Assay Report Card

Basic Information

ID: ALA3226867

Type: ADME

Description: Drug metabolism in intact human U937 cells assessed as human CE1-mediated N-[2-(4-{6-Amino-5-[(2,4-difluorophenyl)carbonyl]-2-oxopyridin-1(2H)-yl}-3,5 difluorophenyl)ethyl]-L-leucine formation per million cells at 2.5 uM after 6 hrs by LC/MS/MS analysis

Organism: Homo sapiens

Cell type: U-937

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
587.615.245.24