Basic Information
ID: ALA3226864
Type: ADME
Description: Drug metabolism in human U937 cell lysate assessed as human CE1-mediated 5-(4-{6-Amino-5-[(2,4-difluorophenyl)carbonyl]-2-oxopyridiny1(2H)-yl}-3,5-difluorophenoxy)-L-norvaline formation at 2.5 uM after 10 to 80 mins by LC/MS/MS analysis
Organism: Homo sapiens
Cell type: U-937
Subcellular Fraction: Lysate
Activity Charts
Bioactivity
Activity Types for Assay ALA3226864
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 561.53 | 4.18 | 4.18 |