 3.23 | 3.23 |
| 326.38 | 3.23 | 3.23 |
| 326.38 | 3.23 | 3.23 |
| 368.42 | 3.02 | 3.02 |
| 403.49 | 2.90 | 2.90 |
| 367.43 | 3.49 | 3.49 |
| 384.46 | 3.55 | 3.55 |
| 354.44 | 3.93 | 3.93 |
| 368.46 | 4.32 | 4.32 |
| 368.46 | 4.31 | 4.31 |
| 328.37 | 3.67 | 3.67 |
| 328.37 | 3.67 | 3.67 |
| 328.37 | 3.67 | 3.67 |
| 344.83 | 4.18 | 4.18 |
| 344.83 | 4.18 | 4.18 |
| 344.83 | 4.18 | 4.18 |
| 324.41 | 3.84 | 3.84 |
| 324.41 | 3.84 | 3.84 |
| 324.41 | 3.84 | 3.84 |
| 324.41 | 3.87 | 3.87 |
| 354.44 | 3.56 | 3.56 |
| 354.44 | 3.88 | 3.88 |
| 324.41 | 4.09 | 4.09 |
| 340.41 | 3.06 | 3.06 |
| 338.44 | 4.48 | 4.48 |
| 353.41 | 2.55 | 2.55 |
| 354.44 | 3.71 | 3.71 |
| 354.44 | 4.10 | 4.10 |
| 342.40 | 4.23 | 4.23 |
| 358.85 | 4.74 | 4.74 |
| 324.41 | 4.09 | 4.09 |
| 340.41 | 3.06 | 3.06 |
| 338.44 | 4.48 | 4.48 |
| 353.41 | 2.55 | 2.55 |
| 354.44 | 3.71 | 3.71 |
| 354.44 | 4.10 | 4.10 |
| 342.40 | 4.23 | 4.23 |
| 358.85 | 4.74 | 4.74 |
| 338.44 | 4.43 | 4.43 |
| 338.44 | 4.43 | 4.43 |
| 340.41 | 3.06 | 3.06 |
| 342.40 | 4.23 | 4.23 |
| 324.41 | 3.57 | 3.57 |