Basic Information
ID: ALA3226465
Type: Binding
Description: Positive allosteric modulation of AMPA receptor in embryonic rat brain cells assessed as concentration required for 2-fold increase in AMPA-induced membrane depolarization after 3 mins by fluorescence assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: brain
Target: Glutamate receptor ionotropic, AMPA(ALA2093871)
Document: ALA3217522
Positive allosteric modulation of AMPA receptor in embryonic rat brain cells assessed as concentration required for 2-fold increase in AMPA-induced membrane depolarization after 3 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3226465
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 318.35 | 1.59 | 1.59 |
| 332.38 | 1.90 | 1.90 |
| 346.41 | 2.29 | 2.29 |
| 332.38 | 1.90 | 1.90 |
| 346.41 | 2.29 | 2.29 |
| 346.41 | 2.29 | 2.29 |
| 346.41 | 2.15 | 2.15 |
| 360.44 | 2.54 | 2.54 |
| 374.46 | 2.93 | 2.93 |
| 374.46 | 2.93 | 2.93 |
| 334.35 | 1.58 | 1.58 |
| 348.38 | 1.60 | 1.60 |
| 362.41 | 1.99 | 1.99 |
| 362.41 | 1.99 | 1.99 |
| 362.41 | 1.99 | 1.99 |
| 362.41 | 1.99 | 1.99 |
| 376.43 | 2.38 | 2.38 |
| 424.48 | 3.17 | 3.17 |
| 438.51 | 3.56 | 3.56 |
| 438.51 | 3.56 | 3.56 |
| 346.41 | 2.12 | 2.12 |
| 360.44 | 2.16 | 2.16 |
| 317.37 | 1.62 | 1.62 |
| 331.40 | 1.65 | 1.65 |
| 345.42 | 2.04 | 2.04 |
| 331.40 | 2.01 | 2.01 |