Basic Information
ID: ALA3227401
Type: Functional
Description: Agonist activity at TSHR (unknown origin) transiently transfected HEK-EM293 cells assessed as cAMP level after 1 hr by ELISA relative to N-(4-(5-(3-Benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyloxy)phenyl)acetamide
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-EM293
Target: Thyroid stimulating hormone receptor(ALA1963)
Document: ALA3217527
Agonist activity at TSHR (unknown origin) transiently transfected HEK-EM293 cells assessed as cAMP level after 1 hr by ELISA relative to N-(4-(5-(3-Benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyloxy)phenyl)acetamide: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3227401
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.57 | 5.60 | 5.60 |
| 507.59 | 6.00 | 6.00 |
| 497.55 | 5.59 | 5.59 |
| 505.57 | 5.66 | 5.66 |
| 495.54 | 5.25 | 5.25 |
| 461.52 | 3.79 | 3.79 |
| 537.62 | 6.01 | 6.01 |
| 480.56 | 6.05 | 6.05 |
| 508.58 | 5.39 | 5.39 |
| 521.62 | 6.04 | 6.04 |
| 493.56 | 6.00 | 6.00 |
| 502.62 | 4.75 | 4.75 |
| 523.59 | 5.70 | 5.70 |
| 507.59 | 6.00 | 6.00 |
| 525.58 | 6.14 | 6.14 |
| 417.47 | 4.09 | 4.09 |
| 468.53 | 6.18 | 6.18 |
| 539.66 | 6.42 | 6.42 |
| 475.55 | 5.91 | 5.91 |
| 521.57 | 5.36 | 5.36 |
| 523.66 | 6.71 | 6.71 |
| 477.56 | 5.99 | 5.99 |
| 450.54 | 6.04 | 6.04 |