Basic Information
ID: ALA3226858
Type: ADME
Description: Drug metabolism in human U937 cell lysate assessed as human CE1-mediated N-[2-(4-{6-Amino-5-[(2,4-difluorophenyl)carbonyl]-2-oxopyridin-1(2H)-yl}-3,5 difluorophenyl)ethyl]-L-leucine formation at 2.5 uM after 10 to 80 mins by LC/MS/MS analysis
Organism: Homo sapiens
Cell type: U-937
Subcellular Fraction: Lysate
Activity Charts
Bioactivity
Activity Types for Assay ALA3226858
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 587.61 | 5.24 | 5.24 |