Basic Information
ID: ALA3227453
Type: Binding
Description: Antagonist activity at human TRPV4 expressed in CHOK1 cells assessed as inhibition of PF-04674114/GSK1016790A-induced changes in intracellular calcium level measured for 5 mins by FLIPR assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3227453
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.33 | 3.60 | 3.60 |
| 449.89 | 2.82 | 2.82 |
| 441.34 | 3.46 | 3.46 |
| 440.46 | 2.04 | 2.04 |
| 421.84 | 2.04 | 2.04 |
| 438.29 | 2.55 | 2.55 |
| 431.27 | 2.82 | 2.82 |
| 438.29 | 2.55 | 2.55 |